CD83 increases MHC II and CD86 on dendritic cells by opposing IL-10-driven MARCH1-mediated ubiquitination and degradation. - Wikidata - wikimedia - TriplyDB

CD83 increases MHC II and CD86 on dendritic cells by opposing IL-10-driven MARCH1-mediated ubiquitination and degradation.

CD83 increases MHC II and CD86 on dendritic cells by opposing IL-10-driven MARCH1-mediated ubiquitination and degradation.

http://www.wikidata.org/entity/Q34501441

about

Ubiquitination of human leukocyte antigen (HLA)-DM by different membrane-associated RING-CH (MARCH) protein family E3 ligases targets different endocytic pathways Ubiquitin signaling in immune responses The role of ubiquitylation in immune defence and pathogen evasion Molecular mechanism and cellular function of MHCII ubiquitination Size-dependent effects of gold nanoparticles uptake on maturation and antitumor functions of human dendritic cells in vitro Silencing MARCH1 suppresses proliferation, migration and invasion of ovarian cancer SKOV3 cells via downregulation of NF-κB and Wnt/β-catenin pathways Dissecting mammalian immunity through mutation.Diametric Role of the Latency-Associated Protein Acr1 of Mycobacterium tuberculosis in Modulating the Functionality of Pre- and Post-maturational Stages of Dendritic Cells.Ubiquitous points of control over regulatory T cells.BCG vaccine mediated reduction in the MHC-II expression of macrophages and dendritic cells is reversed by activation of Toll-like receptors 7 and 9.Francisella tularensis elicits IL-10 via a PGE₂-inducible factor, to drive macrophage MARCH1 expression and class II down-regulation.Dendritic cell maturation: functional specialization through signaling specificity and transcriptional programming Suppression of antigen presentation by IL-10 Hrd1-mediated BLIMP-1 ubiquitination promotes dendritic cell MHCII expression for CD4 T cell priming during inflammation.Dendritic cell CD83 homotypic interactions regulate inflammation and promote mucosal homeostasis Class-switched memory B cells remodel BCRs within secondary germinal centers.CD11c controls herpes simplex virus 1 responses to limit virus replication during primary infection.Ubiquitination of CD86 is a key mechanism in regulating antigen presentation by dendritic cells.Autoregulatory function of interleukin-10-producing pre-naïve B cells is defective in systemic lupus erythematosus Continuous expression of CD83 on activated human CD4⁺ T cells is correlated with their differentiation into induced regulatory T cells Interleukin 10 (IL-10)-mediated Immunosuppression: MARCH-I INDUCTION REGULATES ANTIGEN PRESENTATION BY MACROPHAGES BUT NOT DENDRITIC CELLS LLT1 and CD161 Expression in Human Germinal Centers Promotes B Cell Activation and CXCR4 Downregulation.MARCH1-mediated MHCII ubiquitination promotes dendritic cell selection of natural regulatory T cells Ubiquitin-mediated fluctuations in MHC class II facilitate efficient germinal center B cell responses.Ubiquitin ligase MARCH 8 cooperates with CD83 to control surface MHC II expression in thymic epithelium and CD4 T cell selection Thymic CD4 T cell selection requires attenuation of March8-mediated MHCII turnover in cortical epithelial cells through CD83.Regulation of MHC Class II-Peptide Complex Expression by Ubiquitination.Antigen-specific induced T regulatory cells impair dendritic cell function via an IL-10/MARCH1-dependent mechanism tTregs, pTregs, and iTregs: similarities and differences.Endosomal transport via ubiquitination MHC class II antigen presentation by dendritic cells regulated through endosomal sorting.The Role of the Transmembrane RING Finger Proteins in Cellular and Organelle Function Differentiation and activation of equine monocyte-derived dendritic cells are not correlated with CD206 or CD83 expression.The ins and outs of MHC class II-mediated antigen processing and presentation.The Membrane Associated RING-CH Proteins: A Family of E3 Ligases with Diverse Roles through the Cell.Ubiquitination by the membrane-associated RING-CH-8 (MARCH-8) ligase controls steady-state cell surface expression of tumor necrosis factor-related apoptosis inducing ligand (TRAIL) receptor 1.A new marine-derived sulfoglycolipid triggers dendritic cell activation and immune adjuvant response.The Nucleocapsid Protein and Nonstructural Protein 10 of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Enhance CD83 Production via NF-κB and Sp1 Signaling Pathways.Murine LRBA deficiency causes CTLA-4 deficiency in Tregs without progression to immune dysregulation.MARCH1 E3 Ubiquitin Ligase Dampens the Innate Inflammatory Response by Modulating Monocyte Functions in Mice.

P2860

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P2860

CD83 increases MHC II and CD86 on dendritic cells by opposing IL-10-driven MARCH1-mediated ubiquitination and degradation.

http://www.wikidata.org/entity/Q34501441

description

2011 nî lūn-bûn

@nan

2011 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2011年の論文

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2011年論文

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2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

CD83 increases MHC II and CD86 ...... biquitination and degradation.

@ast

CD83 increases MHC II and CD86 ...... biquitination and degradation.

@en

CD83 increases MHC II and CD86 ...... biquitination and degradation.

@nl

type

label

CD83 increases MHC II and CD86 ...... biquitination and degradation.

@ast

CD83 increases MHC II and CD86 ...... biquitination and degradation.

@en

CD83 increases MHC II and CD86 ...... biquitination and degradation.

@nl

prefLabel

CD83 increases MHC II and CD86 ...... biquitination and degradation.

@ast

CD83 increases MHC II and CD86 ...... biquitination and degradation.

@en

CD83 increases MHC II and CD86 ...... biquitination and degradation.

@nl

P1433

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P1433

Journal of Experimental Medicine

P1476

CD83 increases MHC II and CD86 ...... ubiquitination and degradation

@en

P2093

Carla M Roots

http://www.w3.org/2001/XMLSchema#string

David A Way

http://www.w3.org/2001/XMLSchema#string

Debbie R Howard

http://www.w3.org/2001/XMLSchema#string

Heather Domaschenz

http://www.w3.org/2001/XMLSchema#string

Lina E Tze

http://www.w3.org/2001/XMLSchema#string

Mari Ohmura-Hoshino

http://www.w3.org/2001/XMLSchema#string

Mariapia A Degli-Esposti

http://www.w3.org/2001/XMLSchema#string

Satoshi Ishido

http://www.w3.org/2001/XMLSchema#string

P2860

A novel cell-surface molecule expressed by human interdigitating reticulum cells, Langerhans cells, and activated lymphocytes is a new member of the Ig superfamily

Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins

Interleukin-10-induced MARCH1 mediates intracellular sequestration of MHC class II in monocytes

MHC class II stabilization at the surface of human dendritic cells is the result of maturation-dependent MARCH I down-regulation

Potent immunosuppressive activities of cytomegalovirus-encoded interleukin-10

Inhibition of MHC class II expression and immune responses by c-MIR

A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity

Novel regulation of MHC class II function in B cells

Mice lacking MHC class II molecules

A novel mutation in CD83 results in the development of a unique population of CD4+ T cells

P304

149-165

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P31

scholarly article

P356

10.1084/JEM.20092203

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P407

P433

1

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P478

208

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P50

Christopher E Andoniou

Keisuke Horikawa

Christopher C. Goodnow

P577

2011-01-10T00:00:00Z

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P5875

49742049

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P698

21220452

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P921

protein ubiquitination

P932

3023131

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