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Multigenic control of disease severity after virulent Mycobacterium tuberculosis infection in mice

Multigenic control of disease severity after virulent Mycobacterium tuberculosis infection in mice

http://www.wikidata.org/entity/Q34521406

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Comparative genomics of Toll-like receptor signalling in five species In mice, tuberculosis progression is associated with intensive inflammatory response and the accumulation of Gr-1 cells in the lungs.Neutrophil responses to Mycobacterium tuberculosis infection in genetically susceptible and resistant mice Fine mapping of Leishmania major susceptibility Locus lmr2 and evidence of a role for Fli1 in disease and wound healing.Alleles of the NRAMP1 gene are risk factors for pediatric tuberculosis disease.Analysis of cellular phenotypes that mediate genetic resistance to tuberculosis using a radiation bone marrow chimera approach The wound repair response controls outcome to cutaneous leishmaniasis.How "humane" is your endpoint? Refining the science-driven approach for termination of animal studies of chronic infection.Animal welfare in studies on murine tuberculosis: assessing progress over a 12-year period and the need for further improvement.Different innate ability of I/St and A/Sn mice to combat virulent Mycobacterium tuberculosis: phenotypes expressed in lung and extrapulmonary macrophages.Multigenic control of tuberculosis resistance: analysis of a QTL on mouse chromosome 7 and its synergism with sst1.Genetic and functional characterization of the mouse Trl3 locus in defense against tuberculosis.Disseminated and rapidly fatal tuberculosis in mice bearing a defective allele at IFN regulatory factor 8.Mouse model of tuberculosis Joint effects of host genetic background and mycobacterial pathogen on susceptibility to infection.Multigenic control and sex bias in host susceptibility to spore-induced pulmonary anthrax in mice Susceptibility to tuberculosis: a locus on mouse chromosome 19 (Trl-4) regulates Mycobacterium tuberculosis replication in the lungs.H-2 alleles contribute to antigen 85-specific interferon-gamma responses during Mycobacterium tuberculosis infection.The QTL within the H2 Complex Involved in the Control of Tuberculosis Infection in Mice Is the Classical Class II H2-Ab1 Gene.Widespread bronchogenic dissemination makes DBA/2 mice more susceptible than C57BL/6 mice to experimental aerosol infection with Mycobacterium tuberculosis I/St mice hypersusceptible to Mycobacterium tuberculosis are resistant to M. avium Fibrotic response as a distinguishing feature of resistance and susceptibility to pulmonary infection with Mycobacterium tuberculosis in mice Mouse models of human TB pathology: roles in the analysis of necrosis and the development of host-directed therapies.The resistance of BALB/cJ mice to Yersinia pestis maps to the major histocompatibility complex of chromosome 17.Man and mouse TB: contradictions and solutions.Progress and new directions in genetics of tuberculosis: an NHLBI working group report.The major histocompatibility complex haplotype affects T-cell recognition of mycobacterial antigens but not resistance to Mycobacterium tuberculosis in C3H mice.Rapid, simple in vivo screen for new drugs active against Mycobacterium tuberculosis Mycobacterium tuberculosis-susceptible I/St mice develop severe disease following infection with taxonomically distant bacteria, Salmonella enterica and Chlamydia pneumoniae.A new coding mutation in the Tnf-alpha leader sequence in tuberculosis-sensitive I/St mice causes higher secretion levels of soluble TNF-alpha.Complex genetic control of susceptibility to Mycobacterium bovis (Bacille Calmette-Guérin) infection in wild-derived Mus spretus mice.Lung cell responses to M. tuberculosis in genetically susceptible and resistant mice following intratracheal challenge.Local and Systemic Immune Responses to Salmonella in Genetically Susceptible I/St Mice after Mucosal Challenge Evaluation of cytotoxicity and genotoxicity of Acacia aroma leaf extracts

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Multigenic control of disease severity after virulent Mycobacterium tuberculosis infection in mice

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2003年の論文

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IAI.71.1.126-131.2003

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Infection and Immunity

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Multigenic control of disease ...... tuberculosis infection in mice

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Alexander S Apt

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Ann-Sophie Persson

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Boris V Nikonenko

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Fabio Sánchez

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Natural resistance to infection with intracellular parasites: isolation of a candidate for Bcg

Effect of oestrogen on Mycobacterium avium complex pulmonary infection in mice

Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations

Influence of vitamin D deficiency and vitamin D receptor polymorphisms on tuberculosis among Gujarati Asians in west London: a case-control study.

Linkage of tuberculosis to chromosome 2q35 loci, including NRAMP1, in a large aboriginal Canadian family.

The battle of two genomes: genetics of bacterial host/pathogen interactions in mice.

Tuberculosis and chronic hepatitis B virus infection in Africans and variation in the vitamin D receptor gene.

Genetic susceptibility to tuberculosis in Africans: a genome-wide scan.

Resistance to Leishmania major is linked to the H2 region on chromosome 17 and to chromosome 9

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Mycobacterium tuberculosis

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