Epoxidation of olefins by cytochrome P450: evidence from site-specific mutagenesis for hydroperoxo-iron as an electrophilic oxidant.
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Structures of human cytochrome P-450 2E1. Insights into the binding of inhibitors and both small molecular weight and fatty acid substratesCarbocations in the synthesis of prostaglandins by the cyclooxygenase of PGH synthase? A radical departure!Structure of Cytochrome P450 PimD Suggests Epoxidation of the Polyene Macrolide Pimaricin Occurs via a Hydroperoxoferric IntermediateVariations on a (t)heme--novel mechanisms, redox partners and catalytic functions in the cytochrome P450 superfamilyMechanistic aspects of CYP74 allene oxide synthases and related cytochrome P450 enzymesApplication of microorganisms towards synthesis of chiral terpenoid derivatives.The structural basis for substrate anchoring, active site selectivity, and product formation by P450 PikC from Streptomyces venezuelae.Kinetics of oxidation of benzphetamine by compounds I of cytochrome P450 2B4 and its mutants.Coupling and uncoupling mechanisms in the methoxythreonine mutant of cytochrome P450cam: a quantum mechanical/molecular mechanical study.Oxidation reactions performed by soluble methane monooxygenase hydroxylase intermediates H(peroxo) and Q proceed by distinct mechanismsEnzyme ingenuity in biological oxidations: a trail leading to cytochrome p450.N-oxidative transformation of free and N-substituted amine functions by cytochrome P450 as means of bioactivation and detoxication.Electron supply and catalytic oxidation of nitrogen by cytochrome P450 and nitric oxide synthase.The bioinorganic chemistry of iron in oxygenases and supramolecular assemblies.Insight into the mechanism of aromatic hydroxylation by toluene 4-monooxygenase by use of specifically deuterated toluene and p-xylene.New insights into the structural characteristics and functional relevance of the human cytochrome P450 2D6 enzyme.Differences and comparisons of the properties and reactivities of iron(III)-hydroperoxo complexes with saturated coordination sphereIncreases in plasma trans-EETs and blood pressure reduction in spontaneously hypertensive rats.Altered spin state equilibrium in the T309V mutant of cytochrome P450 2D6: a spectroscopic and computational study.Models and mechanisms of O-O bond activation by cytochrome P450. A critical assessment of the potential role of multiple active intermediates in oxidative catalysis.Cytochrome P450-type hydroxylation and epoxidation in a tyrosine-liganded hemoprotein, catalase-related allene oxide synthase.The use of deuterated camphor as a substrate in (1)H ENDOR studies of hydroxylation by cryoreduced oxy P450cam provides new evidence of the involvement of compound IReactivity patterns of cytochrome P450 enzymes: multifunctionality of the active species, and the two states-two oxidants conundrum.About oxygen, cytochrome p450 and titanium: learning from Ron Estabrook.Mechanism of and exquisite selectivity for O-O bond formation by the heme-dependent chlorite dismutaseOxygen activation by cytochrome P450 monooxygenaseVitamin C activation of the biosynthesis of epoxyeicosatrienoic acids.Resonance Raman spectroscopy of the oxygenated intermediates of human CYP19A1 implicates a compound i intermediate in the final lyase step.Diversity of P450 enzymes in the biosynthesis of natural productsThe active site of the thermophilic CYP119 from Sulfolobus solfataricus.Enzymatic and free radical formation of cis- and trans- epoxyeicosatrienoic acids in vitro and in vivo.Spectroscopic studies of the cytochrome P450 reaction mechanisms.Spectroscopic and Kinetic Evidence for the Crucial Role of Compound 0 in the P450cam -Catalyzed Hydroxylation of Camphor by Hydrogen Peroxide.Products from enzyme-catalyzed oxidations of norcarenes.Desaturase reactions complicate the use of norcarane as a mechanistic probe. Unraveling the mixture of twenty-plus products formed in enzyme-catalyzed oxidations of norcarane.Investigation of the role of cytochrome P450 2B4 active site residues in substrate metabolism based on crystal structures of the ligand-bound enzymeEpoxidation activities of human cytochromes P450c17 and P450c21.Radical intermediates in monooxygenase reactions of rieske dioxygenases.Cytochrome P450/NADPH-dependent biosynthesis of 5,6-trans-epoxyeicosatrienoic acid from 5,6-trans-arachidonic acid.Monooxygenation by a thermophilic cytochrome P450 via direct electron donation from NADH.
P2860
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P2860
Epoxidation of olefins by cytochrome P450: evidence from site-specific mutagenesis for hydroperoxo-iron as an electrophilic oxidant.
description
1998 nî lūn-bûn
@nan
1998 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մարտին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Epoxidation of olefins by cyto ...... n as an electrophilic oxidant.
@ast
Epoxidation of olefins by cyto ...... n as an electrophilic oxidant.
@en
Epoxidation of olefins by cyto ...... n as an electrophilic oxidant.
@nl
type
label
Epoxidation of olefins by cyto ...... n as an electrophilic oxidant.
@ast
Epoxidation of olefins by cyto ...... n as an electrophilic oxidant.
@en
Epoxidation of olefins by cyto ...... n as an electrophilic oxidant.
@nl
prefLabel
Epoxidation of olefins by cyto ...... n as an electrophilic oxidant.
@ast
Epoxidation of olefins by cyto ...... n as an electrophilic oxidant.
@en
Epoxidation of olefins by cyto ...... n as an electrophilic oxidant.
@nl
P2093
P2860
P356
P1476
Epoxidation of olefins by cyto ...... n as an electrophilic oxidant.
@en
P2093
P2860
P304
P356
10.1073/PNAS.95.7.3555
P407
P577
1998-03-01T00:00:00Z