The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells.
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Hallmarks of cancer and AU-rich elementsHuR Contributes to TRAIL Resistance by Restricting Death Receptor 4 Expression in Pancreatic Cancer CellsThe RNA-binding protein LARP1 is a post-transcriptional regulator of survival and tumorigenesis in ovarian cancer.Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis.GC7 blocks epithelial-mesenchymal transition and reverses hypoxia-induced chemotherapy resistance in hepatocellular carcinoma cellsPost-transcriptional regulation of cytokine and growth factor signaling in cancer.Strange Bedfellows: Nuclear Factor, Erythroid 2-Like 2 (Nrf2) and Hypoxia-Inducible Factor 1 (HIF-1) in Tumor Hypoxia.GPRC5A is a potential oncogene in pancreatic ductal adenocarcinoma cells that is upregulated by gemcitabine with help from HuR.HuR-targeted small molecule inhibitor exhibits cytotoxicity towards human lung cancer cells.Tumor-targeted Nanoparticle Delivery of HuR siRNA Inhibits Lung Tumor Growth In Vitro and In Vivo By Disrupting the Oncogenic Activity of the RNA-binding Protein HuR.HistoneH3 demethylase JMJD2A promotes growth of liver cancer cells through up-regulating miR372.Hypoxia-induced oxidative stress promotes MUC4 degradation via autophagy to enhance pancreatic cancer cells survivalPosttranscriptional Upregulation of IDH1 by HuR Establishes a Powerful Survival Phenotype in Pancreatic Cancer Cells.Ancient and modern: hints of a core post-transcriptional network driving chemotherapy resistance in ovarian cancer.Relationship between LAT1 expression and resistance to chemotherapy in pancreatic ductal adenocarcinoma.Elevated HuR in Pancreas Promotes a Pancreatitis-like Inflammatory Microenvironment that Facilitates Tumor Development.CRISPR Knockout of the HuR Gene Causes a Xenograft Lethal Phenotype.Complex HuR function in pancreatic cancer cells.Posttranscriptional Regulation of PARG mRNA by HuR Facilitates DNA Repair and Resistance to PARP Inhibitors.ARE-mediated decay controls gene expression and cellular metabolism upon oxygen variations.Long intergenic non-coding RNA 00324 promotes gastric cancer cell proliferation via binding with HuR and stabilizing FAM83B expression.
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P2860
The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells.
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2015 nî lūn-bûn
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2015 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի սեպտեմբերին հրատարակված գիտական հոդված
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年论文
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name
The mRNA-binding protein HuR p ...... M1 in pancreatic cancer cells.
@ast
The mRNA-binding protein HuR p ...... M1 in pancreatic cancer cells.
@en
The mRNA-binding protein HuR p ...... M1 in pancreatic cancer cells.
@nl
type
label
The mRNA-binding protein HuR p ...... M1 in pancreatic cancer cells.
@ast
The mRNA-binding protein HuR p ...... M1 in pancreatic cancer cells.
@en
The mRNA-binding protein HuR p ...... M1 in pancreatic cancer cells.
@nl
prefLabel
The mRNA-binding protein HuR p ...... M1 in pancreatic cancer cells.
@ast
The mRNA-binding protein HuR p ...... M1 in pancreatic cancer cells.
@en
The mRNA-binding protein HuR p ...... M1 in pancreatic cancer cells.
@nl
P2093
P2860
P356
P1433
P1476
The mRNA-binding protein HuR p ...... IM1 in pancreatic cancer cells
@en
P2093
A K Witkiewicz
E Petricoin
F F Blanco
I Gallagher
J A Sawicki
J M Winter
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P2888
P304
P356
10.1038/ONC.2015.325
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P577
2015-09-21T00:00:00Z
P6179
1031528436