Evidence that exposure of the telomere 3' overhang sequence induces senescence - Wikidata - wikimedia - TriplyDB

Evidence that exposure of the telomere 3' overhang sequence induces senescence

Evidence that exposure of the telomere 3' overhang sequence induces senescence

http://www.wikidata.org/entity/Q34470102

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POT1 and TRF2 cooperate to maintain telomeric integrity Overexpression of Bcl-2 is associated with apoptotic resistance to the G-quadruplex ligand 12459 but is not sufficient to confer resistance to long-term senescence Telomestatin-induced telomere uncapping is modulated by POT1 through G-overhang extension in HT1080 human tumor cells.The oxidative stress adaptor p66Shc is required for permanent embryo arrest in vitro.Endothelial progenitor cells dysfunction and senescence: contribution to oxidative stress.Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA.Telomere homolog oligonucleotides induce apoptosis in malignant but not in normal lymphoid cells: mechanism and therapeutic potential Metabolism, genomics, and DNA repair in the mouse aging liver.Radiosensitization of mammary carcinoma cells by telomere homolog oligonucleotide pretreatment.T-oligos inhibit growth and induce apoptosis in human ovarian cancer cells A role for WRN in telomere-based DNA damage responses.Molecular mechanisms and in vivo mouse models of skin aging associated with dermal matrix alterations.Telomerase as a novel and potentially selective target for cancer chemotherapy.Mechanism of T-oligo-induced cell cycle arrest in Mia-PaCa pancreatic cancer cells.Telomeric DNA induces apoptosis and senescence of human breast carcinoma cells.Telomere Fragment Induced Amnion Cell Senescence: A Contributor to Parturition?DNA damage, cellular senescence and organismal ageing: causal or correlative?Topical thymidine dinucleotide treatment reduces development of ultraviolet-induced basal cell carcinoma in Ptch-1+/- mice Permanent embryo arrest: molecular and cellular concepts.Telomere homolog oligonucleotides and the skin: current status and future perspectives.Photoageing: mechanism, prevention and therapy.Nontelomeric TRF2-REST interaction modulates neuronal gene silencing and fate of tumor and stem cells.Telomere targeting with a novel G-quadruplex-interactive ligand BRACO-19 induces T-loop disassembly and telomerase displacement in human glioblastoma cells.Photoprotection in human skin--a multifaceted SOS response.Mechanism of DNA damage responses induced by exposure to an oligonucleotide homologous to the telomere overhang in melanoma.Topical DNA oligonucleotide therapy reduces UV-induced mutations and photocarcinogenesis in hairless mice.Elevated miR-34c-5p mediates dermal fibroblast senescence by ultraviolet irradiation.Enhanced cytotoxicity from deoxyguanosine-enriched T-oligo in prostate cancer cells.Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer MLL associates with telomeres and regulates telomeric repeat-containing RNA transcription Senescence, apoptosis, and stem cell biology: the rationale for an expanded view of intracrine action Molecular distinctions between stasis and telomere attrition senescence barriers shown by long-term culture of normal human mammary epithelial cells.TERRA biogenesis, turnover and implications for function.Treating Cancer by Targeting Telomeres and Telomerase.Star-shaped tetraspermine enhances cellular uptake and cytotoxicity of T-oligo in prostate cancer cells.hnRNP C1/C2 and Pur-beta proteins mediate induction of senescence by oligonucleotides homologous to the telomere overhang.T-oligo treatment decreases constitutive and UVB-induced COX-2 levels through p53- and NFkappaB-dependent repression of the COX-2 promoter.Telomeric DNA induces p53-dependent reactive oxygen species and protects against oxidative damage.Novel delivery system for T-oligo using a nanocomplex formed with an alpha helical peptide for melanoma therapy.Non-small cell lung cancer is susceptible to induction of DNA damage responses and inhibition of angiogenesis by telomere overhang oligonucleotides.

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P2860

Evidence that exposure of the telomere 3' overhang sequence induces senescence

http://www.wikidata.org/entity/Q34470102

description

2003 nî lūn-bûn

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2003 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի հունվարին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

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2003年论文

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name

Evidence that exposure of the telomere 3' overhang sequence induces senescence

@ast

Evidence that exposure of the telomere 3' overhang sequence induces senescence

@en

Evidence that exposure of the telomere 3' overhang sequence induces senescence

@nl

type

label

Evidence that exposure of the telomere 3' overhang sequence induces senescence

@ast

Evidence that exposure of the telomere 3' overhang sequence induces senescence

@en

Evidence that exposure of the telomere 3' overhang sequence induces senescence

@nl

prefLabel

Evidence that exposure of the telomere 3' overhang sequence induces senescence

@ast

Evidence that exposure of the telomere 3' overhang sequence induces senescence

@en

Evidence that exposure of the telomere 3' overhang sequence induces senescence

@nl

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Evidence that exposure of the telomere 3' overhang sequence induces senescence

@en

P2093

Guang-Zhi Li

http://www.w3.org/2001/XMLSchema#string

Mark S Eller

http://www.w3.org/2001/XMLSchema#string

Reza Firoozabadi

http://www.w3.org/2001/XMLSchema#string

P2860

Mammalian telomeres end in a large duplex loop

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

Extension of the replicative life span of human diploid fibroblasts by inhibition of the p33ING1 candidate tumor suppressor

TRF2 Protects Human Telomeres from End-to-End Fusions

How to activate p53

Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence

The candidate tumour suppressor p33ING1 cooperates with p53 in cell growth control

Senescence Induced by Altered Telomere State, Not Telomere Loss

p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

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527-531

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Barbara Gilchrest

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