The covalent binding of daunomycin and adriamycin to antibodies, with retention of both drug and antibody activities.
about
Cytotoxic analogs of luteinizing hormone-releasing hormone containing doxorubicin or 2-pyrrolinodoxorubicin, a derivative 500-1000 times more potentPhosphorylcholine-based stealthy nanocapsules enabling tumor microenvironment-responsive doxorubicin release for tumor suppression.Doxorubicin conjugates of monoclonal antibodies to hepatoma-associated antigens.Inhibition of human tumor growth in nude mice by a conjugate of doxorubicin with monoclonal antibodies to epidermal growth factor receptorCancer targeted therapeutics: From molecules to drug delivery vehicles.A chemical perspective on the anthracycline antitumor antibioticsN-Sulfonyl-β-lactam hapten as an effective labeling reagent for aldolase mAb.Effect of a conjugate of daunomycin and antibodies to rat alpha-fetoprotein on the growth of alpha-fetoprotein-producing tumor cells.A covalent linkage between daunorubicin and proteins that is stable in serum and reversible by lysosomal hydrolases, as required for a lysosomotropic drug-carrier conjugate: in vitro and in vivo studies.Chemotherapy by intravenous administration of conjugates of daunomycin with monoclonal and conventional anti-rat alpha-fetoprotein antibodies.Antibody-directed cytotoxic agents: use of monoclonal antibody to direct the action of toxin A chains to colorectal carcinoma cellsA sensitive multidimensional method for the detection, characterization, and quantification of trace free drug species in antibody-drug conjugate samples using mass spectral detectionDoxorubicin Conjugated to Immunomodulatory Anticancer Lactoferrin Displays Improved Cytotoxicity Overcoming Prostate Cancer Chemo resistance and Inhibits Tumour Development in TRAMP MiceA conjugate of an anti-midkine single-chain variable fragment to doxorubicin inhibits tumor growth.Analytical methods for physicochemical characterization of antibody drug conjugatesIn vitro activity of daunomycin-anti-alphafoetoprotein conjugate on mouse hepatoma cells.Chemotherapeutic efficacy of the protein-doxorubicin conjugates on multidrug resistant rat hepatoma cell line in vitro.Low density lipoprotein for delivery of a water-insoluble alkylating agent to malignant cells. In vitro and in vivo studies of a drug-lipoprotein complex.My life with affinityBiodistribution of neocarzinostatin conjugated to chimeric Fab fragments of the monoclonal antibody A7 in nude mice bearing human pancreatic cancer xenografts.Comparative pharmacokinetic properties of murine monoclonal antibody A7 modified with neocarzinostatin, dextran and polyethylene glycol.Decreased renal accumulation of biotinylated chimeric monoclonal antibody-neocarzinostatin conjugate after administration of avidin.
P2860
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P2860
The covalent binding of daunomycin and adriamycin to antibodies, with retention of both drug and antibody activities.
description
1975 nî lūn-bûn
@nan
1975 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1975 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1975年の論文
@ja
1975年学术文章
@wuu
1975年学术文章
@zh-cn
1975年学术文章
@zh-hans
1975年学术文章
@zh-my
1975年学术文章
@zh-sg
1975年學術文章
@yue
name
The covalent binding of daunom ...... drug and antibody activities.
@ast
The covalent binding of daunom ...... drug and antibody activities.
@en
The covalent binding of daunom ...... drug and antibody activities.
@nl
type
label
The covalent binding of daunom ...... drug and antibody activities.
@ast
The covalent binding of daunom ...... drug and antibody activities.
@en
The covalent binding of daunom ...... drug and antibody activities.
@nl
prefLabel
The covalent binding of daunom ...... drug and antibody activities.
@ast
The covalent binding of daunom ...... drug and antibody activities.
@en
The covalent binding of daunom ...... drug and antibody activities.
@nl
P2093
P1433
P1476
The covalent binding of daunom ...... drug and antibody activities.
@en
P2093
P304
P407
P577
1975-05-01T00:00:00Z