Malignant hyperthermia: an inherited disorder of skeletal muscle Ca+ regulation.
about
Gene dose influences cellular and calcium channel dysregulation in heterozygous and homozygous T4826I-RYR1 malignant hyperthermia-susceptible muscle.A peripheral governor regulates muscle contraction.Reduced threshold for luminal Ca2+ activation of RyR1 underlies a causal mechanism of porcine malignant hyperthermia.Ryanodine receptor type 1 (RyR1) possessing malignant hyperthermia mutation R615C exhibits heightened sensitivity to dysregulation by non-coplanar 2,2',3,5',6-pentachlorobiphenyl (PCB 95).Antibody probe study of Ca2+ channel regulation by interdomain interaction within the ryanodine receptor.Reduced threshold for store overload-induced Ca2+ release is a common defect of RyR1 mutations associated with malignant hyperthermia and central core disease.
P2860
Malignant hyperthermia: an inherited disorder of skeletal muscle Ca+ regulation.
description
2001 nî lūn-bûn
@nan
2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Malignant hyperthermia: an inherited disorder of skeletal muscle Ca+ regulation.
@ast
Malignant hyperthermia: an inherited disorder of skeletal muscle Ca+ regulation.
@en
Malignant hyperthermia: an inherited disorder of skeletal muscle Ca+ regulation.
@nl
type
label
Malignant hyperthermia: an inherited disorder of skeletal muscle Ca+ regulation.
@ast
Malignant hyperthermia: an inherited disorder of skeletal muscle Ca+ regulation.
@en
Malignant hyperthermia: an inherited disorder of skeletal muscle Ca+ regulation.
@nl
prefLabel
Malignant hyperthermia: an inherited disorder of skeletal muscle Ca+ regulation.
@ast
Malignant hyperthermia: an inherited disorder of skeletal muscle Ca+ regulation.
@en
Malignant hyperthermia: an inherited disorder of skeletal muscle Ca+ regulation.
@nl
P2093
P356
P1433
P1476
Malignant hyperthermia: an inherited disorder of skeletal muscle Ca+ regulation.
@en
P2093
P2888
P304
P356
10.1023/A:1013644107519
P577
2001-04-01T00:00:00Z
P6179
1029806557