Cyclin D1b variant influences prostate cancer growth through aberrant androgen receptor regulation
about
The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic inventionSplicing Regulation: A Molecular Device to Enhance Cancer Cell AdaptationTargeting cyclin-dependent kinases in human cancers: from small molecules to Peptide inhibitorsMechanisms and consequences of alternative polyadenylationRole of Nuclear Receptors in Central Nervous System Development and Associated DiseasesCyclin D as a therapeutic target in cancerAlternative pre-mRNA splicing regulation in cancer: pathways and programs unhingedA multiscale, mechanism-driven, dynamic model for the effects of 5α-reductase inhibition on prostate maintenanceCell-cycle-dependent regulation of androgen receptor functionRSK in tumorigenesis: connections to steroid signaling.Progesterone receptors act as sensors for mitogenic protein kinases in breast cancer models.Repressive effects of resveratrol on androgen receptor transcriptional activity.Analysis of the molecular networks in androgen dependent and independent prostate cancer revealed fragile and robust subsystems.Cyclin D1 splice variants: polymorphism, risk, and isoform-specific regulation in prostate cancer.Identification of ASF/SF2 as a critical, allele-specific effector of the cyclin D1b oncogene.Cyclin D1 regulates hepatic estrogen and androgen metabolism.Cyclin D1b overexpression inhibits cell proliferation and induces cell apoptosis in cervical cancer cells in vitro and in vivo.Elevated SRPK1 lessens apoptosis in breast cancer cells through RBM4-regulated splicing events.Cyclin D1 is a selective modifier of androgen-dependent signaling and androgen receptor function.Cyclin D1b protein expression in breast cancer is independent of cyclin D1a and associated with poor disease outcomeRegulation of chemoresistance via alternative messenger RNA splicingPoint mutations and genomic deletions in CCND1 create stable truncated cyclin D1 mRNAs that are associated with increased proliferation rate and shorter survivalInfluence of CCND1 G870A polymorphism on the risk of HBV-related HCC and cyclin D1 splicing variant expression in Chinese population.Dual roles of PARP-1 promote cancer growth and progression.Convergence of oncogenic and hormone receptor pathways promotes metastatic phenotypes.The cyclin D1b splice variant: an old oncogene learns new tricks.Alteration of cyclin D1 transcript elongation by a mutated transcription factor up-regulates the oncogenic D1b splice isoform in cancerIntegration of progesterone receptor action with rapid signaling events in breast cancer models.Cyclins, cyclin dependent kinases, and regulation of steroid receptor action.AR, the cell cycle, and prostate cancer.Enhanced skin carcinogenesis and lack of thymus hyperplasia in transgenic mice expressing human cyclin D1b (CCND1b)Aberrant splice variants of HAS1 (Hyaluronan Synthase 1) multimerize with and modulate normally spliced HAS1 protein: a potential mechanism promoting human cancerIntegrated actions of progesterone receptor and cell cycle machinery regulate breast cancer cell proliferation.Akt-dependent activation of Erk by cyclin D1b contributes to cell invasiveness and tumorigenicityCyclin D1 in the Liver: Role of Noncanonical Signaling in Liver Steatosis and Hormone RegulationAndrogen receptor-dependent and -independent mechanisms driving prostate cancer progression: Opportunities for therapeutic targeting from multiple angles.The AR dependent cell cycle: mechanisms and cancer relevance.Androgen receptor co-activators in the regulation of cellular events in prostate cancer.RNA splicing: a new player in the DNA damage responseAR function in promoting metastatic prostate cancer
P2860
Q21245733-4DD7E168-65A6-4D8F-ACEA-BB61A59C6EECQ26798148-8650F2F5-2B21-4E2B-A870-059F45971201Q26827580-800D945D-5675-417C-8E50-BD8289316257Q26852702-D7C6EE7C-B61E-462F-A2E0-01F698610B37Q27025212-F824060B-F190-4643-BBF7-BD3BF9292ABDQ28242623-06EDDEB6-7582-43FC-BF64-53066B398FEAQ28297381-CB0D5984-A901-417E-B0E9-2FEBB920CE87Q28483635-6A1A08EC-5E24-45DB-9DA6-9F581435423CQ30300725-8F18C342-8FB9-40FA-98FA-1748553E7F91Q30433106-2D73BA86-791E-4573-8513-A6CB5DA0D510Q33428469-4CF586D3-FA4C-44E3-B116-9B79436F9E00Q33509527-3C27EF76-0476-4389-A1AA-3F9B0517C729Q33529070-67B2E587-C68D-4987-A03B-30D29B7A7515Q33768593-E4BC3EF2-E9AD-4CCE-9113-F74BDFB14AD5Q33865182-91B1DD47-0594-4394-850E-2CAECFF848D7Q34008011-4BB6E409-9A33-49A5-9F80-033D0BD12950Q34029095-31479E4F-9F7B-457D-B4D6-5A69BE4788E3Q34240895-CA6D5558-C79B-4A75-84A1-952713ED865BQ34624275-089E055E-47F1-4AC9-A932-E4884F1C68DDQ34775678-C4C6E4CB-14E0-4428-B046-65C43606852AQ35822883-C3AA0E4F-B7DF-407E-B5B1-8EF971737239Q35828800-BCF21020-F682-464C-B1C5-8EEF30F9AC65Q36278139-E5B8834E-42E5-4056-B192-7D78D0EF8E41Q36460391-BCB5FD57-184D-43FD-AD81-B06C7C9A4579Q36497254-7B0AAF30-51CB-4F80-8C5A-802A8DAFAABDQ36545151-67AC37AC-D6A7-43DD-ABE8-DC06BB503D1DQ36579430-1277243F-6AE4-4DCA-9C27-C6EA75E23967Q36580735-9AA17191-B079-4CFB-9605-60BE3F0BFDEFQ36701285-CD814B20-A583-4367-A087-B21EAE1F1D74Q37095260-0A3133A9-C558-4A3B-8CAE-EDA0C54839D5Q37251029-30AF26A2-B86C-4BB8-8838-7DF9329A903EQ37253985-13D66DA5-13BD-4B0F-AE80-8DBEC5B1F81EQ37360938-2DF8DAAE-4101-424F-A401-92C465654928Q37582078-74A60FBA-4859-4FA5-BB8D-76C9377DF2BBQ37698862-D1B52464-44BC-4935-9D45-C4B90ED573D6Q37709535-6C51ECD3-07A3-4656-8AE9-77DBBF744170Q37904028-666BD14A-43C2-4992-B237-6982EF5685E4Q37959244-A77951F4-11C8-4A67-B09F-809D44E0D30EQ38155497-6EB8AC1F-F5A6-458B-8E51-738D54E022F7Q38178555-99465617-2F81-4FE3-B85D-65D46F876F6C
P2860
Cyclin D1b variant influences prostate cancer growth through aberrant androgen receptor regulation
description
2006 nî lūn-bûn
@nan
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Cyclin D1b variant influences ...... t androgen receptor regulation
@ast
Cyclin D1b variant influences ...... t androgen receptor regulation
@en
Cyclin D1b variant influences ...... t androgen receptor regulation
@nl
type
label
Cyclin D1b variant influences ...... t androgen receptor regulation
@ast
Cyclin D1b variant influences ...... t androgen receptor regulation
@en
Cyclin D1b variant influences ...... t androgen receptor regulation
@nl
prefLabel
Cyclin D1b variant influences ...... t androgen receptor regulation
@ast
Cyclin D1b variant influences ...... t androgen receptor regulation
@en
Cyclin D1b variant influences ...... t androgen receptor regulation
@nl
P2093
P2860
P50
P356
P1476
Cyclin D1b variant influences ...... t androgen receptor regulation
@en
P2093
Cecilia M Fenoglio-Preiser
Christin E Petre
Erik S Knudsen
Jiemin Wong
Lisa M Morey
Monica P Revelo
P2860
P304
P356
10.1073/PNAS.0506281103
P407
P577
2006-02-06T00:00:00Z