Determinants of translation elongation speed and ribosomal profiling biases in mouse embryonic stem cells.
about
Ribosome profiling: a Hi-Def monitor for protein synthesis at the genome-wide scaleMultiple roles of the coding sequence 5' end in gene expression regulationSelection for reduced translation costs at the intronic 5' end in fungiHigh-Resolution Analysis of Coronavirus Gene Expression by RNA Sequencing and Ribosome Profiling.Protein functional features are reflected in the patterns of mRNA translation speed.Detecting translational regulation by change point analysis of ribosome profiling data setsMean of the typical decoding rates: a new translation efficiency index based on the analysis of ribosome profiling data.Entrainment to periodic initiation and transition rates in a computational model for gene translationDistinct stages of the translation elongation cycle revealed by sequencing ribosome-protected mRNA fragments.Accurate Recovery of Ribosome Positions Reveals Slow Translation of Wobble-Pairing Codons in YeastA critical analysis of codon optimization in human therapeutics.The effect of tRNA levels on decoding times of mRNA codons.Temporally and spatially restricted gene expression profilingInsights into the mechanisms of eukaryotic translation gained with ribosome profilingModified ribosome profiling reveals high abundance of ribosome protected mRNA fragments derived from 3' untranslated regions.Quantifying the effect of ribosomal density on mRNA stabilityIncreased functional protein expression using nucleotide sequence features enriched in highly expressed genes in zebrafish.Properties and determinants of codon decoding time distributions.Unbiased Quantitative Models of Protein Translation Derived from Ribosome Profiling Data.Pateamine A-sensitive ribosome profiling reveals the scope of translation in mouse embryonic stem cellsRole of mRNA structure in the control of protein foldingRibosome profiling reveals the rhythmic liver translatome and circadian clock regulation by upstream open reading framesRiboAbacus: a model trained on polyribosome images predicts ribosome density and translational efficiency from mammalian transcriptomes.Complementary Post Transcriptional Regulatory Information is Detected by PUNCH-P and Ribosome Profiling.Integrated in vivo and in vitro nascent chain profiling reveals widespread translational pausing.Differences in codon bias and GC content contribute to the balanced expression of TLR7 and TLR9Estimation of ribosome profiling performance and reproducibility at various levels of resolution.Comparative ribosome profiling reveals extensive translational complexity in different Trypanosoma brucei life cycle stages.Translation elongation can control translation initiation on eukaryotic mRNAs.Challenges and obstacles related to solving the codon bias riddles.The translational machinery is an optimized molecular network that affects cellular homoeostasis and disease.Insights into RNA structure and function from genome-wide studies.Synonymous codons, ribosome speed, and eukaryotic gene expression regulation.Translatome profiling: methods for genome-scale analysis of mRNA translation.Computational analysis of nascent peptides that induce ribosome stalling and their proteomic distribution in Saccharomyces cerevisiae.Conformational Dynamics of mRNA in Gene Expression as New Pharmaceutical Target.Comparative survey of the relative impact of mRNA features on local ribosome profiling read density.Ribosome flow model with positive feedback.A comparative genomics study on the effect of individual amino acids on ribosome stalling.Genetic Code Optimization for Cotranslational Protein Folding: Codon Directional Asymmetry Correlates with Antiparallel Betasheets, tRNA Synthetase Classes
P2860
Q26822785-43B645E4-FA28-44F1-81A9-D20A9BB52D73Q27008936-1A9402E2-3B69-478A-87EF-21BC2E2516A5Q27302027-42D97B2E-2550-42B3-91EA-19B46363663BQ30384940-70548EAD-5E3F-426D-B9A0-252358A7A038Q30657282-EC0CC545-CE6B-4B6D-956A-8C1F949A5C5DQ30844222-26AF1D97-3129-418C-BE59-39D740911D06Q30873166-8FC51693-EFDE-4A50-BB8E-84A43917334DQ33572739-A4CDA19C-C31A-4492-A144-69C9B5F60397Q33738456-C8397753-ADDB-45A4-90A4-37B5DD5B5C53Q33786227-F9D21CB3-AE81-470C-907C-D93FCCF12C11Q34042157-25464F62-F3F4-4CFB-AB3B-E3514EB29D3BQ34044490-F8F5A77C-8F23-483A-BCEE-E49FFF8B0299Q34049706-466BFE80-EB9C-45B6-AE3E-6D34A9169DE4Q34546772-DE37799C-5695-443E-9384-8346D1119CF1Q35097948-6D6939FB-C676-49DA-80DA-3336B62A4FD7Q35206433-B976B9AE-C040-4748-8EF0-A026359F02EFQ35476197-58106D69-4432-4F6B-9ABC-3EAD42722859Q35540577-13E91B36-2A28-47F0-BD03-93FCEB1C7028Q35746477-A34345A6-FB18-490C-9461-25C56DA8C34CQ35893454-4214C2D8-C9F8-44FA-8C9A-530FF4D94B56Q36088168-D490B2F1-39FA-4B1E-B457-8823827A766EQ36333702-4C58DA41-ED31-4B22-936D-5FF034667D74Q36370867-96204154-DABE-48C7-B486-97FB28327AC0Q36602379-5FBCA6D0-8D1F-415D-B064-B35F33D4CE0AQ36607387-61E3E07B-76C5-4FF2-8B3F-8514E91D1F1AQ36684831-49984551-1B96-46F5-9568-3BBFDC536734Q36887006-B5610D92-956C-4856-B737-DA052F0B2254Q37680364-8D9626B8-5465-473D-AD60-F9C87FF67EC0Q37708983-5A5A672B-2D11-4862-A36D-1B248F6DC91EQ38180772-F1FA971A-8F0E-4D17-A52F-F97A7573672FQ38180775-AE85F34C-9D98-4CB0-9559-D456D0C20C56Q38211391-91625409-761E-4EDD-BA78-E8DA1A0B5899Q38231225-4A6F41BD-FA35-404A-B222-12D5F8A4E702Q38266157-AEE9AF24-CE0C-43FF-9BAF-A647B02B60B2Q38863924-80EF391B-4128-4F64-BC48-A47F609A245AQ39312942-01D762C4-B627-4FB3-9BF1-3EC9264C9051Q39326637-006D585A-5F88-4333-B8BB-62507C84C429Q40224935-5E86461A-5293-432A-8206-8672046BC0D3Q40451655-2CBB810E-F551-4D37-8754-57C3EBB6B69FQ41472888-D357613B-1CA5-4AE1-9A35-9E6AEBC460FF
P2860
Determinants of translation elongation speed and ribosomal profiling biases in mouse embryonic stem cells.
description
2012 nî lūn-bûn
@nan
2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Determinants of translation el ...... in mouse embryonic stem cells.
@ast
Determinants of translation el ...... in mouse embryonic stem cells.
@en
Determinants of translation el ...... in mouse embryonic stem cells.
@nl
type
label
Determinants of translation el ...... in mouse embryonic stem cells.
@ast
Determinants of translation el ...... in mouse embryonic stem cells.
@en
Determinants of translation el ...... in mouse embryonic stem cells.
@nl
prefLabel
Determinants of translation el ...... in mouse embryonic stem cells.
@ast
Determinants of translation el ...... in mouse embryonic stem cells.
@en
Determinants of translation el ...... in mouse embryonic stem cells.
@nl
P2860
P1476
Determinants of translation el ...... in mouse embryonic stem cells.
@en
P2093
Alexandra Dana
P2860
P304
P356
10.1371/JOURNAL.PCBI.1002755
P50
P577
2012-11-01T00:00:00Z