RebG- and RebM-catalyzed indolocarbazole diversification. - Wikidata - wikimedia - TriplyDB

RebG- and RebM-catalyzed indolocarbazole diversification.

RebG- and RebM-catalyzed indolocarbazole diversification.

http://www.wikidata.org/entity/Q34507343

about

Structure and mechanism of the rebeccamycin sugar 4'-O-methyltransferase RebM Crystallographic trapping in the rebeccamycin biosynthetic enzyme RebC Structural characterization of the mitomycin 7-O-methyltransferase Structural and functional insight into an unexpectedly selective N-methyltransferase involved in plantazolicin biosynthesis Facile chemoenzymatic strategies for the synthesis and utilization of S-adenosyl-(L)-methionine analogues Enzymatic methods for glyco(diversification/randomization) of drugs and small molecules Natural-product sugar biosynthesis and enzymatic glycodiversification.Biosynthetic gene cluster for the cladoniamides, bis-indoles with a rearranged scaffold.Pseudoglycosyltransferase catalyzes nonglycosidic C-N coupling in validamycin a biosynthesis Probing the aglycon promiscuity of an engineered glycosyltransferase Genetic insights into pyralomicin biosynthesis in Nonomuraea spiralis IMC A-0156.Indolocarbazole natural products: occurrence, biosynthesis, and biological activity.Divergent pathways in the biosynthesis of bisindole natural products.Enzymatic methylation and structure-activity-relationship studies on polycarcin V, a gilvocarcin-type antitumor agent.Discovery and synthetic refactoring of tryptophan dimer gene clusters from the environment Characterization of an environmental DNA-derived gene cluster that encodes the bisindolylmaleimide methylarcyriarubin Structural basis of substrate specificity and regiochemistry in the MycF/TylF family of sugar O-methyltransferases.Cytotoxic Indolocarbazoles from Actinomadura melliaura ATCC 39691 A comprehensive review of glycosylated bacterial natural products.Insights into methyltransferase specificity and bioactivity of derivatives of the antibiotic plantazolicin Regiospecific O-methylation of naphthoic acids catalyzed by NcsB1, an O-methyltransferase involved in the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin Biosynthesis of indolocarbazole and goadsporin, two different heterocyclic antibiotics produced by actinomycetes.Glycosyltransferases: mechanisms and applications in natural product development.Expansion of bisindole biosynthetic pathways by combinatorial construction.Identification and characterization of a biosynthetic gene cluster for tryptophan dimers in deep sea-derived Streptomyces sp. SCSIO 03032.Characterization of the sugar-O-methyltransferase LobS1 in lobophorin biosynthesis.Identification and characterization of a welwitindolinone alkaloid biosynthetic gene cluster in the stigonematalean Cyanobacterium Hapalosiphon welwitschii.Spectral Analysis and Crystal Structures of 4-(4-Methylphenyl)-6-Phenyl-2,3,3a, 4-Tetrahydro-1H-Pyrido[3,2,1-jk]Carbazole and 4-(4-Methoxyphenyl)-6-Phenyl-2,3,3a, 4-Tetrahydro-1H-Pyrido[3,2,1-jk]Carbazole.OleD Loki as a Catalyst for Tertiary Amine and Hydroxamate Glycosylation.Analysis of a parallel branch in the mitomycin biosynthetic pathway involving the mitN-encoded aziridine N-methyltransferase.Characterization of a Sugar-O-methyltransferase TiaS5 Affords New Tiacumicin Analogues with Improved Antibacterial Properties and Reveals Substrate Promiscuity

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P2860

RebG- and RebM-catalyzed indolocarbazole diversification.

http://www.wikidata.org/entity/Q34507343

description

2006 nî lūn-bûn

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2006 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2006 թվականի մայիսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

RebG- and RebM-catalyzed indolocarbazole diversification.

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RebG- and RebM-catalyzed indolocarbazole diversification.

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RebG- and RebM-catalyzed indolocarbazole diversification.

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type

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RebG- and RebM-catalyzed indolocarbazole diversification.

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RebG- and RebM-catalyzed indolocarbazole diversification.

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RebG- and RebM-catalyzed indolocarbazole diversification.

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RebG- and RebM-catalyzed indolocarbazole diversification.

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RebG- and RebM-catalyzed indolocarbazole diversification.

@en

RebG- and RebM-catalyzed indolocarbazole diversification.

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RebG- and RebM-catalyzed indolocarbazole diversification.

@en

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Changsheng Zhang

http://www.w3.org/2001/XMLSchema#string

Christoph Albermann

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David L Van Vranken

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Eric J Gilbert

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Guisheng Zhang

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John D Chisholm

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Jon S Thorson

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Noel R Peters

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Peng George Wang

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Xun Fu

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P2860

Molecular analysis of the rebeccamycin L-amino acid oxidase from Lechevalieria aerocolonigenes ATCC 39243

Robust in vitro activity of RebF and RebH, a two-component reductase/halogenase, generating 7-chlorotryptophan during rebeccamycin biosynthesis

Combinatorial biosynthesis of antitumor indolocarbazole compounds

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Neoglycorandomization and chemoenzymatic glycorandomization: two complementary tools for natural product diversification

Functional analysis of OleY L-oleandrosyl 3-O-methyltransferase of the oleandomycin biosynthetic pathway in Streptomyces antibioticus

Regiocontrolled synthesis of the antitumor antibiotic AT2433-A1.

Recent developments of rebeccamycin analogues as topoisomerase I inhibitors and antitumor agents.

Enzymatic approach to unnatural glycosides with diverse aglycon scaffolds using glycosyltransferase VinC.

Novel avilamycin derivatives with improved polarity generated by targeted gene disruption.

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795-804

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10.1002/CBIC.200500504

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5

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7

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2006-05-01T00:00:00Z

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16575939

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