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Nitric oxide-induced cellular stress and p53 activation in chronic inflammation

Nitric oxide-induced cellular stress and p53 activation in chronic inflammation

http://www.wikidata.org/entity/Q34466925

about

Threshold effects of nitric oxide-induced toxicity and cellular responses in wild-type and p53-null human lymphoblastoid cells Nitrosative stress induces DNA strand breaks but not caspase mediated apoptosis in a lung cancer cell line Mechanisms of Photoaging and Cutaneous Photocarcinogenesis, and Photoprotective Strategies with Phytochemicals Gene expression profiles of NO- and HNO-donor treated breast cancer cells: insights into tumor response and resistance pathways Overexpression of human kynurenine-3-monooxygenase protects against 3-hydroxykynurenine-mediated apoptosis through bidirectional nonlinear feedback Caught in the cross fire: p53 in inflammation.Chemoprevention for colon cancer: new opportunities, fact or fiction?Immature myeloid cells directly contribute to skin tumor development by recruiting IL-17-producing CD4+ T cells Computational insights on the competing effects of nitric oxide in regulating apoptosis noxin, a novel stress-induced gene involved in cell cycle and apoptosis Repurposing the anti-malarial drug, quinacrine: new anti-colitis properties Signaling and stress: The redox landscape in NOS2 biology Nitric oxide is a key component in inflammation-accelerated tumorigenesis.p53 immunohistochemical expression in Barrett's esophagus before and after endoscopic ablation by argon plasma coagulation.Stress-specific response of the p53-Mdm2 feedback loop Chronic inflammation and cytokines in the tumor microenvironment.Clinical outcomes and correlates of TP53 mutations and cancer.Atm-deficient mice exhibit increased sensitivity to dextran sulfate sodium-induced colitis characterized by elevated DNA damage and persistent immune activation.American ginseng suppresses colitis through p53-mediated apoptosis of inflammatory cells.p53 mutation, deprivation and poor prognosis in primary breast cancer Resveratrol suppresses colitis and colon cancer associated with colitis.Diet, physical activity, and body size associations with rectal tumor mutations and epigenetic changes Split T cell tolerance against a self/tumor antigen: spontaneous CD4+ but not CD8+ T cell responses against p53 in cancer patients and healthy donors.Cancer gene discovery in hepatocellular carcinoma Alcohol consumption and rectal tumor mutations and epigenetic changes.Nitric oxide: perspectives and emerging studies of a well known cytotoxin Nitric oxide: NO apoptosis or turning it ON?The adaptive imbalance in base excision-repair enzymes generates microsatellite instability in chronic inflammation.Curcumin Inhibits STAT3 Signaling in the Colon of Dextran Sulfate Sodium-treated Mice.p73, the "assistant" guardian of the genome?Polyphenols and the modulation of gene expression pathways: can we eat our way out of the danger of chronic disease?Macrophages, nitric oxide and microRNAs are associated with DNA damage response pathway and senescence in inflammatory bowel disease Phosphorylated TP63 induces transcription of RPN13, leading to NOS2 protein degradation Colitis and colorectal cancer.The p53 tumor suppressor network is a key responder to microenvironmental components of chronic inflammatory stress.TAp73 induction by nitric oxide: regulation by checkpoint kinase 1 (CHK1) and protection against apoptosis.Hypoxic inducible factor 1alpha, extracellular signal-regulated kinase, and p53 are regulated by distinct threshold concentrations of nitric oxide.PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and mice.Chemistry meets biology in colitis-associated carcinogenesis Elevated interferon gamma signaling contributes to impaired regeneration in the aged liver.

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Nitric oxide-induced cellular stress and p53 activation in chronic inflammation

http://www.wikidata.org/entity/Q34466925

description

2002 nî lūn-bûn

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2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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Nitric oxide-induced cellular stress and p53 activation in chronic inflammation

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Nitric oxide-induced cellular stress and p53 activation in chronic inflammation

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Nitric oxide-induced cellular stress and p53 activation in chronic inflammation

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Nitric oxide-induced cellular stress and p53 activation in chronic inflammation

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Nitric oxide-induced cellular stress and p53 activation in chronic inflammation

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Nitric oxide-induced cellular stress and p53 activation in chronic inflammation

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Proceedings of the National Academy of Sciences of the United States of America

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Nitric oxide-induced cellular stress and p53 activation in chronic inflammation

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Chamelli Jhappan

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Curtis C Harris

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David A Wink

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Ettore Appella

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Irit Zurer

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Katrina M Miranda

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Lorne J Hofseth

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Martha M Quezado

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Michael G Espey

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Peijun He

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P2860

GADD45 induction of a G2/M cell cycle checkpoint

A proinflammatory cytokine inhibits p53 tumor suppressor activity

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

Mdm2 promotes the rapid degradation of p53

Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53

A genetic model for colorectal tumorigenesis

Regulation of p53 stability by Mdm2

Surfing the p53 network

Lessons from hereditary colorectal cancer

Increased p53 mutation load in nontumorous human liver of wilson disease and hemochromatosis: oxyradical overload diseases

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