Trk retrograde signaling requires persistent, Pincher-directed endosomes
about
Christianson syndrome protein NHE6 modulates TrkB endosomal signaling required for neuronal circuit developmentHeterogeneous intracellular trafficking dynamics of brain-derived neurotrophic factor complexes in the neuronal soma revealed by single quantum dot trackingDelivery of CSF-1R to the lumen of macropinosomes promotes its destruction in macrophages.Coronin-1 is a neurotrophin endosomal effector that is required for developmental competition for survival.Retrolinkin cooperates with endophilin A1 to mediate BDNF-TrkB early endocytic trafficking and signaling from early endosomesThe neurotrophin receptor signaling endosome: Where trafficking meets signaling.Structural insights into the activation mechanism of dynamin-like EHD ATPases.Endocytosis and endosomes at the crossroads of regulating trafficking of axon outgrowth-modifying receptors.Retrograde transport of TrkB-containing autophagosomes via the adaptor AP-2 mediates neuronal complexity and prevents neurodegenerationNGF causes TrkA to specifically attract microtubules to lipid rafts.Biochemical and biophysical investigation of the brain-derived neurotrophic factor mimetic 7,8-dihydroxyflavone in the binding and activation of the TrkB receptor.Differential regulation of transcription factors by location-specific EGF receptor signaling via a spatio-temporal interplay of ERK activation.RabGEF1/Rabex-5 Regulates TrkA-Mediated Neurite Outgrowth and NMDA-Induced Signaling Activation in NGF-Differentiated PC12 Cells.Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac deathβ-Amyloid (Aβ) oligomers impair brain-derived neurotrophic factor retrograde trafficking by down-regulating ubiquitin C-terminal hydrolase, UCH-L1.Effects of membrane trafficking on signaling by receptor tyrosine kinases.IL-1β impairs retrograde flow of BDNF signaling by attenuating endosome traffickingParacrine control of vascular innervation in health and disease.The role of rab proteins in neuronal cells and in the trafficking of neurotrophin receptors.Biogenesis and function of the NGF/TrkA signaling endosomeAttractive and repulsive factors act through multi-subunit receptor complexes to regulate nerve fiber growth.Membrane turnover and receptor trafficking in regenerating axons.Cellular and molecular mechanisms regulating neuronal growth by brain-derived neurotrophic factor.Recruitment of actin modifiers to TrkA endosomes governs retrograde NGF signaling and survival.Kalirin is required for BDNF-TrkB stimulated neurite outgrowth and branching.Phosphorylation of NTRK1 at Y674/Y675 induced by TP53-dependent repression of PTPN6 expression: a potential novel prognostic marker for breast cancer.Dysfunction of autophagy and endosomal-lysosomal pathways: Roles in pathogenesis of Down syndrome and Alzheimer's Disease.
P2860
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P2860
Trk retrograde signaling requires persistent, Pincher-directed endosomes
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Trk retrograde signaling requires persistent, Pincher-directed endosomes
@ast
Trk retrograde signaling requires persistent, Pincher-directed endosomes
@en
Trk retrograde signaling requires persistent, Pincher-directed endosomes
@nl
type
label
Trk retrograde signaling requires persistent, Pincher-directed endosomes
@ast
Trk retrograde signaling requires persistent, Pincher-directed endosomes
@en
Trk retrograde signaling requires persistent, Pincher-directed endosomes
@nl
prefLabel
Trk retrograde signaling requires persistent, Pincher-directed endosomes
@ast
Trk retrograde signaling requires persistent, Pincher-directed endosomes
@en
Trk retrograde signaling requires persistent, Pincher-directed endosomes
@nl
P2093
P2860
P356
P1476
Trk retrograde signaling requires persistent, Pincher-directed endosomes
@en
P2093
Gregorio Valdez
Howard J Federoff
Polyxeni Philippidou
Simon Halegoua
Wendy Akmentin
William J Bowers
P2860
P304
P356
10.1073/PNAS.1015981108
P407
P577
2010-12-27T00:00:00Z