Ebola virus. Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment. - Wikidata - wikimedia - TriplyDB

Ebola virus. Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment.

Ebola virus. Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment.

http://www.wikidata.org/entity/Q34464824

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The cell surface environment for pathogen recognition and entry Tetrandrine, a Chinese plant-derived alkaloid, is a potential candidate for cancer chemotherapy Recent advances in biosynthesis of bioactive compounds in traditional Chinese medicinal plants The role of STIM and ORAI proteins in phagocytic immune cells The role of macropinocytosis in the propagation of protein aggregation associated with neurodegenerative diseases Ebolavirus Glycoprotein Directs Fusion through NPC1+ Endolysosomes Systems Biology-Based Investigation of Cellular Antiviral Drug Targets Identified by Gene-Trap Insertional Mutagenesis Regulation of lysosomal ion homeostasis by channels and transporters Fusion of Enveloped Viruses in Endosomes.Principles of Virus Uncoating: Cues and the Snooker Ball Structure of the voltage-gated two-pore channel TPC1 from Arabidopsis thaliana Structure, inhibition and regulation of two-pore channel TPC1 from Arabidopsis thaliana Evaluation of the Activity of Lamivudine and Zidovudine against Ebola Virus.Anti-Ebola therapies based on monoclonal antibodies: current state and challenges ahead.The phosphatidylinositol-3-phosphate 5-kinase inhibitor apilimod blocks filoviral entry and infection A screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity.Induction of Cell-Cell Fusion by Ebola Virus Glycoprotein: Low pH Is Not a Trigger Size Dependent Cellular Uptake of Rod-like Bionanoparticles with Different Aspect Ratios.High resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with Acidic Stores (lysosomes) in the heart Recombinant tandem of pore-domains in a Weakly Inward rectifying K+ channel 2 (TWIK2) forms active lysosomal channels.Naringenin Impairs Two-Pore Channel 2 Activity And Inhibits VEGF-Induced Angiogenesis.Molecular mechanisms of Ebola virus pathogenesis: focus on cell death.Function and dysfunction of two-pore channels.Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Endolysosomal Two-pore Channels Modulate Membrane Excitability and Stimulus-Secretion Coupling in Mouse Pancreatic β Cells.Two-Pore Channels: Lessons from Mutant Mouse Models Two-Pore Channels: Catalyzers of Endolysosomal Transport and Function.The human two-pore channel 1 is modulated by cytosolic and luminal calcium.Novel Arenavirus Entry Inhibitors Discovered by Using a Minigenome Rescue System for High-Throughput Drug Screening.Inhibition of Ebola and Marburg Virus Entry by G Protein-Coupled Receptor Antagonists The Glycoproteins of All Filovirus Species Use the Same Host Factors for Entry into Bat and Human Cells but Entry Efficiency Is Species Dependent.Large-Scale Screening and Identification of Novel Ebola Virus and Marburg Virus Entry Inhibitors New targets for controlling Ebola virus disease Intracellular sphingosine releases calcium from lysosomes.Modulation of Potassium Channels Inhibits Bunyavirus Infection.Direct Visualization of Ebola Virus Fusion Triggering in the Endocytic Pathway.TPC2 controls pigmentation by regulating melanosome pH and size Prophylactic Efficacy of Quercetin 3-β-O-d-Glucoside against Ebola Virus Infection.Ebola VP40 in Exosomes Can Cause Immune Cell Dysfunction.Selective inhibition of Ebola entry with selective estrogen receptor modulators by disrupting the endolysosomal calcium.Two-pore channels (TPCs): Novel voltage-gated ion channels with pleiotropic functions.

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Ebola virus. Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment.

http://www.wikidata.org/entity/Q34464824

description

2015 nî lūn-bûn

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2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2015 թվականի փետրվարին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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Ebola virus. Two-pore channels ...... targets for disease treatment.

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Ebola virus. Two-pore channels ...... targets for disease treatment.

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Ebola virus. Two-pore channels ...... targets for disease treatment.

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Ebola virus. Two-pore channels ...... targets for disease treatment.

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Ebola virus. Two-pore channels ...... targets for disease treatment.

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Ebola virus. Two-pore channels ...... targets for disease treatment.

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Andrey A Kolokoltsov

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Cheng-Chang Chen

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Christian Grimm

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Christian Wahl-Schott

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Martin Biel

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Michael W Tidwell

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Norbert Klugbauer

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Robert A Davey

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William E Bauta

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Yasuteru Sakurai

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P2860

Cellular entry of ebola virus involves uptake by a macropinocytosis-like mechanism and subsequent trafficking through early and late endosomes

A systematic screen of FDA-approved drugs for inhibitors of biological threat agents

T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus

mTOR regulates lysosomal ATP-sensitive two-pore Na(+) channels to adapt to metabolic state

NAADP mobilizes calcium from acidic organelles through two-pore channels

Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection

Ebola virus entry requires the cholesterol transporter Niemann-Pick C1

C-type lectins DC-SIGN and L-SIGN mediate cellular entry by Ebola virus in cis and in trans

Ebola haemorrhagic fever

Identification of a chemical probe for NAADP by virtual screening

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Ebola virus disease

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