Multivariate analyses of amyloid-beta oligomer populations indicate a connection between pore formation and cytotoxicity
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Activity and architecture of pyroglutamate-modified amyloid-β (AβpE3-42) poresDifferences between amyloid-β aggregation in solution and on the membrane: insights into elucidation of the mechanistic details of Alzheimer's disease.rAAV/ABAD-DP-6His attenuates oxidative stress-induced injury of PC12 cells.Mechanisms for the Insertion of Toxic, Fibril-like β-Amyloid Oligomers into the Membrane.Alzheimer's disease: which type of amyloid-preventing drug agents to employ?Amyloid β oligomers in Alzheimer's disease pathogenesis, treatment, and diagnosis.Cytotoxic helix-rich oligomer formation by melittin and pancreatic polypeptideAnalyzing and Modeling the Kinetics of Amyloid Beta Pores Associated with Alzheimer's Disease Pathology.Benzothiazole Amphiphiles Promote the Formation of Dendritic Spines in Primary Hippocampal Neurons.Amyloid β-protein oligomers and Alzheimer's disease.Misfolding of amyloidogenic proteins and their interactions with membranes.Amyloid pore-channel hypothesis: effect of ethanol on aggregation state using frog oocytes for an Alzheimer's disease study.Key Points Concerning Amyloid Infectivity and Prion-Like Neuronal InvasionSuppression of glypican-1 autodegradation by NO-deprivation correlates with nuclear accumulation of amyloid beta in normal fibroblasts.MD simulations and multivariate studies for modeling the antileishmanial activity of peptides.Modulation of the Aβ peptide aggregation pathway by KP1019 limits Aβ-associated neurotoxicity.Ion Channel Formation by Amyloid-β42 Oligomers but Not Amyloid-β40 in Cellular Membranes.Ultra rapid in vivo screening for anti-Alzheimer anti-amyloid drugs.β-Hairpin mimics containing a piperidine-pyrrolidine scaffold modulate the β-amyloid aggregation process preserving the monomer species.Design of metastable β-sheet oligomers from natively unstructured peptide.Single-cell screening of cytosolic [Ca(2+)] reveals cell-selective action by the Alzheimer's Aβ peptide ion channel.Unmodified and pyroglutamylated amyloid β peptides form hypertoxic hetero-oligomers of unique secondary structure.An improved capillary electrophoresis method for in vitro monitoring of the challenging early steps of Aβ1-42 peptide oligomerization: application to anti-Alzheimer's drug discovery.A hyperpolarization-activated ion current of amphibian oocytes.Modeling the neuron as a nanocommunication system to identify spatiotemporal molecular events in neurodegenerative disease.Recent Advances by In Silico and In Vitro Studies of Amyloid-β 1-42 Fibril Depicted a S-Shape Conformation
P2860
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P2860
Multivariate analyses of amyloid-beta oligomer populations indicate a connection between pore formation and cytotoxicity
description
2012 nî lūn-bûn
@nan
2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Multivariate analyses of amylo ...... ore formation and cytotoxicity
@ast
Multivariate analyses of amylo ...... ore formation and cytotoxicity
@en
Multivariate analyses of amylo ...... ore formation and cytotoxicity
@nl
type
label
Multivariate analyses of amylo ...... ore formation and cytotoxicity
@ast
Multivariate analyses of amylo ...... ore formation and cytotoxicity
@en
Multivariate analyses of amylo ...... ore formation and cytotoxicity
@nl
prefLabel
Multivariate analyses of amylo ...... ore formation and cytotoxicity
@ast
Multivariate analyses of amylo ...... ore formation and cytotoxicity
@en
Multivariate analyses of amylo ...... ore formation and cytotoxicity
@nl
P2860
P50
P1433
P1476
Multivariate analyses of amylo ...... ore formation and cytotoxicity
@en
P2093
Jerry Yang
Panchika Prangkio
P2860
P304
P356
10.1371/JOURNAL.PONE.0047261
P407
P577
2012-10-15T00:00:00Z