Disruption of the regulatory beta subunit of protein kinase CK2 in mice leads to a cell-autonomous defect and early embryonic lethality
about
Casein kinase 2beta as a novel enhancer of activin-like receptor-1 signalingCK2 phosphorylation of eukaryotic translation initiation factor 5 potentiates cell cycle progressionCasein kinase 2-dependent serine phosphorylation of MuSK regulates acetylcholine receptor aggregation at the neuromuscular junctionCK2 is responsible for phosphorylation of human La protein serine-366 and can modulate rpL37 5'-terminal oligopyrimidine mRNA metabolismThe multiple personalities of the regulatory subunit of protein kinase CK2: CK2 dependent and CK2 independent roles reveal a secret identity for CK2beta.Protein Kinase CK2: A Targetable BCR-ABL Partner in Philadelphia Positive LeukemiasThe interaction of CK2α and CK2β, the subunits of protein kinase CK2, requires CK2β in a preformed conformation and is enthalpically drivenPotent and Selective Inhibitors of CK2 Kinase Identified through Structure-Guided HybridizationDifferential phosphorylation of a regulatory subunit of protein kinase CK2 by target of rapamycin complex 1 signaling and the Cdc-like kinase Kns1.Involvement of Plasmodium falciparum protein kinase CK2 in the chromatin assembly pathwayPhosphorylation of the regulatory beta-subunit of protein kinase CK2 by checkpoint kinase Chk1: identification of the in vitro CK2beta phosphorylation siteDisruption of CK2beta in embryonic neural stem cells compromises proliferation and oligodendrogenesis in the mouse telencephalonCAF-1 is essential for heterochromatin organization in pluripotent embryonic cellsTenfibgen ligand nanoencapsulation delivers bi-functional anti-CK2 RNAi oligomer to key sites for prostate cancer targeting using human xenograft tumors in miceComparative phosphoproteomic analysis of neonatal and adult murine brainEnhancing chemosensitivity to gemcitabine via RNA interference targeting the catalytic subunits of protein kinase CK2 in human pancreatic cancer cellsA homozygous mutant embryonic stem cell bank applicable for phenotype-driven genetic screening.Impact of protein kinase CK2 inhibitors on proliferation and differentiation of neural stem cells.Inhibition of casein kinase 2 blocks G2/M transition in early embryo mitosis but not in oocyte meiosis in mouseOverexpression of nuclear protein kinase CK2 α catalytic subunit (CK2α) as a poor prognosticator in human colorectal cancer.IL-6 stabilizes Twist and enhances tumor cell motility in head and neck cancer cells through activation of casein kinase 2.Emergence of protein kinase CK2 as a key target in cancer therapyProtein kinase CK2: a new view of an old molecular complexTherapeutic CK2 inhibition attenuates diverse prosurvival signaling cascades and decreases cell viability in human breast cancer cells.Inhibition of CK2α down-regulates Hedgehog/Gli signaling leading to a reduction of a stem-like side population in human lung cancer cellsProtein kinase CK2α is overexpressed in colorectal cancer and modulates cell proliferation and invasion via regulating EMT-related genesA CK2-dependent mechanism for activation of the JAK-STAT signaling pathway.Protein kinase CK2 in health and disease: CK2: a key player in cancer biologyTenfibgen-DMAT Nanocapsule Delivers CK2 Inhibitor DMAT to Prostate Cancer Xenograft Tumors Causing Inhibition of Cell Proliferation.Nanoencapsulated anti-CK2 small molecule drug or siRNA specifically targets malignant cancer but not benign cellsFoxk1 recruits the Sds3 complex and represses gene expression in myogenic progenitors.Order or chaos? An evaluation of the regulation of protein kinase CK2.Threonine 393 of beta-catenin regulates interaction with Axin.The human embryonic stem cell proteome revealed by multidimensional fractionation followed by tandem mass spectrometryThe alpha catalytic subunit of protein kinase CK2 is required for mouse embryonic developmentProtein kinase CK2 modulates developmental functions of the abscisic acid responsive protein Rab17 from maize.CK2beta gene silencing increases cell susceptibility to influenza A virus infection resulting in accelerated virus entry and higher viral protein content.Two distinct phosphorylation events govern the function of muscle FHOD3.Protein kinase CK2--a key suppressor of apoptosis.CK2α is essential for embryonic morphogenesis.
P2860
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P2860
Disruption of the regulatory beta subunit of protein kinase CK2 in mice leads to a cell-autonomous defect and early embryonic lethality
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Disruption of the regulatory b ...... and early embryonic lethality
@ast
Disruption of the regulatory b ...... and early embryonic lethality
@en
Disruption of the regulatory b ...... and early embryonic lethality
@nl
type
label
Disruption of the regulatory b ...... and early embryonic lethality
@ast
Disruption of the regulatory b ...... and early embryonic lethality
@en
Disruption of the regulatory b ...... and early embryonic lethality
@nl
prefLabel
Disruption of the regulatory b ...... and early embryonic lethality
@ast
Disruption of the regulatory b ...... and early embryonic lethality
@en
Disruption of the regulatory b ...... and early embryonic lethality
@nl
P2093
P2860
P1476
Disruption of the regulatory b ...... and early embryonic lethality
@en
P2093
Brigitte Boldyreff
Hans H Jensen
Hervé Pointu
Muriel Vernet
Olaf-Georg Issinger
Olivier Blond
Thierry Buchou
P2860
P304
P356
10.1128/MCB.23.3.908-915.2003
P407
P577
2003-02-01T00:00:00Z