Activity and mechanism of action of N-methanocarbathymidine against herpesvirus and orthopoxvirus infections.
about
A Nucleotide-Analogue-Induced Gain of Function Corrects the Error-Prone Nature of Human DNA Polymerase iotaStructure of vaccinia virus thymidine kinase in complex with dTTP: insights for drug designA greener enantioselective synthesis of the antiviral agent North-methanocarbathymidine (N-MCT) from 2-deoxy-d-ribose.Cyclopropavir inhibits the normal function of the human cytomegalovirus UL97 kinase.CMX001 potentiates the efficacy of acyclovir in herpes simplex virus infectionsN-Methanocarbathymidine is more effective than acyclovir for treating neonatal herpes simplex virus infection in guinea pigsEfficacy of delayed treatment with ST-246 given orally against systemic orthopoxvirus infections in miceSelective phosphorylation of antiviral drugs by vaccinia virus thymidine kinase.Synergistic efficacy of the combination of ST-246 with CMX001 against orthopoxviruses.Efficacy of N-methanocarbathymidine in treating mice infected intranasally with the IHD and WR strains of vaccinia virusVaccinia virus lacking the deoxyuridine triphosphatase gene (F2L) replicates well in vitro and in vivo, but is hypersensitive to the antiviral drug (N)-methanocarbathymidineHuman cytomegalovirus UL97 kinase alters the accumulation of CDK1.Human cytomegalovirus UL97 kinase activity is required for the hyperphosphorylation of retinoblastoma protein and inhibits the formation of nuclear aggresomes.Treatment of herpes simplex virus infections in pediatric patients: current status and future needs.Therapeutic and prophylactic drugs to treat orthopoxvirus infectionsSynthesis and antiviral activities of methylenecyclopropane analogs with 6-alkoxy and 6-alkylthio substitutions that exhibit broad-spectrum antiviral activity against human herpesviruses.Activities of certain 5-substituted 4'-thiopyrimidine nucleosides against orthopoxvirus infections.Novel biotinylated lipid prodrugs of acyclovir for the treatment of herpetic keratitis (HK): transporter recognition, tissue stability and antiviral activityOrthopoxvirus targets for the development of new antiviral agents.Progress in the discovery of compounds inhibiting orthopoxviruses in animal models.Inhibition of herpesvirus replication by 5-substituted 4'-thiopyrimidine nucleosides.Highlights in antiviral drug research: antivirals at the horizon.Helicase-primase as a target of new therapies for herpes simplex virus infections.Antiviral Activity of 4'-thioIDU and Thymidine Analogs against OrthopoxvirusesAntiviral activities and phosphorylation of 5-halo-2'-deoxyuridines and N-methanocarbathymidine in cells infected with vaccinia virus.A rapid DNA hybridization assay for the evaluation of antiviral compounds against Epstein-Barr virus.Synthesis, Characterization, and Biological Evaluation of Some Novel Quinoxaline Derivatives as Antiviral Agents.Efficacy of N-methanocarbathymidine against genital herpes simplex virus type 2 shedding and infection in guinea pigs.Inhibition of Vaccinia virus entry by a broad spectrum antiviral peptide.Design, Synthesis, and Biological Evaluation of γ-Aminopropyl Silatrane-Acyclovir Hybrids with Immunomodulatory Effects.Anti-DNA Virus Agents
P2860
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P2860
Activity and mechanism of action of N-methanocarbathymidine against herpesvirus and orthopoxvirus infections.
description
2006 nî lūn-bûn
@nan
2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Activity and mechanism of acti ...... and orthopoxvirus infections.
@ast
Activity and mechanism of acti ...... and orthopoxvirus infections.
@en
Activity and mechanism of acti ...... and orthopoxvirus infections.
@nl
type
label
Activity and mechanism of acti ...... and orthopoxvirus infections.
@ast
Activity and mechanism of acti ...... and orthopoxvirus infections.
@en
Activity and mechanism of acti ...... and orthopoxvirus infections.
@nl
prefLabel
Activity and mechanism of acti ...... and orthopoxvirus infections.
@ast
Activity and mechanism of acti ...... and orthopoxvirus infections.
@en
Activity and mechanism of acti ...... and orthopoxvirus infections.
@nl
P2093
P2860
P1476
Activity and mechanism of acti ...... and orthopoxvirus infections.
@en
P2093
Debra C Quenelle
Earl R Kern
Kathy A Keith
Mark N Prichard
P2860
P304
P356
10.1128/AAC.50.4.1336-1341.2006
P407
P577
2006-04-01T00:00:00Z