Rapid, Microwave-Assisted Organic Synthesis of Selective (V600E)BRAF Inhibitors for Preclinical Cancer Research.

Rapid, Microwave-Assisted Organic Synthesis of Selective (V600E)BRAF Inhibitors for Preclinical Cancer Research.

Item
http://www.wikidata.org/entity/Q34488278
Facile synthesis of SSR180575 and discovery of 7-chloro-N,N,5-trimethyl-4-oxo-3(6-[(18)F]fluoropyridin-2-yl)-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide, a potent pyridazinoindole ligand for PET imaging of TSPO in cancer.3'-Deoxy-3'-18F-fluorothymidine PET predicts response to (V600E)BRAF-targeted therapy in preclinical models of colorectal cancer.Preclinical imaging evaluation of novel TSPO-PET ligand 2-(5,7-Diethyl-2-(4-(2-[(18)F]fluoroethoxy)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)-N,N-diethylacetamide ([ (18)F]VUIIS1008) in glioma.3'-Deoxy-3'-[18F]-Fluorothymidine PET imaging reflects PI3K-mTOR-mediated pro-survival response to targeted therapy in colorectal cancer.Microwave-assisted, one-pot reaction of 7-azaindoles and aldehydes: a facile route to novel di-7-azaindolylmethanes.A peptide-based positron emission tomography probe for in vivo detection of caspase activity in apoptotic cells.Non-Invasive Glutamine PET Reflects Pharmacological Inhibition of BRAFV600E In Vivo.
P2860

Rapid, Microwave-Assisted Organic Synthesis of Selective (V600E)BRAF Inhibitors for Preclinical Cancer Research.

Item
http://www.wikidata.org/entity/Q34488278
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2012年の論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年论文
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name
Rapid, Microwave-Assisted Orga ...... r Preclinical Cancer Research.
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Rapid, Microwave-Assisted Orga ...... r Preclinical Cancer Research.
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Rapid, Microwave-Assisted Orga ...... r Preclinical Cancer Research.
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Rapid, Microwave-Assisted Orga ...... r Preclinical Cancer Research.
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Rapid, Microwave-Assisted Orga ...... r Preclinical Cancer Research.
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Rapid, Microwave-Assisted Orga ...... r Preclinical Cancer Research.
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Rapid, Microwave-Assisted Orga ...... r Preclinical Cancer Research.
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Rapid, Microwave-Assisted Orga ...... r Preclinical Cancer Research.
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Rapid, Microwave-Assisted Orga ...... r Preclinical Cancer Research.
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Rapid, Microwave-Assisted Orga ...... r Preclinical Cancer Research.
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10.1016/J.TETLET.2012.05.137
P433
P478
P50
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P932