Role for topoisomerase 1 in transcription-associated mutagenesis in yeast
about
The yeast environmental stress response regulates mutagenesis induced by proteotoxic stressGenome-destabilizing effects associated with top1 loss or accumulation of top1 cleavage complexes in yeastFrequency of intron loss correlates with processed pseudogene abundance: a novel strategy to test the reverse transcriptase model of intron lossRibonucleotides in DNA: Origins, repair and consequencesProcessing ribonucleotides incorporated during eukaryotic DNA replication.Yeast Sub1 and human PC4 are G-quadruplex binding proteins that suppress genome instability at co-transcriptionally formed G4 DNASingle-cell nucleosome mapping reveals the molecular basis of gene expression heterogeneityThe Anthropocene: conceptual and historical perspectives.Are there pre-Quaternary geological analogues for a future greenhouse warming?Anthropogenic transformation of the terrestrial biosphere.Why eukaryotic cells use introns to enhance gene expression: splicing reduces transcription-associated mutagenesis by inhibiting topoisomerase I cutting activity.Mutagenic processing of ribonucleotides in DNA by yeast topoisomerase ITopoisomerase 1 provokes the formation of short deletions in repeated sequences upon high transcription in Saccharomyces cerevisiae.All tangled up: how cells direct, manage and exploit topoisomerase function.Molecular biology. A new twist for topoisomerase.Decrease in topoisomerase I is responsible for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation.Error-free and mutagenic processing of topoisomerase 1-provoked damage at genomic ribonucleotidesNonimmunoglobulin target loci of activation-induced cytidine deaminase (AID) share unique features with immunoglobulin genesTranscription as a source of genome instability.Topoisomerase 1-dependent deletions initiated by incision at ribonucleotides are biased to the non-transcribed strand of a highly activated reporter.Nascent RNA folding mitigates transcription-associated mutagenesisGenomic evidence for elevated mutation rates in highly expressed genesHuman DNA polymerase ε is able to efficiently extend from multiple consecutive ribonucleotides.Topoisomerase IIβ deficiency enhances camptothecin-induced apoptosis.Topoisomerase 1-mediated removal of ribonucleotides from nascent leading-strand DNAHigh levels of transcription stimulate transversions at GC base pairs in yeast.Parallel analysis of ribonucleotide-dependent deletions produced by yeast Top1 in vitro and in vivoDetermining the size-dependent structure of ligand-free gold-cluster ions.On the application potential of gold nanoparticles in nanoelectronics and biomedicine.The intertwined roles of transcription and repair proteins.The contribution of co-transcriptional RNA:DNA hybrid structures to DNA damage and genome instability.Transcription and recombination: when RNA meets DNA.Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomic instabilityTopoisomerase-mediated chromosomal break repair: an emerging player in many games.RNA Processing and Genome Stability: Cause and Consequence.SMRT Sequencing for Parallel Analysis of Multiple Targets and Accurate SNP Phasing.Ribonucleotides and Transcription-Associated Mutagenesis in Yeast.The Top1 paradox: Friend and foe of the eukaryotic genome.Anthropogenic modification of the oceans.Anthropocene streams and base-level controls from historic dams in the unglaciated mid-Atlantic region, USA.
P2860
Q28535023-F6CBF49F-BD95-4CB5-9636-159F55CBC9D5Q28545243-9750B461-B955-4DEA-AB3D-D30F06FF4DD8Q28703895-420083AC-8913-4A93-9E33-230518F54E8CQ30047225-86C42C70-DE36-406F-B1CB-972FB3DBCCCDQ33731381-63B1F704-AA93-4D11-AB7B-06CF30859D52Q33741063-98D37C4B-C089-4D59-A6F7-C9EA565A8E96Q33790088-F491059F-A106-4127-ABB7-C5B062A58910Q33808103-1AFB4C72-C73B-4D65-ABDF-F02768373430Q33808112-7F2BB931-A68E-412D-BF48-04B47A7016E1Q33808118-2A40B7C9-8DB9-47CC-8832-A3A80602FDEEQ33904719-35569296-E63A-46F6-A979-92B4702FE47EQ34195091-E9CA843D-7737-4F95-92F1-7836E8681A50Q34490822-89FA9D7F-26A2-4575-9E91-880AB650986DQ35154537-06F49D6D-7C91-4849-BD82-F04E9379E879Q35209774-BDE01A1C-108A-4D6A-AF7D-33670A9DF7FCQ35585876-66AD2A00-1895-4FDB-A242-92CEB48EE242Q35590405-68CEEB09-66BF-4F09-BA30-6AA3CD2798A4Q35786869-71CCD60F-7792-4D54-978A-566D41D0480EQ36036444-5E60868F-6814-4241-87CE-54EC5842AF10Q36228037-4C77C554-BA8B-40ED-8E4E-D2720B7F7019Q36406079-B555C311-CE08-4AF7-B337-7789C8AC0532Q36440506-1D30E728-575F-46E4-8671-842D5E643BD1Q36466634-45EE88F6-302E-40DA-927F-C391D3B6E3F9Q36666233-114C88CA-099D-450E-9E08-A6B39D9FB186Q36677913-28158F5A-4D91-483C-81F5-0B2E0B6699CBQ37237061-F2482213-D4D1-498B-8827-CF0399923927Q37264346-A9392667-7498-433F-8FFD-4ACC1DDAF1C3Q37692686-1E792B54-08A1-44CF-8E71-50A718FFB167Q37692692-63B7503F-7B0D-4040-AA34-1C295BC7E3A5Q38160983-D678D443-5311-4D2D-9E07-DF7A4208EB91Q38205642-AD3082ED-AF1A-433D-86CD-C663949C618BQ38236218-D4D60E39-EC4B-4D35-A3D8-E8860CF9A605Q38266781-EF479A8E-407A-4BC9-B0F2-8DABF5EA8547Q38360744-72814BA3-DCB2-4BE6-BBDD-B3F28F3400DFQ38741213-9E0D50B0-3611-48DE-8162-7D30D66080EFQ38825456-1AD7B6FB-4EDE-4D3C-82EC-2175F7B82BDCQ38924325-2FFE8F31-CF35-4AE3-AE9A-DAB003164B31Q39392249-836E1B84-282D-485B-8A9F-DF5556ACEF3CQ39787905-E8863233-7967-4A61-9286-C0A248801C33Q39968923-02E0FBA8-28EE-47C0-AE50-F280061F0C41
P2860
Role for topoisomerase 1 in transcription-associated mutagenesis in yeast
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Role for topoisomerase 1 in transcription-associated mutagenesis in yeast
@ast
Role for topoisomerase 1 in transcription-associated mutagenesis in yeast
@en
Role for topoisomerase 1 in transcription-associated mutagenesis in yeast
@nl
type
label
Role for topoisomerase 1 in transcription-associated mutagenesis in yeast
@ast
Role for topoisomerase 1 in transcription-associated mutagenesis in yeast
@en
Role for topoisomerase 1 in transcription-associated mutagenesis in yeast
@nl
prefLabel
Role for topoisomerase 1 in transcription-associated mutagenesis in yeast
@ast
Role for topoisomerase 1 in transcription-associated mutagenesis in yeast
@en
Role for topoisomerase 1 in transcription-associated mutagenesis in yeast
@nl
P2093
P2860
P356
P1476
Role for topoisomerase 1 in transcription-associated mutagenesis in yeast
@en
P2093
Jang-Eun Cho
Nathan E Schoenly
Ryan P Larson
Shannon H O'Shea
Sue Jinks-Robertson
P2860
P304
P356
10.1073/PNAS.1012363108
P407
P577
2010-12-21T00:00:00Z