Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies. - Wikidata - wikimedia - TriplyDB

Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies.

Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies.

http://www.wikidata.org/entity/Q34463167

about

Genetic perspective on the role of the autophagy-lysosome pathway in Parkinson disease Genetics Underlying Atypical Parkinsonism and Related Neurodegenerative Disorders Arguing against the proposed definition changes of PD Alpha-synuclein and tau: teammates in neurodegeneration?LIMP-2 expression is critical for β-glucocerebrosidase activity and α-synuclein clearance Parkinson Disease and Dementia.Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death.Lewy body dementias.The Broad Impact of TOM40 on Neurodegenerative Diseases in Aging Genome-wide association study of neocortical Lewy-related pathology.A cytosine-thymine (CT)-rich haplotype in intron 4 of SNCA confers risk for Lewy body pathology in Alzheimer's disease and affects SNCA expression.Role for the microtubule-associated protein tau variant p.A152T in risk of α-synucleinopathies.Mitochondrial targeting sequence variants of the CHCHD2 gene are a risk for Lewy body disorders A rapid and cost-effective method for genotyping apolipoprotein E gene polymorphism.Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Parkinson's and Alzheimer's diseases.Characterization of the complex formed by β-glucocerebrosidase and the lysosomal integral membrane protein type-2.SCARB2 variants and glucocerebrosidase activity in Parkinson's disease.A Personalized Approach to Parkinson's Disease Patients Based on Founder Mutation Analysis Exome sequencing in dementia with Lewy bodies Associations between APOE polymorphisms and seven diseases with cognitive impairment including Alzheimer's disease, frontotemporal dementia, and dementia with Lewy bodies in southeast China Up-regulation of SNCA gene expression: implications to synucleinopathies TREM2 p.R47H substitution is not associated with dementia with Lewy bodies.Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease.Epigenetic considerations of the APOE gene. [corrected].Large-scale exploratory genetic analysis of cognitive impairment in Parkinson's disease.Genetic susceptibility variants in parkinsonism.Parkinson's disease: acid-glucocerebrosidase activity and alpha-synuclein clearance.Concomitant AD pathology affects clinical manifestation and survival in dementia with Lewy bodies.Disorders of lysosomal acidification-The emerging role of v-ATPase in aging and neurodegenerative disease.Metals in Alzheimer's and Parkinson's Disease: Relevance to Dementia with Lewy Bodies.Impulse control disorder, lysosomal malfunction and ATP13A2 insufficiency in Parkinsonism.Biomarker-driven phenotyping in Parkinson's disease: A translational missing link in disease-modifying clinical trials.Structural variants in SNCA gene and the implication to synucleinopathies.Lewy Body Disorders.A clinicopathological approach to the diagnosis of dementia.α-synuclein genetic variability: A biomarker for dementia in Parkinson disease.Copy number variation analysis of the 17q21.31 region and its role in neurodegenerative diseases.Cortical Lewy bodies and Aβ burden are associated with prevalence and timing of dementia in Lewy body diseases.Parkinson's Disease Genetic Loci in Rapid Eye Movement Sleep Behavior Disorder.Current concepts and controversies in the pathogenesis of Parkinson's disease dementia and Dementia with Lewy Bodies.

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P2860

Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies.

http://www.wikidata.org/entity/Q34463167

description

2014 nî lūn-bûn

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2014 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2014 թվականի հունիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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name

Genetic analysis implicates AP ...... of dementia with Lewy bodies.

@ast

Genetic analysis implicates AP ...... of dementia with Lewy bodies.

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Genetic analysis implicates AP ...... of dementia with Lewy bodies.

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Genetic analysis implicates AP ...... of dementia with Lewy bodies.

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Genetic analysis implicates AP ...... of dementia with Lewy bodies.

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Genetic analysis implicates AP ...... of dementia with Lewy bodies.

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type

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Genetic analysis implicates AP ...... of dementia with Lewy bodies.

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Genetic analysis implicates AP ...... of dementia with Lewy bodies.

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Genetic analysis implicates AP ...... of dementia with Lewy bodies.

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Genetic analysis implicates AP ...... of dementia with Lewy bodies.

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Genetic analysis implicates AP ...... of dementia with Lewy bodies.

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Genetic analysis implicates AP ...... of dementia with Lewy bodies.

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prefLabel

Genetic analysis implicates AP ...... of dementia with Lewy bodies.

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Genetic analysis implicates AP ...... of dementia with Lewy bodies.

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Genetic analysis implicates AP ...... of dementia with Lewy bodies.

@de

Genetic analysis implicates AP ...... of dementia with Lewy bodies.

@en

Genetic analysis implicates AP ...... of dementia with Lewy bodies.

@fr

Genetic analysis implicates AP ...... of dementia with Lewy bodies.

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Human Molecular Genetics

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Genetic analysis implicates AP ...... of dementia with Lewy bodies.

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Afina Lemstra

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Anne Braae

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David Mann

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Dena G Hernandez

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Dennis W Dickson

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Imelda Barber

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Karen Marder

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Kristelle Brown

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Laura Parkkinen

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Lawrence S Honig

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P2860

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease.

Genome-wide association study reveals genetic risk underlying Parkinson's disease

PLINK: a tool set for whole-genome association and population-based linkage analyses

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

Best practices and joint calling of the HumanExome BeadChip: the CHARGE Consortium.

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10.1093/HMG/DDU334

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23

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23

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Philip Scheltens

Stuart Pickering-Brown

Ekaterina Rogaeva

Glenda Halliday

Andrew John Lees

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2014-06-27T00:00:00Z

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264633156

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