Targeted disruption of the mouse Mel(1b) melatonin receptor. - Wikidata - wikimedia - TriplyDB

Targeted disruption of the mouse Mel(1b) melatonin receptor.

Targeted disruption of the mouse Mel(1b) melatonin receptor.

http://www.wikidata.org/entity/Q34463520

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International Union of Basic and Clinical Pharmacology. LXXV. Nomenclature, classification, and pharmacology of G protein-coupled melatonin receptors.Evaluation of the efficacy and safety of ramelteon in subjects with chronic insomnia Tre1, a G protein-coupled receptor, directs transepithelial migration of Drosophila germ cells MT1 and MT2 Melatonin Receptors: A Therapeutic Perspective Synthesis and functional characterization of substituted isoquinolinones as MT2-selective melatoninergic ligands Melatonin influences insulin secretion primarily via MT(1) receptors in rat insulinoma cells (INS-1) and mouse pancreatic islets Genetic suppression of the circadian Clock mutation by the melatonin biosynthesis pathway Parent-of-origin effects in autism identified through genome-wide linkage analysis of 16,000 SNPs.Pharmacology of ramelteon, a selective MT1/MT2 receptor agonist: a novel therapeutic drug for sleep disorders MTNR1B G24E variant associates With BMI and fasting plasma glucose in the general population in studies of 22,142 Europeans Effects of the melatonin MT-1/MT-2 agonist ramelteon on daytime body temperature and sleep.Understanding melatonin receptor pharmacology: latest insights from mouse models, and their relevance to human disease.Piromelatine exerts antinociceptive effect via melatonin, opioid, and 5HT1A receptors and hypnotic effect via melatonin receptors in a mouse model of neuropathic pain.Regulation of bone mass through pineal-derived melatonin-MT2 receptor pathway.Melatonin and its receptors: a new class of sleep-promoting agents.Melatonin-receptor-1-deficiency affects neurogenic differentiation factor immunoreaction in pancreatic islets and enteroendocrine cells of mice.The circadian system and melatonin: lessons from rats and mice.Melatonin administration alters nicotine preference consumption via signaling through high-affinity melatonin receptors.Melatonin Entrains PER2::LUC Bioluminescence Circadian Rhythm in the Mouse Cornea.Circadian Rhythm Regulates Development of Enamel in Mouse Mandibular First Molar.Genetic tests of biologic systems in affective disorders.Diurnal variation in nicotine sensitivity in mice: role of genetic background and melatonin.Just the two of us: melatonin and adenosine in rodent pituitary function.Genetic deletion of the MT1 or MT2 melatonin receptors abrogates methamphetamine-induced reward in C3H/HeN mice.Prophylactic melatonin significantly reduces Alzheimer's neuropathology and associated cognitive deficits independent of antioxidant pathways in AβPP(swe)/PS1 mice.Therapeutic potential of melatonin ligands.Neurobiology of the sleep-wake cycle: sleep architecture, circadian regulation, and regulatory feedback.Melatonin receptors, heterodimerization, signal transduction and binding sites: what's new?Melatonin and pancreatic islets: interrelationships between melatonin, insulin and glucagon Pharmacotherapy of insomnia with ramelteon: safety, efficacy and clinical applications Does a melatonin-dependent circadian oscillator in the pars tuberalis drive prolactin seasonal rhythmicity?Npas4 is activated by melatonin, and drives the clock gene Cry1 in the ovine pars tuberalis.Mu- and kappa-opioids induce the differentiation of embryonic stem cells to neural progenitors.Genetics of circadian rhythms in Mammalian model organisms.Efficacy and safety of 6-month nightly ramelteon administration in adults with chronic primary insomnia A molecular and chemical perspective in defining melatonin receptor subtype selectivity.New approaches in the management of insomnia: weighing the advantages of prolonged-release melatonin and synthetic melatoninergic agonists.Microtubules modulate melatonin receptors involved in phase-shifting circadian activity rhythms: in vitro and in vivo evidence.Unveiling the role of melatonin MT2 receptors in sleep, anxiety and other neuropsychiatric diseases: a novel target in psychopharmacology.The end of a myth: cloning and characterization of the ovine melatonin MT(2) receptor.

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P2860

Targeted disruption of the mouse Mel(1b) melatonin receptor.

http://www.wikidata.org/entity/Q34463520

description

2003 nî lūn-bûn

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2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2003 թվականի փետրվարին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

Targeted disruption of the mouse Mel

@nl

Targeted disruption of the mouse Mel(1b) melatonin receptor.

@ast

Targeted disruption of the mouse Mel(1b) melatonin receptor.

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type

label

Targeted disruption of the mouse Mel

@nl

Targeted disruption of the mouse Mel(1b) melatonin receptor.

@ast

Targeted disruption of the mouse Mel(1b) melatonin receptor.

@en

prefLabel

Targeted disruption of the mouse Mel

@nl

Targeted disruption of the mouse Mel(1b) melatonin receptor.

@ast

Targeted disruption of the mouse Mel(1b) melatonin receptor.

@en

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MCB.23.3.1054-1060.2003

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Molecular and Cellular Biology

P1476

Targeted disruption of the mouse Mel(1b) melatonin receptor.

@en

P2093

Charlotte von Gall

http://www.w3.org/2001/XMLSchema#string

David R Weaver

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Jorg H Stehle

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Rick L Pieschl

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Steven M Reppert

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Valentin K Gribkoff

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Xiaowei Jin

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P2860

Molecular characterization of a second melatonin receptor expressed in human retina and brain: the Mel1b melatonin receptor

Cloning of a melatonin-related receptor from human pituitary

Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Nature's knockout: the Mel1b receptor is not necessary for reproductive and circadian responses to melatonin in Siberian hamsters

Melatonin receptors step into the light: cloning and classification of subtypes

Genetic control of melatonin synthesis in the pineal gland of the mouse

Activation of MT(2) melatonin receptors in rat suprachiasmatic nucleus phase advances the circadian clock.

Tissue-specific abolition of Per1 expression in the pars tuberalis by pinealectomy in the Syrian hamster.

Bimodal regulation of mPeriod promoters by CREB-dependent signaling and CLOCK/BMAL1 activity.

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1054-1060

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10.1128/MCB.23.3.1054-1060.2003

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