IL-4 inhibits osteoclast formation through a direct action on osteoclast precursors via peroxisome proliferator-activated receptor gamma 1. - Wikidata - wikimedia - TriplyDB

IL-4 inhibits osteoclast formation through a direct action on osteoclast precursors via peroxisome proliferator-activated receptor gamma 1.

IL-4 inhibits osteoclast formation through a direct action on osteoclast precursors via peroxisome proliferator-activated receptor gamma 1.

http://www.wikidata.org/entity/Q34465312

about

Osteoimmunology: interactions of the bone and immune system Vitamin D and bone health: potential mechanisms.PPARgamma mediates NSAIDs-induced upregulation of TFF2 expression in gastric epithelial cells Disruption of Fnip1 reveals a metabolic checkpoint controlling B lymphocyte development Interleukin-4 inhibition of interleukin-1-induced expression of matrix metalloproteinase-3 (MMP-3) is independent of lipoxygenase and PPARgamma activation in human gingival fibroblasts.A novel osteoclast precursor cell line, 4B12, recapitulates the features of primary osteoclast differentiation and function: enhanced transfection efficiency before and after differentiation.Deletion of the alpha-arrestin protein Txnip in mice promotes adiposity and adipogenesis while preserving insulin sensitivity.The peroxisome proliferator-activated receptor (PPAR) alpha agonist fenofibrate maintains bone mass, while the PPAR gamma agonist pioglitazone exaggerates bone loss, in ovariectomized rats Essential role for hematopoietic prostaglandin D2 synthase in the control of delayed type hypersensitivity.Role of RANKL and RANK in bone loss and arthritis.PPARγ: a circadian transcription factor in adipogenesis and osteogenesis.Electrophilic PPARγ Ligands Attenuate IL-1β and Silica-Induced Inflammatory Mediator Production in Human Lung Fibroblasts via a PPARγ-Independent Mechanism.Anti-inflammatory effects of thiazolidinediones in human airway smooth muscle cells.Resolving the Two "Bony" Faces of PPAR-gamma.Impact of targeted PPARγ disruption on bone remodeling.Adipocyte lineage cells contribute to the skin stem cell niche to drive hair cycling.Modulation of osteoclastogenesis induced by nucleoside reverse transcriptase inhibitors.'Old drugs for new applications': can orthopedic research benefit from this strategy?Immunoregulation of bone remodelling Rosiglitazone induces decreases in bone mass and strength that are reminiscent of aged bone The role of the immune system in the pathophysiology of osteoporosis.Peroxisome proliferator-activated receptor gamma is a target of progesterone regulation in the preovulatory follicles and controls ovulation in mice.Intradermal adipocytes mediate fibroblast recruitment during skin wound healing.Peroxisome proliferator-activated receptor-gamma ligands as bone turnover modulators.New insights into osteoporosis: the bone-fat connection Peroxisome proliferator-activated receptors (PPARs) in the control of bone metabolism.Osteoimmunology: cytokines and the skeletal system.Impact of conjugated linoleic acid on bone physiology: proposed mechanism involving inhibition of adipogenesis.Complex regulation of tartrate-resistant acid phosphatase (TRAP) expression by interleukin 4 (IL-4): IL-4 indirectly suppresses receptor activator of NF-kappaB ligand (RANKL)-mediated TRAP expression but modestly induces its expression directly Proteomic approaches to study osteoclast biology.Dendritic cells enhance UHMWPE wear particle-induced osteoclast differentiation of macrophages.A review on interleukins: The key manipulators in rheumatoid arthritis.Normal human primary CD4+ T lymphocytes synthesize and release functional osteoprotegerin in vitro.Epidermal peroxisome proliferator-activated receptor gamma as a target for ultraviolet B radiation.The effect of local IL-4 delivery or CCL2 blockade on implant fixation and bone structural properties in a mouse model of wear particle induced osteolysis.Establishment of NF-κB sensing and interleukin-4 secreting mesenchymal stromal cells as an "on-demand" drug delivery system to modulate inflammation.Inflammatory cells and bone loss in rheumatoid arthritis.Stimulation of fat storage by prostacyclin and selective agonists of prostanoid IP receptor during the maturation phase of cultured adipocytes.Reciprocal effects of Interferon-γ and IL-4 on differentiation to osteoclast-like cells by RANKL or LPS.Peroxisome proliferator-activated receptor gamma agonist ligands stimulate a Th2 cytokine response and prevent acute colitis.

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IL-4 inhibits osteoclast formation through a direct action on osteoclast precursors via peroxisome proliferator-activated receptor gamma 1.

http://www.wikidata.org/entity/Q34465312

description

2001 nî lūn-bûn

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2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2001 թվականի փետրվարին հրատարակված գիտական հոդված

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2001年の論文

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IL-4 inhibits osteoclast forma ...... or-activated receptor gamma 1.

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IL-4 inhibits osteoclast forma ...... or-activated receptor gamma 1.

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IL-4 inhibits osteoclast forma ...... or-activated receptor gamma 1.

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type

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IL-4 inhibits osteoclast forma ...... or-activated receptor gamma 1.

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IL-4 inhibits osteoclast forma ...... or-activated receptor gamma 1.

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IL-4 inhibits osteoclast forma ...... or-activated receptor gamma 1.

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prefLabel

IL-4 inhibits osteoclast forma ...... or-activated receptor gamma 1.

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IL-4 inhibits osteoclast forma ...... or-activated receptor gamma 1.

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IL-4 inhibits osteoclast forma ...... or-activated receptor gamma 1.

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Proceedings of the National Academy of Sciences of the United States of America

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IL-4 inhibits osteoclast forma ...... or-activated receptor gamma 1.

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A C Bendixen

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C D Funk

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J W Pike

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K M Dienger

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N K Shevde

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P2860

PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL

TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells

Specific inflammatory cytokines regulate the expression of human monocyte 15-lipoxygenase

Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families

An interleukin-4-induced transcription factor: IL-4 Stat

Peroxisome proliferator-activated receptors: structures and function

Disruption of 12/15-lipoxygenase expression in peritoneal macrophages. Enhanced utilization of the 5-lipoxygenase pathway and diminished oxidation of low density lipoprotein

Differential expression and activation of a family of murine peroxisome proliferator-activated receptors

Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

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10.1073/PNAS.041493198

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30157

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