The purinergic receptor P2X7 triggers alpha-secretase-dependent processing of the amyloid precursor protein - Wikidata - wikimedia - TriplyDB

The purinergic receptor P2X7 triggers alpha-secretase-dependent processing of the amyloid precursor protein

The purinergic receptor P2X7 triggers alpha-secretase-dependent processing of the amyloid precursor protein

http://www.wikidata.org/entity/Q34509353

about

Role of P2X7 and P2Y2 receptors on α-secretase-dependent APP processing: Control of amyloid plaques formation "in vivo" by P2X7 receptor Neuronal and glial purinergic receptors functions in neuron development and brain disease Pathophysiology of astroglial purinergic signalling Regulation of amyloid precursor protein processing by serotonin signaling The role of nucleotides and purinergic signaling in apoptotic cell clearance - implications for chronic inflammatory diseases.P2X7 receptor-mediated scavenger activity of mononuclear phagocytes toward non-opsonized particles and apoptotic cells is inhibited by serum glycoproteins but remains active in cerebrospinal fluid.P2 receptors and immunity.Alterations in metabolic pathways and networks in Alzheimer's disease miR-186 is decreased in aged brain and suppresses BACE1 expression Post-translational allosteric activation of the P2X7 receptor through glycosaminoglycan chains of CD44 proteoglycans Modulation of GSK-3 as a Therapeutic Strategy on Tau Pathologies.Identification and biology of α-secretase.Perspectives of purinergic signaling in stem cell differentiation and tissue regeneration.Neurotransmitter signaling in the pathophysiology of microglia.P2X and P2Y receptors—role in the pathophysiology of the nervous system.Roles of extracellular nucleotides and P2 receptors in ectodomain shedding.Ezrin/radixin/moesin are required for the purinergic P2X7 receptor (P2X7R)-dependent processing of the amyloid precursor protein.Opposite effects of P2X7 and P2Y2 nucleotide receptors on α-secretase-dependent APP processing in Neuro-2a cells.Astroglial connexin43 contributes to neuronal suffering in a mouse model of Alzheimer's disease P2X7 receptor activity regulation: the role of CD44 proteoglycan GAG chains.Purinergic Modulation of Spinal Neuroglial Maladaptive Plasticity Following Peripheral Nerve Injury.P2X receptor overexpression induced by soluble oligomers of amyloid beta peptide potentiates synaptic failure and neuronal dyshomeostasis in cellular models of Alzheimer's disease.Effects of aluminium on β-amyloid (1-42) and secretases (APP-cleaving enzymes) in rat brain.The P2X7 Receptor in Inflammatory Diseases: Angel or Demon?Surface Trafficking of APP and BACE in Live Cells.Variations in Cellular Responses of Mouse T Cells to Adenosine-5'-Triphosphate Stimulation Do Not Depend on P2X7 Receptor Expression Levels but on Their Activation and Differentiation Stage.

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P2860

The purinergic receptor P2X7 triggers alpha-secretase-dependent processing of the amyloid precursor protein

http://www.wikidata.org/entity/Q34509353

description

2010 nî lūn-bûn

@nan

2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

The purinergic receptor P2X7 t ...... the amyloid precursor protein

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The purinergic receptor P2X7 t ...... the amyloid precursor protein

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The purinergic receptor P2X7 t ...... the amyloid precursor protein

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type

label

The purinergic receptor P2X7 t ...... the amyloid precursor protein

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The purinergic receptor P2X7 t ...... the amyloid precursor protein

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The purinergic receptor P2X7 t ...... the amyloid precursor protein

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prefLabel

The purinergic receptor P2X7 t ...... the amyloid precursor protein

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The purinergic receptor P2X7 t ...... the amyloid precursor protein

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The purinergic receptor P2X7 t ...... the amyloid precursor protein

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JBC.M110.200618

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Journal of Biological Chemistry

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The purinergic receptor P2X7 t ...... the amyloid precursor protein

@en

P2093

Bertrand Fontaine

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Cécile Delarasse

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Jean M Kanellopoulos

http://www.w3.org/2001/XMLSchema#string

Pauline Gonnord

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Rodolphe Auger

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P2860

Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors

The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts

A novel sorting nexin modulates endocytic trafficking and alpha-secretase cleavage of the amyloid precursor protein

Extracellular signal-regulated kinase phosphorylates tumor necrosis factor alpha-converting enzyme at threonine 735: a potential role in regulated shedding.

Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

A loss-of-function polymorphic mutation in the cytolytic P2X7 receptor gene and chronic lymphocytic leukaemia: a molecular study

The neuropeptide PACAP promotes the alpha-secretase pathway for processing the Alzheimer amyloid precursor protein

Signaling at purinergic P2X receptors

A role for mitogen-activated protein kinase(Erk1/2) activation and non-selective pore formation in P2X7 receptor-mediated thymocyte death

Coupling of two pools of P2X7 receptors to distinct intracellular signaling pathways in rat submandibular gland

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2596-2606

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scholarly article

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10.1074/JBC.M110.200618

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4

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286

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2010-11-16T00:00:00Z

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21081501

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3024755

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