Adenylate cyclase 6 determines cAMP formation and aquaporin-2 phosphorylation and trafficking in inner medulla.
about
Cardiac-specific overexpression of caveolin-3 attenuates cardiac hypertrophy and increases natriuretic peptide expression and signalingRole of guanine-nucleotide exchange factor Epac in renal physiology and pathophysiologyRegulation of nephron water and electrolyte transport by adenylyl cyclasesAdenylyl cyclase 6 enhances NKCC2 expression and mediates vasopressin-induced phosphorylation of NKCC2 and NCCRenal phosphate wasting in the absence of adenylyl cyclase 6Tolvaptan plus pasireotide shows enhanced efficacy in a PKD1 modelIsoform selectivity of adenylyl cyclase inhibitors: characterization of known and novel compoundsStimulation of renin secretion by catecholamines is dependent on adenylyl cyclases 5 and 6.Expression of a dominant negative PKA mutation in the kidney elicits a diabetes insipidus phenotypeRegulation of renal NaCl and water transport by the ATP/UTP/P2Y2 receptor systemCollecting duct-specific knockout of adenylyl cyclase type VI causes a urinary concentration defect in mice.Chloride secretion by renal collecting ductsNatriuretic effect by exendin-4, but not the DPP-4 inhibitor alogliptin, is mediated via the GLP-1 receptor and preserved in obese type 2 diabetic mice.P2Y receptors and kidney function.Regulation of intestinal SGLT1 by catestatin in hyperleptinemic type 2 diabetic mice.Calmodulin-sensitive adenylyl cyclases mediate AVP-dependent cAMP production and Cl- secretion by human autosomal dominant polycystic kidney cells.Regulation of aquaporin-2 in the kidney: A molecular mechanism of body-water homeostasis.Knockout of Na-glucose transporter SGLT2 attenuates hyperglycemia and glomerular hyperfiltration but not kidney growth or injury in diabetes mellitusAdenylyl cyclase VI mediates vasopressin-stimulated ENaC activity.AKAP220 manages apical actin networks that coordinate aquaporin-2 location and renal water reabsorption.Adenylyl cyclase 6 deficiency ameliorates polycystic kidney disease.Lack of an effect of collecting duct-specific deletion of adenylyl cyclase 3 on renal Na+ and water excretion or arterial pressure.Adenylyl cyclase 4 does not regulate collecting duct water and sodium handlingRole of adenylyl cyclase 6 in the development of lithium-induced nephrogenic diabetes insipidus.In vivo and ex vivo analysis of tubule function.Localization and function of the renal calcium-sensing receptor.Vasopressin regulation of sodium transport in the distal nephron and collecting duct.The vasopressin type 2 receptor and prostaglandin receptors EP2 and EP4 can increase aquaporin-2 plasma membrane targeting through a cAMP-independent pathway.The V2 receptor antagonist tolvaptan raises cytosolic calcium and prevents AQP2 trafficking and function: an in vitro and in vivo assessmentMolecular mechanisms regulating aquaporin-2 in kidney collecting duct.Outside the mainstream: novel collecting duct proteins regulating water balance.New Insights into the Molecular Mechanisms Targeting Tubular Channels/Transporters in PKD Development.Aquaporin-2 membrane targeting: still a conundrum.International Union of Basic and Clinical Pharmacology. CI. Structures and Small Molecule Modulators of Mammalian Adenylyl Cyclases.Lack of an effect of nephron-specific deletion of adenylyl cyclase 3 on renal sodium and water excretion or arterial pressure.Prostaglandin-E2 Mediated Increase in Calcium and Phosphate Excretion in a Mouse Model of Distal Nephron Salt WastingConnecting type A intercalated cell metabolic state to V-ATPase function: phosphorylation does matter!Renal tubular NHE3 is required in the maintenance of water and sodium chloride homeostasis.Caveolin 1 Promotes Renal Water and Salt Reabsorption.Vasopressin lowers renal epoxyeicosatrienoic acid levels by activating soluble epoxide hydrolase.
P2860
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P2860
Adenylate cyclase 6 determines cAMP formation and aquaporin-2 phosphorylation and trafficking in inner medulla.
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Adenylate cyclase 6 determines ...... trafficking in inner medulla.
@ast
Adenylate cyclase 6 determines ...... trafficking in inner medulla.
@en
Adenylate cyclase 6 determines ...... trafficking in inner medulla.
@nl
type
label
Adenylate cyclase 6 determines ...... trafficking in inner medulla.
@ast
Adenylate cyclase 6 determines ...... trafficking in inner medulla.
@en
Adenylate cyclase 6 determines ...... trafficking in inner medulla.
@nl
prefLabel
Adenylate cyclase 6 determines ...... trafficking in inner medulla.
@ast
Adenylate cyclase 6 determines ...... trafficking in inner medulla.
@en
Adenylate cyclase 6 determines ...... trafficking in inner medulla.
@nl
P2093
P2860
P50
P356
P1476
Adenylate cyclase 6 determines ...... trafficking in inner medulla.
@en
P2093
H Kirk Hammond
Jana Schroth
Paul A Insel
Volker Vallon
P2860
P304
P356
10.1681/ASN.2010040409
P577
2010-09-23T00:00:00Z