Systematic mutagenesis of the Saccharomyces cerevisiae MLH1 gene reveals distinct roles for Mlh1p in meiotic crossing over and in vegetative and meiotic mismatch repair
about
The RecQ DNA helicases in DNA repairFunctional residues on the surface of the N-terminal domain of yeast Pms1Sustained and rapid chromosome movements are critical for chromosome pairing and meiotic progression in budding yeast.A role for the MutL homologue MLH2 in controlling heteroduplex formation and in regulating between two different crossover pathways in budding yeast.Csm4, in collaboration with Ndj1, mediates telomere-led chromosome dynamics and recombination during yeast meiosis.Genetic analysis of mlh3 mutations reveals interactions between crossover promoting factors during meiosis in baker's yeast.Role of proliferating cell nuclear antigen interactions in the mismatch repair-dependent processing of mitotic and meiotic recombination intermediates in yeast.Identification and dissection of a complex DNA repair sensitivity phenotype in Baker's yeast.Variation in crossover frequencies perturb crossover assurance without affecting meiotic chromosome segregation in Saccharomyces cerevisiaeGenetic instability in budding and fission yeast-sources and mechanismsHuman MutL homolog (MLH1) function in DNA mismatch repair: a prospective screen for missense mutations in the ATPase domain.Two levels of interference in mouse meiotic recombinationIncompatibilities involving yeast mismatch repair genes: a role for genetic modifiers and implications for disease penetrance and variation in genomic mutation rates.The pch2Delta mutation in baker's yeast alters meiotic crossover levels and confers a defect in crossover interference.Modulating Crossover Frequency and Interference for Obligate Crossovers in Saccharomyces cerevisiae Meiosis.Genetic analysis of baker's yeast Msh4-Msh5 reveals a threshold crossover level for meiotic viability.Recombination proteins mediate meiotic spatial chromosome organization and pairing.Combined fluorescent and electron microscopic imaging unveils the specific properties of two classes of meiotic crossovers.Negative epistasis between natural variants of the Saccharomyces cerevisiae MLH1 and PMS1 genes results in a defect in mismatch repair.Reduced meiotic crossovers and delayed prophase I progression in AtMLH3-deficient Arabidopsis.Competing crossover pathways act during meiosis in Saccharomyces cerevisiaeMLH1 mutations differentially affect meiotic functions in Saccharomyces cerevisiaeAccumulation of recessive lethal mutations in Saccharomyces cerevisiae mlh1 mismatch repair mutants is not associated with gross chromosomal rearrangements.Mismatch repair system in endometriotic tissue and eutopic endometrium of unaffected womenMeiotic recombination intermediates and mismatch repair proteins.Mismatch repair-dependent mutagenesis in nondividing cells.The unstructured linker arms of Mlh1-Pms1 are important for interactions with DNA during mismatch repair.Distinct DNA-binding surfaces in the ATPase and linker domains of MutLγ determine its substrate specificities and exert separable functions in meiotic recombination and mismatch repairNon-canonical actions of mismatch repairRoles for mismatch repair family proteins in promoting meiotic crossing over.A mutation in the putative MLH3 endonuclease domain confers a defect in both mismatch repair and meiosis in Saccharomyces cerevisiae.Characterization of a highly conserved binding site of Mlh1 required for exonuclease I-dependent mismatch repair.Crossover patterning by the beam-film model: analysis and implications.Structure of the MutL C-terminal domain: a model of intact MutL and its roles in mismatch repairR.I.P. to the PIP: PCNA-binding motif no longer considered specific: PIP motifs and other related sequences are not distinct entities and can bind multiple proteins involved in genome maintenance.mlh3 mutations in baker's yeast alter meiotic recombination outcomes by increasing noncrossover events genome-wide.Pseudomonas aeruginosa MutL protein functions in Escherichia coli.Mismatch repair outside of replication.Analysis of crossover breakpoints yields new insights into the nature of the gene conversion events associated with large NF1 deletions mediated by nonallelic homologous recombination.Mismatch Repair Incompatibilities in Diverse Yeast Populations.
P2860
Q24561510-69FDF9E5-6B29-4DAC-B4A5-3B6C8CF50E2BQ27659620-7CD34C71-EC37-43EB-9D9B-6ECB960406CEQ27929908-F902BB4D-9854-4B4A-9F85-1959F6FA8AAEQ27931208-A2AF0FC4-774C-4294-83DD-FA81A51C4609Q27931634-B8B0F922-E0D8-4C50-AD68-4F39B38EBA17Q27932384-A40CAEE0-C65D-4CB3-BF59-5B8A95B17819Q27938184-8734F1C0-7DBE-4027-B60C-99935DD73107Q27940380-E7A64D08-F026-4426-8B59-04B3B7D46AF0Q28253087-B48761A5-69E5-4B50-9D38-5ABDD86FF611Q28264035-E5018B23-6B26-480E-8189-7A914A189E33Q31119964-E423B571-05B8-4D88-9AE5-00952AAC62C7Q33246417-5491C180-D936-4A37-A9CD-89CF3ECF04FEQ33345237-84FCC6D8-DA10-4E5F-A810-85466A332562Q33486516-C306C196-1AEB-4A51-AB1D-D55F50B82631Q33667402-2084309B-5AE0-46EB-A0B6-3732B8C2ED9EQ33701780-043D6311-1236-4AA2-BCE4-36D58FC68E03Q33777134-E41D522F-EAF7-42F5-9599-C3BB580EBDCFQ34218228-A1B3A07B-8FFA-44E1-BED0-56F329961777Q34480201-3AD992EC-C7BC-47A5-9401-74443F413C8CQ34500851-35F23428-C30C-454A-8514-31E3BCA7DEF9Q34569381-C267F248-16DD-4179-AFA1-AE3B1B0BDBD8Q34617068-C1381389-DAB8-439C-B6F5-939BC3AD63E1Q35038676-6B1C18B8-8B61-4492-85B9-758702DEBB36Q35406659-417473FF-F1EF-4354-8171-9336A0C1A50DQ35910256-8E2FF48E-6565-4E48-982C-E89C9ABEA5E4Q35924951-4648568D-5379-4ED8-A0C0-FBBF32E704B7Q36162012-6E42D4DA-49A2-4B36-BD17-0CEF087F0C2DQ36371989-04EE36F6-903F-465C-8BF1-F9C5235E6BFFQ36540667-6498F52B-0A36-4B16-B72A-2180D9B5F30AQ36540776-26754CE5-4CD1-4A44-9669-36D3B16A0CC2Q36724317-103638C6-A324-405C-B516-DAD73F0E0094Q37072156-8068E6F8-2EE4-49AB-BC88-D8348EE5CBFDQ37533767-FD481010-8F8B-4019-9E6A-DD0921F375E8Q37592729-A4C780AF-13A3-478B-89AB-1A0844114241Q38931497-44119E52-4582-494C-8997-5CEF994AFEF1Q42352313-D9861FE7-EED0-49A3-9C25-906EE80542C9Q42932258-4C9ABBE0-CC36-4963-88FB-269C1EEED249Q43241493-6222994E-97E4-4C6A-BC19-5364CD3241EEQ44780934-3C873A2C-9415-413C-AEA0-5071518B350FQ48244295-AC956E0D-9F20-4E57-95A1-17D26664A551
P2860
Systematic mutagenesis of the Saccharomyces cerevisiae MLH1 gene reveals distinct roles for Mlh1p in meiotic crossing over and in vegetative and meiotic mismatch repair
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Systematic mutagenesis of the ...... ve and meiotic mismatch repair
@ast
Systematic mutagenesis of the ...... ve and meiotic mismatch repair
@en
Systematic mutagenesis of the ...... ve and meiotic mismatch repair
@nl
type
label
Systematic mutagenesis of the ...... ve and meiotic mismatch repair
@ast
Systematic mutagenesis of the ...... ve and meiotic mismatch repair
@en
Systematic mutagenesis of the ...... ve and meiotic mismatch repair
@nl
prefLabel
Systematic mutagenesis of the ...... ve and meiotic mismatch repair
@ast
Systematic mutagenesis of the ...... ve and meiotic mismatch repair
@en
Systematic mutagenesis of the ...... ve and meiotic mismatch repair
@nl
P2093
P2860
P1476
Systematic mutagenesis of the ...... ve and meiotic mismatch repair
@en
P2093
Amanda Wraith Kijas
Eric Alani
Julie Heck
Marc Waase
Sumeet Sarin
P2860
P304
P356
10.1128/MCB.23.3.873-886.2003
P407
P577
2003-02-01T00:00:00Z