NPI-2358 is a tubulin-depolymerizing agent: in-vitro evidence for activity as a tumor vascular-disrupting agent.
about
A novel vascular disrupting agent plinabulin triggers JNK-mediated apoptosis and inhibits angiogenesis in multiple myeloma cellsTubulin-interactive natural products as anticancer agentsMarine Natural Products as Models to Circumvent Multidrug ResistanceMicrowave-Assisted Synthesis of Bioactive Six-Membered Heterocycles and Their Fused AnaloguesRational and combinatorial tailoring of bioactive cyclic dipeptidesTubulin-destabilizing agent BPR0L075 induces vascular-disruption in human breast cancer mammary fat pad xenograftsKPU-300, a Novel Benzophenone-Diketopiperazine-Type Anti-Microtubule Agent with a 2-Pyridyl Structure, Is a Potent Radiosensitizer That Synchronizes the Cell Cycle in Early M PhaseA new diketopiperazine derivative from a deep sea-derived Streptomyces sp. SCSIO 04496.Efficient construction of diketopiperazine macroarrays through a cyclative-cleavage strategy and their evaluation as luminescence inhibitors in the bacterial symbiont Vibrio fischeriMarine antitumor drugs: status, shortfalls and strategies.Cyclic dipeptides from rhabditid entomopathogenic nematode-associated Bacillus cereus have antimicrobial activities.A perspective on vascular disrupting agents that interact with tubulin: preclinical tumor imaging and biological assessmentRole of the cytoskeleton in formation and maintenance of angiogenic sproutsDiversity-oriented synthesis as a tool for chemical genetics.Can Some Marine-Derived Fungal Metabolites Become Actual Anticancer Agents?Anticancer potential of pyrrole (1, 2, a) pyrazine 1, 4, dione, hexahydro 3-(2-methyl propyl) (PPDHMP) extracted from a new marine bacterium, Staphylococcus sp. strain MB30.Synthesis of deuterium-enriched and fluorine-substituted plinabulin derivatives and evaluation of their antitumor activities.Strategies for the Optimization of Natural Leads to Anticancer Drugs or Drug Candidates.Vascular effects of plinabulin (NPI-2358) and the influence on tumour response when given alone or combined with radiation.Development of new cancer therapeutic agents targeting mitosis.Marine-derived angiogenesis inhibitors for cancer therapy.Ferrocenyl 2,5-Piperazinediones as Tubulin-Binding Organometallic ABCB1 and ABCG2 Inhibitors Active against MDR Cells.Solid-phase and microwave-assisted syntheses of 2,5-diketopiperazines: small molecules with great potentialThe effect of beta-elemene on alpha-tubulin polymerization in human hepatoma HepG2 cells.Tumor vasculature as target for therapeutic intervention.Antiangiogenic agents in the management of non-small cell lung cancer: where do we stand now and where are we headed?Recent developments in asymmetric multicomponent reactions.Indole molecules as inhibitors of tubulin polymerization: potential new anticancer agents.Vascular-disrupting agents in oncology.Developments around the bioactive diketopiperazines: a patent review.Angiogenesis at the mold-host interface: a potential key to understanding and treating invasive aspergillosis.Isocyanide-based multicomponent reactions towards cyclic constrained peptidomimetics.Anticancer agent-based marine natural products and related compounds.Early investigational tubulin inhibitors as novel cancer therapeutics.Antimycobacterial activity of cyclic dipeptides isolated from Bacillus sp. N strain associated with entomopathogenic nematode.Activity and synergistic antimicrobial activity between diketopiperazines against bacteria in vitro.Studies on the secondary metabolites of a Pseudoalteromonas sp. isolated from sediments collected at the northeastern coast of Brazil.Suppressive effects of three diketopiperazines from marine-derived bacteria on TGFBIp-mediated septic responses in human endothelial cells and mice.Induction of systemic disease resistance in Nicotiana benthamiana by the cyclodipeptides cyclo (l-Pro-l-Pro) and cyclo (d-Pro-d-Pro).Antagonistic Properties of Some Halophilic Thermoactinomycetes Isolated from Superficial Sediment of a Solar Saltern and Production of Cyclic Antimicrobial Peptides by the Novel Isolate Paludifilum halophilum.
P2860
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P2860
NPI-2358 is a tubulin-depolymerizing agent: in-vitro evidence for activity as a tumor vascular-disrupting agent.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
NPI-2358 is a tubulin-depolyme ...... mor vascular-disrupting agent.
@ast
NPI-2358 is a tubulin-depolyme ...... mor vascular-disrupting agent.
@en
NPI-2358 is a tubulin-depolyme ...... mor vascular-disrupting agent.
@nl
type
label
NPI-2358 is a tubulin-depolyme ...... mor vascular-disrupting agent.
@ast
NPI-2358 is a tubulin-depolyme ...... mor vascular-disrupting agent.
@en
NPI-2358 is a tubulin-depolyme ...... mor vascular-disrupting agent.
@nl
prefLabel
NPI-2358 is a tubulin-depolyme ...... mor vascular-disrupting agent.
@ast
NPI-2358 is a tubulin-depolyme ...... mor vascular-disrupting agent.
@en
NPI-2358 is a tubulin-depolyme ...... mor vascular-disrupting agent.
@nl
P2093
P1433
P1476
NPI-2358 is a tubulin-depolyme ...... mor vascular-disrupting agent.
@en
P2093
Benjamin Nicholson
Brian R Miller
G Kenneth Lloyd
Michael A Palladino
Saskia T C Neuteboom
Yoshiaki Kiso
Yoshio Hayashi
P356
10.1097/01.CAD.0000182745.01612.8A
P577
2006-01-01T00:00:00Z