Intracellular ubiquitylation of the epithelial Na+ channel controls extracellular proteolytic channel activation via conformational change.
about
Regulation and dysregulation of epithelial Na+ channelsUrinary Proteolytic Activation of Renal Epithelial Na+ Channels in Chronic Heart Failure.Delivery of ENaC siRNA to epithelial cells mediated by a targeted nanocomplex: a therapeutic strategy for cystic fibrosis.The N-terminal domain allosterically regulates cleavage and activation of the epithelial sodium channel.Genetic screening of SCNN1B and SCNN1G genes in early-onset hypertensive patients helps to identify Liddle syndrome.Acetylation stimulates the epithelial sodium channel by reducing its ubiquitination and degradationFeedback inhibition of ENaC: acute and chronic mechanismsUbiquitin-specific peptidase 8 (USP8) regulates endosomal trafficking of the epithelial Na+ channelSMURF and NEDD4: sharp shooters monitor the gate keepers and ion traffic controllers of lead astray cell.Renal tubular SGK1 deficiency causes impaired K+ excretion via loss of regulation of NEDD4-2/WNK1 and ENaC.Interacting domains in the epithelial sodium channel that mediate proteolytic activation.Mice carrying ubiquitin-specific protease 2 (Usp2) gene inactivation maintain normal sodium balance and blood pressure.
P2860
Q28251865-3A15AC2F-2C44-4FE5-B7DF-573A7B053F66Q30315923-0C17215D-38D4-4E10-848B-B24239CACBABQ33674129-893B99D6-7E33-4AF0-A2FA-38AF54B7BDF2Q34044713-D362B186-4431-4A4C-8518-7BE1BA8C0BE9Q34682504-A831F6D5-D969-43DA-B7FD-DF60005C6100Q35608048-76F4C009-0FA8-4365-A1A0-8B7166A806D4Q36125106-B074000B-636A-48E9-B9D0-DCB0B82BE97DQ36635913-8F8B1210-0E36-42B4-B449-FD11A98DD769Q37932428-A946C393-FE05-4F30-9942-6C8ECAE92686Q39893074-000D4E6D-97C0-4B71-978E-779B3B8EB731Q39994474-2000A600-6FE2-4E41-BBC2-CAFE04C22EBCQ43807758-89FBC423-621A-4AF2-98D5-C86696B705DB
P2860
Intracellular ubiquitylation of the epithelial Na+ channel controls extracellular proteolytic channel activation via conformational change.
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Intracellular ubiquitylation o ...... ion via conformational change.
@ast
Intracellular ubiquitylation o ...... ion via conformational change.
@en
Intracellular ubiquitylation o ...... ion via conformational change.
@nl
type
label
Intracellular ubiquitylation o ...... ion via conformational change.
@ast
Intracellular ubiquitylation o ...... ion via conformational change.
@en
Intracellular ubiquitylation o ...... ion via conformational change.
@nl
prefLabel
Intracellular ubiquitylation o ...... ion via conformational change.
@ast
Intracellular ubiquitylation o ...... ion via conformational change.
@en
Intracellular ubiquitylation o ...... ion via conformational change.
@nl
P2860
P356
P1476
Intracellular ubiquitylation o ...... ion via conformational change.
@en
P2093
Dorothée Ruffieux-Daidié
Olivier Staub
P2860
P304
P356
10.1074/JBC.M110.176156
P407
P577
2010-11-17T00:00:00Z