Pentylindole/Pentylindazole Synthetic Cannabinoids and Their 5-Fluoro Analogs Produce Different Primary Metabolites: Metabolite Profiling for AB-PINACA and 5F-AB-PINACA
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Approaches, Challenges, and Advances in Metabolism of New Synthetic Cannabinoids and Identification of Optimal Urinary Marker Metabolites.Motor vehicle collisions caused by the 'super-strength' synthetic cannabinoids, MAM-2201, 5F-PB-22, 5F-AB-PINACA, 5F-AMB and 5F-ADB in Japan experienced from 2012 to 2014.AB-CHMINACA, AB-PINACA, and FUBIMINA: Affinity and Potency of Novel Synthetic Cannabinoids in Producing Δ9-Tetrahydrocannabinol-Like Effects in MiceIdentification of AB-FUBINACA metabolites in authentic urine samples suitable as urinary markers of drug intake using liquid chromatography quadrupole tandem time of flight mass spectrometry.Metabolic profiling of new synthetic cannabinoids AMB and 5F-AMB by human hepatocyte and liver microsome incubations and high-resolution mass spectrometry.In vitro and in vivo human metabolism of a new synthetic cannabinoid NM-2201 (CBL-2201).4-Methoxy-α-PVP: in silico prediction, metabolic stability, and metabolite identification by human hepatocyte incubation and high-resolution mass spectrometry.In Vitro and In Vivo Human Metabolism of Synthetic Cannabinoids FDU-PB-22 and FUB-PB-22.The 2-alkyl-2H-indazole regioisomers of synthetic cannabinoids AB-CHMINACA, AB-FUBINACA, AB-PINACA, and 5F-AB-PINACA are possible manufacturing impurities with cannabimimetic activitiesStrategies to distinguish new synthetic cannabinoid FUBIMINA (BIM-2201) intake from its isomer THJ-2201: metabolism of FUBIMINA in human hepatocytes.Multiple stage MS in analysis of plasma, serum, urine and in vitro samples relevant to clinical and forensic toxicology.Advances in high-resolution MS and hepatocyte models solve a long-standing metabolism challenge: the loratadine story.High-resolution mass spectrometry in toxicology: current status and future perspectives.Detection of the recently emerged synthetic cannabinoid 5F-MDMB-PICA in 'legal high' products and human urine samples.New psychoactive substances: an overview on recent publications on their toxicodynamics and toxicokinetics.Fatal intoxication by 5F-ADB and diphenidine: Detection, quantification, and investigation of their main metabolic pathways in humans by LC/MS/MS and LC/Q-TOFMS.In vitro metabolism of the synthetic cannabinoids CUMYL-PINACA, 5F-CUMYL-PINACA, CUMYL-4CN-BINACA, 5F-CUMYL-P7AICA and CUMYL-4CN-B7AICA.Detection of metabolites of the new synthetic cannabinoid CUMYL-4CN-BINACA in authentic urine samples and human liver microsomes using high-resolution mass spectrometry.UPLC-HR-MS/MS-based determination study on the metabolism of four synthetic cannabinoids, ADB-FUBICA, AB-FUBICA, AB-BICA and ADB-BICA, by human liver microsomes.In Vitro Metabolite Profiling of ADB-FUBINACA, A New Synthetic Cannabinoid.Toxicokinetics of new psychoactive substances: plasma protein binding, metabolic stability, and human phase I metabolism of the synthetic cannabinoid WIN 55,212-2 studied using in vitro tools and LC-HR-MS/MS.Determination of urinary metabolites of XLR-11 by liquid chromatography-quadrupole time-of-flight mass spectrometry.The synthesis and characterization of the 'research chemical' N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-3-(4-fluorophenyl)-1H-pyrazole-5-carboxamide (3,5-AB-CHMFUPPYCA) and differentiation from its 5,3-regioisomer.In vitro metabolism of synthetic cannabinoid AM1220 by human liver microsomes and Cunninghamella elegans using liquid chromatography coupled with high resolution mass spectrometry.Atypical Pharmacodynamic Properties and Metabolic Profile of the Abused Synthetic Cannabinoid AB-PINACA: Potential Contribution to Pronounced Adverse Effects Relative to Δ-THC
P2860
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P2860
Pentylindole/Pentylindazole Synthetic Cannabinoids and Their 5-Fluoro Analogs Produce Different Primary Metabolites: Metabolite Profiling for AB-PINACA and 5F-AB-PINACA
description
2015 nî lūn-bûn
@nan
2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Pentylindole/Pentylindazole Sy ...... for AB-PINACA and 5F-AB-PINACA
@ast
Pentylindole/Pentylindazole Sy ...... for AB-PINACA and 5F-AB-PINACA
@en
Pentylindole/Pentylindazole Sy ...... for AB-PINACA and 5F-AB-PINACA
@nl
type
label
Pentylindole/Pentylindazole Sy ...... for AB-PINACA and 5F-AB-PINACA
@ast
Pentylindole/Pentylindazole Sy ...... for AB-PINACA and 5F-AB-PINACA
@en
Pentylindole/Pentylindazole Sy ...... for AB-PINACA and 5F-AB-PINACA
@nl
prefLabel
Pentylindole/Pentylindazole Sy ...... for AB-PINACA and 5F-AB-PINACA
@ast
Pentylindole/Pentylindazole Sy ...... for AB-PINACA and 5F-AB-PINACA
@en
Pentylindole/Pentylindazole Sy ...... for AB-PINACA and 5F-AB-PINACA
@nl
P2093
P2860
P1433
P1476
Pentylindole/Pentylindazole Sy ...... for AB-PINACA and 5F-AB-PINACA
@en
P2093
Ariane Wohlfarth
Karl B Scheidweiler
Marisol S Castaneto
Mingshe Zhu
Robert Kronstrand
Shaokun Pang
P2860
P2888
P304
P356
10.1208/S12248-015-9721-0
P407
P577
2015-02-28T00:00:00Z
P5875
P6179
1026853933