Molecular basis of congenital insensitivity to pain with anhidrosis (CIPA): mutations and polymorphisms in TRKA (NTRK1) gene encoding the receptor tyrosine kinase for nerve growth factor.
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A gain-of-function mutation in TRPA1 causes familial episodic pain syndromeNeurotrophin-regulated signalling pathwaysUncoupling of molecular maturation from peripheral target innervation in nociceptors expressing a chimeric TrkA/TrkC receptorOral and craniofacial manifestations and two novel missense mutations of the NTRK1 gene identified in the patient with congenital insensitivity to pain with anhidrosisIn vivo regulation of NGF-mediated functions by Nedd4-2 ubiquitination of TrkASingle cycle structure-based humanization of an anti-nerve growth factor therapeutic antibodyWhole genome sequencing of one complex pedigree illustrates challenges with genomic medicineMechanisms of nerve growth factor signaling in bone nociceptors and in an animal model of inflammatory bone pain.A genetic basis for mechanosensory traits in humansGenes for hereditary sensory and autonomic neuropathies: a genotype-phenotype correlation.Pharmacogenetics of new analgesics.Heat avoidance is regulated by transient receptor potential (TRP) channels and a neuropeptide signaling pathway in Caenorhabditis elegans.Potential mechanisms for hypoalgesia induced by anti-nerve growth factor immunoglobulin are identified using autoimmune nerve growth factor deprivation.Novel and novel de novo mutations in NTRK1 associated with congenital insensitivity to pain with anhidrosis: a case report.Update Review and Clinical Presentation in Congenital Insensitivity to Pain and Anhidrosis.Identification of pyrazine-based TrkA inhibitors: design, synthesis, evaluation, and computational modeling studies.Frequency of mutations in the genes associated with hereditary sensory and autonomic neuropathy in a UK cohortGenetic mutations that prevent pain: implications for future pain medication.The CRISPR/Cas9 system for gene editing and its potential application in pain researchNeuropathic pain: a maladaptive response of the nervous system to damage.Nerve growth factor, pain, itch and inflammation: lessons from congenital insensitivity to pain with anhidrosis.Genetic variability of pain perception and treatment--clinical pharmacological implications.Neurotrophins in healthy and diseased skinNerve growth factor and the physiology of pain: lessons from congenital insensitivity to pain with anhidrosis.Nerve growth factor and Alzheimer's disease: new facts for an old hypothesis.Neurotrophins, endocannabinoids and thermo-transient receptor potential: a threesome in pain signalling.Neurobiology of pain, interoception and emotional response: lessons from nerve growth factor-dependent neurons.Neuronal CC chemokines: the distinct roles of CCL21 and CCL2 in neuropathic pain.Combining Human and Rodent Genetics to Identify New Analgesics.Exploring Missense Mutations in Tyrosine Kinases Implicated with Neurodegeneration.Mutations in TrkA Causing Congenital Insensitivity to Pain with Anhidrosis (CIPA) Induce Misfolding, Aggregation, and Mutation-dependent Neurodegeneration by Dysfunction of the Autophagic Flux.Pain research update from a genetic point of view.Neurotrophic tyrosine kinase receptor 1 is a direct transcriptional and epigenetic target of IL-13 involved in allergic inflammation.Molecular Mechanisms That Contribute to Bone Marrow PainIn vivo confocal microscopy of hereditary sensory and autonomic neuropathy.A case of congenital insensitivity to pain with anhidrosis.Atypical hereditary sensory and autonomic neuropathy type IV with neither mental retardation nor pain insensitivity.Phenotypic heterogeneity of intellectual disability in patients with congenital insensitivity to pain with anhidrosis: A case report and literature review.Swedish Nerve Growth Factor Mutation (NGFR100W) Defines a Role for TrkA and p75NTR in Nociception.Exome sequencing identifies novel NTRK1 mutations in patients with HSAN-IV phenotype.
P2860
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P2860
Molecular basis of congenital insensitivity to pain with anhidrosis (CIPA): mutations and polymorphisms in TRKA (NTRK1) gene encoding the receptor tyrosine kinase for nerve growth factor.
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Molecular basis of congenital ...... inase for nerve growth factor.
@ast
Molecular basis of congenital ...... inase for nerve growth factor.
@en
Molecular basis of congenital insensitivity to pain with anhidrosis
@nl
type
label
Molecular basis of congenital ...... inase for nerve growth factor.
@ast
Molecular basis of congenital ...... inase for nerve growth factor.
@en
Molecular basis of congenital insensitivity to pain with anhidrosis
@nl
prefLabel
Molecular basis of congenital ...... inase for nerve growth factor.
@ast
Molecular basis of congenital ...... inase for nerve growth factor.
@en
Molecular basis of congenital insensitivity to pain with anhidrosis
@nl
P356
P1433
P1476
Molecular basis of congenital ...... inase for nerve growth factor.
@en
P2093
P304
P356
10.1002/HUMU.1224
P577
2001-12-01T00:00:00Z