TLR5 activation induces secretory interleukin-1 receptor antagonist (sIL-1Ra) and reduces inflammasome-associated tissue damage. - Wikidata - wikimedia - TriplyDB

TLR5 activation induces secretory interleukin-1 receptor antagonist (sIL-1Ra) and reduces inflammasome-associated tissue damage.

TLR5 activation induces secretory interleukin-1 receptor antagonist (sIL-1Ra) and reduces inflammasome-associated tissue damage.

http://www.wikidata.org/entity/Q34451414

about

A mouse model of Salmonella typhi infection Central role of liver in anticancer and radioprotective activities of Toll-like receptor 5 agonist Identification of granulocyte colony-stimulating factor and interleukin-6 as candidate biomarkers of CBLB502 efficacy as a medical radiation countermeasure The Toll-Like Receptor 5 Agonist Entolimod Mitigates Lethal Acute Radiation Syndrome in Non-Human Primates Data on importance of hematopoietic cell derived Lipocalin 2 against gut inflammation.Human trophoblast cells modulate endometrial cells nuclear factor κB response to flagellin in vitro.Transient inability to manage proteobacteria promotes chronic gut inflammation in TLR5-deficient mice.Toll-like receptor 5 (TLR5), IL-1β secretion, and asparagine endopeptidase are critical factors for alveolar macrophage phagocytosis and bacterial killing.Gut feelings of safety: tolerance to the microbiota mediated by innate immune receptors.Cytosolic flagellin receptor NLRC4 protects mice against mucosal and systemic challenges Amino acids 89-96 of Salmonella typhimurium flagellin represent the major domain responsible for TLR5-independent adjuvanticity in the humoral immune response TLR9 is important for protection against intestinal damage and for intestinal repair.Mammalian gut immunity.Toll-like receptor-5 agonist, entolimod, suppresses metastasis and induces immunity by stimulating an NK-dendritic-CD8+ T-cell axis NLRP1 and NLRP3 inflammasomes are essential for distinct outcomes of decreased cytokines but enhanced bacterial killing upon chronic Nod2 stimulation Small intestinal eosinophils regulate Th17 cells by producing IL-1 receptor antagonist.Mechanism of IL-1β modulation of intestinal epithelial barrier involves p38 kinase and activating transcription factor-2 activation Lipocalin 2 alleviates iron toxicity by facilitating hypoferremia of inflammation and limiting catalytic iron generation Genome-wide transcriptional analysis of differentially expressed genes in flagellin-pretreated mouse corneal epithelial cells in response to Pseudomonas aeruginosa: involvement of S100A8/A9.Microbiota-inducible Innate Immune, Siderophore Binding Protein Lipocalin 2 is Critical for Intestinal Homeostasis.Interferon regulatory factor-1 in flagellin-induced reprogramming: potential protective role of CXCL10 in cornea innate defense against Pseudomonas aeruginosa infection.Toll-like receptor-5 agonist Entolimod broadens the therapeutic window of 5-fluorouracil by reducing its toxicity to normal tissues in mice.Therapeutic modulation of microbiota-host metabolic interactions.Innate immune signalling at the intestinal epithelium in homeostasis and disease.Utilizing bacterial flagellins against infectious diseases and cancers.Mucosal barrier injury, fever and infection in neutropenic patients with cancer: introducing the paradigm febrile mucositis.Interaction between gut microbiota and toll-like receptor: from immunity to metabolism TLR5 or NLRC4 is necessary and sufficient for promotion of humoral immunity by flagellin.Neurotensin--regulated miR-133α is involved in proinflammatory signalling in human colonic epithelial cells and in experimental colitis.Mobilan: a recombinant adenovirus carrying Toll-like receptor 5 self-activating cassette for cancer immunotherapy.The Immune System Bridges the Gut Microbiota with Systemic Energy Homeostasis: Focus on TLRs, Mucosal Barrier, and SCFAs.Intein-mediated backbone cyclization of entolimod confers enhanced radioprotective activity in mouse models.

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TLR5 activation induces secretory interleukin-1 receptor antagonist (sIL-1Ra) and reduces inflammasome-associated tissue damage.

http://www.wikidata.org/entity/Q34451414

description

2010 nî lūn-bûn

@nan

2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年学术文章

@wuu

2010年学术文章

@zh-cn

2010年学术文章

@zh-hans

2010年学术文章

@zh-my

2010年学术文章

@zh-sg

2010年學術文章

@yue

name

TLR5 activation induces secret ...... some-associated tissue damage.

@ast

TLR5 activation induces secret ...... some-associated tissue damage.

@en

TLR5 activation induces secretory interleukin-1 receptor antagonist

@nl

type

label

TLR5 activation induces secret ...... some-associated tissue damage.

@ast

TLR5 activation induces secret ...... some-associated tissue damage.

@en

TLR5 activation induces secretory interleukin-1 receptor antagonist

@nl

prefLabel

TLR5 activation induces secret ...... some-associated tissue damage.

@ast

TLR5 activation induces secret ...... some-associated tissue damage.

@en

TLR5 activation induces secretory interleukin-1 receptor antagonist

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Mucosal Immunology

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TLR5 activation induces secret ...... some-associated tissue damage.

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A T Gewirtz

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F A Carvalho

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J D Aitken

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M Vijay-Kumar

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P2860

An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist

Pathogen recognition and innate immunity

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

The balance between IL-1 and IL-1Ra in disease

Expression and release of IL-18 binding protein in response to IFN-gamma

Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression

Interleukin-1 receptor antagonist: role in biology

Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf

Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages

Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5

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102-111

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10.1038/MI.2010.57

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1

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Toll-like receptor

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3012739

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