Stereochemical aspects of itraconazole metabolism in vitro and in vivo.
about
Stereospecific metabolism of itraconazole by CYP3A4: dioxolane ring scission of azole antifungalsSubstrate Hunting for the Myxobacterial CYP260A1 Revealed New 1α-Hydroxylated Products from C-19 Steroids.Contribution of itraconazole metabolites to inhibition of CYP3A4 in vivo.Effect of CYP3A5 expression on the inhibition of CYP3A-catalyzed drug metabolism: impact on modeling CYP3A-mediated drug-drug interactions.Role of biotransformation studies in minimizing metabolism-related liabilities in drug discovery.Triazole antifungal agents drug-drug interactions involving hepatic cytochrome P450.Itraconazole: an update on pharmacology and clinical use for treatment of invasive and allergic fungal infections.Impact of Absolute Stereochemistry on the Antiangiogenic and Antifungal Activities of ItraconazoleType II ligands as chemical auxiliaries to favor enzymatic transformations by P450 2E1.Synthesis and in vitro and in vivo antifungal activity of the hydroxy metabolites of saperconazole.Stereoselective determination of the epimer mixtures of itraconazole in human blood plasma using HPLC and fluorescence detection.Pharmacogenomics of triazole antifungal agents: implications for safety, tolerability and efficacy.Use of a semi-physiological pharmacokinetic model to investigate the influence of itraconazole on tacrolimus absorption, distribution and metabolism in mice.Stereoselective metabolism of fenoxaprop-ethyl and its chiral metabolite fenoxaprop in rabbits.Syndrome of inappropriate antidiuretic hormone secretion from concomitant use of itraconazole and vindesine.
P2860
Q35776638-822385A3-259C-4BB3-AA3C-8B2DB65ADD2FQ35811942-C74D0F3C-4568-44CB-AEFE-34AF32526C6FQ36369136-8C5A2161-35E0-4509-B516-BDBA1A02B02EQ37027004-8FD198FE-4D38-4A3D-9430-E8AAD47630D0Q37150879-47F5B48C-ABC0-4271-A5C7-42940B21DA30Q37945308-50255500-1F6E-4E0C-9DCE-6DCC5C69BCC4Q38103889-DA79E90A-9B1A-4BFE-BEA0-721ADB67B489Q38280950-4F6C284C-8019-40F9-BEF7-955F2B1B02CAQ39524782-96DA7FD4-FB2A-40BF-B7A1-5BC3467A0308Q43105019-6156646C-3195-49EF-83F4-F986D3956110Q46537918-49E001FD-6C3E-48C6-B2B2-FE4D40CBB5F4Q47664190-7B57E9F3-AEC6-4EEF-8B2B-CA4921E4687AQ48566470-450A9BF0-10C5-4835-8CD7-582435127DABQ48887266-F530EFEF-006E-421B-B4FC-D6C3CEE24AA0Q53123208-467367EF-5C92-4894-A333-0948F8C4FCFC
P2860
Stereochemical aspects of itraconazole metabolism in vitro and in vivo.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Stereochemical aspects of itraconazole metabolism in vitro and in vivo.
@ast
Stereochemical aspects of itraconazole metabolism in vitro and in vivo.
@en
Stereochemical aspects of itraconazole metabolism in vitro and in vivo.
@nl
type
label
Stereochemical aspects of itraconazole metabolism in vitro and in vivo.
@ast
Stereochemical aspects of itraconazole metabolism in vitro and in vivo.
@en
Stereochemical aspects of itraconazole metabolism in vitro and in vivo.
@nl
prefLabel
Stereochemical aspects of itraconazole metabolism in vitro and in vivo.
@ast
Stereochemical aspects of itraconazole metabolism in vitro and in vivo.
@en
Stereochemical aspects of itraconazole metabolism in vitro and in vivo.
@nl
P2093
P356
P1476
Stereochemical aspects of itraconazole metabolism in vitro and in vivo.
@en
P2093
Evan D Kharasch
Kenneth E Thummel
Kent L Kunze
Nina Isoherranen
Wendel L Nelson
P304
P356
10.1124/DMD.105.008508
P577
2006-01-13T00:00:00Z