The human orthologue of CdGAP is a phosphoprotein and a GTPase-activating protein for Cdc42 and Rac1 but not RhoA.

The human orthologue of CdGAP is a phosphoprotein and a GTPase-activating protein for Cdc42 and Rac1 but not RhoA.

Item
http://www.wikidata.org/entity/Q34499924
Gain-of-function mutations of ARHGAP31, a Cdc42/Rac1 GTPase regulator, cause syndromic cutis aplasia and limb anomaliesRho GTPase regulation by miRNAs and covalent modificationsRecessive mutations in DOCK6, encoding the guanidine nucleotide exchange factor DOCK6, lead to abnormal actin cytoskeleton organization and Adams-Oliver syndromeCdGAP regulates cell migration and adhesion dynamics in two-and three-dimensional matrix environments.The BNIP-2 and Cdc42GAP homology (BCH) domain of p50RhoGAP/Cdc42GAP sequesters RhoA from inactivation by the adjacent GTPase-activating protein domain.Identification of vascular and hematopoietic genes downstream of etsrp by deep sequencing in zebrafish.A stretch of polybasic residues mediates Cdc42 GTPase-activating protein (CdGAP) binding to phosphatidylinositol 3,4,5-trisphosphate and regulates its GAP activity.Current knowledge of the large RhoGAP family of proteins.CdGAP/ARHGAP31, a Cdc42/Rac1 GTPase regulator, is critical for vascular development and VEGF-mediated angiogenesis.Novel Genetic Associations and Range of Phenotypes in Children with Disorders of Sex Development and Neurodevelopment: Insights from the Deciphering Developmental Disorders Study.Novel signatures of cancer-associated fibroblasts.The scaffold protein Ajuba suppresses CdGAP activity in epithelia to maintain stable cell-cell contacts.CdGAP/ARHGAP31 is regulated by RSK phosphorylation and binding to 14-3-3β adaptor protein.DOCK6 mutations are responsible for a distinct autosomal-recessive variant of Adams-Oliver syndrome associated with brain and eye anomalies.CdGAP is required for transforming growth factor β- and Neu/ErbB-2-induced breast cancer cell motility and invasion.
P2860

The human orthologue of CdGAP is a phosphoprotein and a GTPase-activating protein for Cdc42 and Rac1 but not RhoA.

Item
http://www.wikidata.org/entity/Q34499924
description
2006 nî lūn-bûn
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2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2006 թվականի օգոստոսին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
@yue
2006年論文
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2006年論文
@zh-hk
2006年論文
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2006年論文
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2006年论文
@wuu
name
The human orthologue of CdGAP ...... r Cdc42 and Rac1 but not RhoA.
@ast
The human orthologue of CdGAP ...... r Cdc42 and Rac1 but not RhoA.
@en
The human orthologue of CdGAP ...... r Cdc42 and Rac1 but not RhoA.
@nl
type
label
The human orthologue of CdGAP ...... r Cdc42 and Rac1 but not RhoA.
@ast
The human orthologue of CdGAP ...... r Cdc42 and Rac1 but not RhoA.
@en
The human orthologue of CdGAP ...... r Cdc42 and Rac1 but not RhoA.
@nl
prefLabel
The human orthologue of CdGAP ...... r Cdc42 and Rac1 but not RhoA.
@ast
The human orthologue of CdGAP ...... r Cdc42 and Rac1 but not RhoA.
@en
The human orthologue of CdGAP ...... r Cdc42 and Rac1 but not RhoA.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P356
P1433
P1476
The human orthologue of CdGAP ...... r Cdc42 and Rac1 but not RhoA.
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P698