PD-1 immune checkpoint blockade reduces pathology and improves memory in mouse models of Alzheimer's disease.
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Drug Repositioning for Alzheimer's Disease Based on Systematic 'omics' Data MiningExploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies: A convening of the Alzheimer's Association & Alzheimer's Drug Discovery Foundation.Lymphatics in Neurological Disorders: A Neuro-Lympho-Vascular Component of Multiple Sclerosis and Alzheimer's Disease?Multifaceted interactions between adaptive immunity and the central nervous system.Immune Checkpoint in Glioblastoma: Promising and ChallengingChronic Toxoplasma gondii infection enhances β-amyloid phagocytosis and clearance by recruited monocytes.The retinal pigment epithelium as a gateway for monocyte trafficking into the eye.Molecular and genetic inflammation networks in major human diseases.The multi-target effects of CNI-1493: convergence of anti-amylodogenic and anti-inflammatory properties in animal models of Alzheimer's diseaseAre immune checkpoint blockade monoclonal antibodies active against CNS metastases from NSCLC?-current evidence and future perspectives.T Lymphocytes and Inflammatory Mediators in the Interplay between Brain and Blood in Alzheimer's Disease: Potential Pools of New Biomarkers.Dissecting Amyloid Beta Deposition Using Distinct Strains of the Neurotropic Parasite Toxoplasma gondii as a Novel Tool.Inhibitors of programmed cell death 1 (PD-1): a patent review (2010-2015).Cytokine networks in neuroinflammation.Interleukin-2 improves amyloid pathology, synaptic failure and memory in Alzheimer's disease mice.Clearance of cerebral Aβ in Alzheimer's disease: reassessing the role of microglia and monocytes.Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathyMicrobial Immuno-Communication in Neurodegenerative DiseasesModulation of innate immunity of patients with Alzheimer's disease by omega-3 fatty acids.The roles of the PD-1/PD-L1 pathway at immunologically privileged sites.Amyloid beta: structure, biology and structure-based therapeutic development.Targeting neuroinflammation in Alzheimer's disease: evidence for NSAIDs and novel therapeutics.In situ and in silico kinetic analyses of programmed cell death-1 (PD-1) receptor, programmed cell death ligands, and B7-1 protein interaction network.Are We Moving Closer to Noninvasive Imaging and Monitoring of Neonatal Anesthesia-induced Neurotoxicity?Antibiotic-induced perturbations in microbial diversity during post-natal development alters amyloid pathology in an aged APPSWE/PS1ΔE9 murine model of Alzheimer's disease.Choroid plexus-cerebrospinal fluid route for monocyte-derived macrophages after stroke.Combination of Aβ Suppression and Innate Immune Activation in the Brain Significantly Attenuates Amyloid Plaque Deposition.Hepcidin attenuates amyloid beta-induced inflammatory and pro-oxidant responses in astrocytes and microglia.Autoimmunity as a Driving Force of Cognitive Evolution.Etiogenic factors present in the cerebrospinal fluid from amyotrophic lateral sclerosis patients induce predominantly pro-inflammatory responses in microglia.Targeting Neuroinflammation to Treat Alzheimer's Disease.Glial Draper Rescues Aβ Toxicity in a Drosophila Model of Alzheimer's Disease.Systemic immune-checkpoint blockade with anti-PD1 antibodies does not alter cerebral amyloid-β burden in several amyloid transgenic mouse models.Th17 cells in depression.Anti-PD-1/anti-CTLA-4 efficacy in melanoma brain metastases depends on extracranial disease and augmentation of CD8+ T cell trafficking.CNS side effects of immune checkpoint inhibitors: preclinical models, genetics and multimodality therapy.Inflammatory CNS disease caused by immune checkpoint inhibitors: status and perspectives.Can immunotherapy treat neurodegeneration?Central Regulation of Glucose Homeostasis.Neurodegenerative disease: Immunotherapy opportunity emerges for Alzheimer disease.
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PD-1 immune checkpoint blockade reduces pathology and improves memory in mouse models of Alzheimer's disease.
description
2016 nî lūn-bûn
@nan
2016 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
PD-1 immune checkpoint blockad ...... models of Alzheimer's disease.
@ast
PD-1 immune checkpoint blockad ...... models of Alzheimer's disease.
@en
PD-1 immune checkpoint blockad ...... models of Alzheimer's disease.
@nl
type
label
PD-1 immune checkpoint blockad ...... models of Alzheimer's disease.
@ast
PD-1 immune checkpoint blockad ...... models of Alzheimer's disease.
@en
PD-1 immune checkpoint blockad ...... models of Alzheimer's disease.
@nl
prefLabel
PD-1 immune checkpoint blockad ...... models of Alzheimer's disease.
@ast
PD-1 immune checkpoint blockad ...... models of Alzheimer's disease.
@en
PD-1 immune checkpoint blockad ...... models of Alzheimer's disease.
@nl
P2093
P2860
P50
P356
P1433
P1476
PD-1 immune checkpoint blockad ...... models of Alzheimer's disease.
@en
P2093
Afroditi Tsitsou-Kampeli
Alaa Mohammad Sharif
Aleksandra Deczkowska
Alexander Kertser
Eyal David
Kuti Baruch
Michal Schwartz
Neta Rosenzweig
Orit Matcovitch-Natan
P2860
P2888
P304
P356
10.1038/NM.4022
P407
P577
2016-01-18T00:00:00Z