A1 subunit-mediated regulation of thrombin-activated factor VIII A2 subunit dissociation.
about
Development and characterization of recombinant ovine coagulation factor VIIIRegulation of the protein C anticoagulant and antiinflammatory pathways.Role of hydrophobic mutations on the binding affinity and stability of blood coagulation factor VIIIa: a computational molecular dynamics and free-energy analysis.Lentiviral vector platform for production of bioengineered recombinant coagulation factor VIIIFactor VIII A3 domain substitution N1922S results in hemophilia A due to domain-specific misfolding and hyposecretion of functional proteinA major determinant of the immunogenicity of factor VIII in a murine model is independent of its procoagulant function.Antihuman factor VIII C2 domain antibodies in hemophilia A mice recognize a functionally complex continuous spectrum of epitopes dominated by inhibitors of factor VIII activation.The diversity of the immune response to the A2 domain of human factor VIIIContribution of A1 subunit residue Q316 in thrombin-activated factor VIII to A2 subunit dissociation.High-affinity, noninhibitory pathogenic C1 domain antibodies are present in patients with hemophilia A and inhibitors.Enhancing the pharmaceutical properties of protein drugs by ancestral sequence reconstructionIdentification of residues contributing to A2 domain-dependent structural stability in factor VIII and factor VIIIa
P2860
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P2860
A1 subunit-mediated regulation of thrombin-activated factor VIII A2 subunit dissociation.
description
2006 nî lūn-bûn
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2006 թուականի Մարտին հրատարակուած գիտական յօդուած
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2006 թվականի մարտին հրատարակված գիտական հոդված
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2006年の論文
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2006年学术文章
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2006年学术文章
@zh-cn
2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年學術文章
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name
A1 subunit-mediated regulation of thrombin-activated factor VIII A2 subunit dissociation.
@ast
A1 subunit-mediated regulation of thrombin-activated factor VIII A2 subunit dissociation.
@en
A1 subunit-mediated regulation of thrombin-activated factor VIII A2 subunit dissociation.
@nl
type
label
A1 subunit-mediated regulation of thrombin-activated factor VIII A2 subunit dissociation.
@ast
A1 subunit-mediated regulation of thrombin-activated factor VIII A2 subunit dissociation.
@en
A1 subunit-mediated regulation of thrombin-activated factor VIII A2 subunit dissociation.
@nl
prefLabel
A1 subunit-mediated regulation of thrombin-activated factor VIII A2 subunit dissociation.
@ast
A1 subunit-mediated regulation of thrombin-activated factor VIII A2 subunit dissociation.
@en
A1 subunit-mediated regulation of thrombin-activated factor VIII A2 subunit dissociation.
@nl
P2093
P2860
P356
P1476
A1 subunit-mediated regulation of thrombin-activated factor VIII A2 subunit dissociation.
@en
P2093
Christopher B Doering
Ernest T Parker
Pete Lollar
P2860
P304
13922-13930
P356
10.1074/JBC.M513124200
P407
P577
2006-03-02T00:00:00Z