Cytochrome b5 augments the 17,20-lyase activity of human P450c17 without direct electron transfer.
about
A missense mutation in the human cytochrome b5 gene causes 46,XY disorder of sex development due to true isolated 17,20 lyase deficiencyStructures of cytochrome P450 17A1 with prostate cancer drugs abiraterone and TOK-001Control of androgen biosynthesis in the human through the interaction of Arg347 and Arg358 of CYP17 with cytochrome b5Diversity and function of mutations in p450 oxidoreductase in patients with Antley-Bixler syndrome and disordered steroidogenesisA cytochrome b5 is required for full activity of flavonoid 3', 5'-hydroxylase, a cytochrome P450 involved in the formation of blue flower colorsThe molecular biology, biochemistry, and physiology of human steroidogenesis and its disordersThe syndrome of 17,20 lyase deficiencyWhy boys will be boys: two pathways of fetal testicular androgen biosynthesis are needed for male sexual differentiationRegulation of the adrenal androgen biosynthesisCrystal structures and catalytic mechanism of cytochrome P450 StaP that produces the indolocarbazole skeletonFunctional Zonation of the Adult Mammalian Adrenal CortexRecollection of the early years of the research on cytochrome P450The Role of Protein-Protein and Protein-Membrane Interactions on P450 FunctionProtein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17Mutant P450 oxidoreductase causes disordered steroidogenesis with and without Antley-Bixler syndromeStructures of human steroidogenic cytochrome P450 17A1 with substratesCytochrome P450 17A1 Interactions with the FMN Domain of Its Reductase as Characterized by NMRBackdoor pathway for dihydrotestosterone biosynthesis: implications for normal and abnormal human sex developmentStructural insights into the function of steroidogenic cytochrome P450 17A1The molecular basis of isolated 17,20 lyase deficiencyRegulation of 17,20 lyase activity by cytochrome b5 and by serine phosphorylation of P450c17Role of AMP-activated protein kinase on steroid hormone biosynthesis in adrenal NCI-H295R cellsIdentification of outer mitochondrial membrane cytochrome b5 as a modulator for androgen synthesis in Leydig cellsDeletion of the mouse P450c17 gene causes early embryonic lethalityHuman steroidogenesis: implications for controlled ovarian stimulation with exogenous gonadotropinsHuman cytochrome P450 17A1 conformational selection: modulation by ligand and cytochrome b5.The implication of neuroactive steroids in Tourette's syndrome pathogenesis: A role for 5α-reductase?The steroid metabolome of adrenarcheDevelopment and function of the human fetal adrenal cortex: a key component in the feto-placental unit.Human cytochrome p450c17: single step purification and phosphorylation of serine 258 by protein kinase a.Androgenic potential of human fetal adrenals at the end of the first trimester.Role of protein-protein interactions in cytochrome P450-mediated drug metabolism and toxicityIntra-adrenal regulation of androgen synthesis.Adrenarche - physiology, biochemistry and human disease.Allosteric phenomena in cytochrome P450-catalyzed monooxygenations.The hunt for a selective 17,20 lyase inhibitor; learning lessons from nature.Recent Structural Insights into Cytochrome P450 Function.Placental estrogen suppresses cyclin D1 expression in the nonhuman primate fetal adrenal cortex3βHSD and CYB5A double positive adrenocortical cells during adrenal development/agingCortisol stimulates secretion of dehydroepiandrosterone in human adrenocortical cells through inhibition of 3betaHSD2.
P2860
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P2860
Cytochrome b5 augments the 17,20-lyase activity of human P450c17 without direct electron transfer.
description
1998 nî lūn-bûn
@nan
1998 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Cytochrome b5 augments the 17, ...... hout direct electron transfer.
@ast
Cytochrome b5 augments the 17, ...... hout direct electron transfer.
@en
Cytochrome b5 augments the 17, ...... hout direct electron transfer.
@nl
type
label
Cytochrome b5 augments the 17, ...... hout direct electron transfer.
@ast
Cytochrome b5 augments the 17, ...... hout direct electron transfer.
@en
Cytochrome b5 augments the 17, ...... hout direct electron transfer.
@nl
prefLabel
Cytochrome b5 augments the 17, ...... hout direct electron transfer.
@ast
Cytochrome b5 augments the 17, ...... hout direct electron transfer.
@en
Cytochrome b5 augments the 17, ...... hout direct electron transfer.
@nl
P2093
P2860
P356
P1476
Cytochrome b5 augments the 17, ...... hout direct electron transfer.
@en
P2093
P2860
P304
P356
10.1074/JBC.273.6.3158
P407
P577
1998-02-01T00:00:00Z