Genomic loss of tumor suppressor miRNA-204 promotes cancer cell migration and invasion by activating AKT/mTOR/Rac1 signaling and actin reorganization - Wikidata - wikimedia - TriplyDB

Genomic loss of tumor suppressor miRNA-204 promotes cancer cell migration and invasion by activating AKT/mTOR/Rac1 signaling and actin reorganization

Genomic loss of tumor suppressor miRNA-204 promotes cancer cell migration and invasion by activating AKT/mTOR/Rac1 signaling and actin reorganization

http://www.wikidata.org/entity/Q34533814

about

Regulatory networks between neurotrophins and miRNAs in brain diseases and cancers The dual regulatory role of miR-204 in cancer Integrated genomic characterization of papillary thyroid carcinoma Insulin promotes glucose consumption via regulation of miR-99a/mTOR/PKM2 pathway Suppression of miR-204 enables oral squamous cell carcinomas to promote cancer stemness, EMT traits, and lymph node metastasis A dual yet opposite growth-regulating function of miR-204 and its target XRN1 in prostate adenocarcinoma cells and neuroendocrine-like prostate cancer cells A Downmodulated MicroRNA Profiling in Patients with Gastric Cancer.Decreased expression of miR-204 is associated with poor prognosis in patients with breast cancer.Hsa-microRNA-101 suppresses migration and invasion by targeting Rac1 in thyroid cancer cells.MiR-204 inhibits human NSCLC metastasis through suppression of NUAK1.miRNome of inflammatory breast cancer.Cell-specific post-transcriptional regulation of γ-synuclein gene by micro-RNAs.A TrkB-STAT3-miR-204-5p regulatory circuitry controls proliferation and invasion of endometrial carcinoma cells MicroRNAs in pulmonary arterial hypertension.Discover the molecular biomarker associated with cell death and extracellular matrix module in ovarian cancer.rpS6 regulates blood-testis barrier dynamics through Arp3-mediated actin microfilament organization in rat sertoli cells. An in vitro study Low expression of microRNA-204 (miR-204) is associated with poor clinical outcome of acute myeloid leukemia (AML) patients.Identification of potential biomarkers to differentially diagnose solid pseudopapillary tumors and pancreatic malignancies via a gene regulatory network.The importance of the PI3K/AKT/MTOR pathway in the progression of ovarian cancer.Genome-wide identification of target genes for miR-204 and miR-211 identifies their proliferation stimulatory role in breast cancer cells Inhibition of FoxM1-Mediated DNA Repair by Imipramine Blue Suppresses Breast Cancer Growth and Metastasis Dual targeting of ANGPT1 and TGFBR2 genes by miR-204 controls angiogenesis in breast cancer.Suppression of choriocarcinoma invasion and metastasis following blockade of BDNF/TrkB signaling.The role and regulation of Rab40b-Tks5 complex during invadopodia formation and cancer cell invasion.miR-486-3p, miR-139-5p, and miR-21 as Biomarkers for the Detection of Oral Tongue Squamous Cell Carcinoma.The human BDNF gene: peripheral gene expression and protein levels as biomarkers for psychiatric disorders.Genomic alterations as mediators of miRNA dysregulation in ovarian cancer.Epigenetic targets for novel therapies of lung diseases.From microRNA target validation to therapy: lessons learned from studies on BDNF.MiRNA-based therapeutic intervention of cancer.MiR-204 silencing in intraepithelial to invasive cutaneous squamous cell carcinoma progression.MiR-204-5p/Six1 feedback loop promotes epithelial-mesenchymal transition in breast cancer.miR-204 is dysregulated in metastatic prostate cancer in vitro.Quantitative changes in the protein and miRNA cargo of plasma exosome-like vesicles after exposure to ionizing radiation.TRPM3 and miR-204 establish a regulatory circuit that controls oncogenic autophagy in clear cell renal cell carcinoma.Therapeutic Potentials of BDNF/TrkB in Breast Cancer; Current Status and Perspectives.Emerging Role of MicroRNAs in mTOR Signaling.MicroRNAs in gynecological cancers: Small molecules with big implications.Transformer 2β and miR-204 regulate apoptosis through competitive binding to 3' UTR of BCL2 mRNA.A validated microRNA profile with predictive potential in glioblastoma patients treated with bevacizumab.

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Genomic loss of tumor suppressor miRNA-204 promotes cancer cell migration and invasion by activating AKT/mTOR/Rac1 signaling and actin reorganization

http://www.wikidata.org/entity/Q34533814

description

2012 nî lūn-bûn

@nan

2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Genomic loss of tumor suppress ...... aling and actin reorganization

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Genomic loss of tumor suppress ...... aling and actin reorganization

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Genomic loss of tumor suppress ...... aling and actin reorganization

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type

label

Genomic loss of tumor suppress ...... aling and actin reorganization

@ast

Genomic loss of tumor suppress ...... aling and actin reorganization

@en

Genomic loss of tumor suppress ...... aling and actin reorganization

@nl

prefLabel

Genomic loss of tumor suppress ...... aling and actin reorganization

@ast

Genomic loss of tumor suppress ...... aling and actin reorganization

@en

Genomic loss of tumor suppress ...... aling and actin reorganization

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JOURNAL.PONE.0052397

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Genomic loss of tumor suppress ...... aling and actin reorganization

@en

P2093

Behyar Zoghi

http://www.w3.org/2001/XMLSchema#string

Gail Tomlinson

http://www.w3.org/2001/XMLSchema#string

Hima Bansal

http://www.w3.org/2001/XMLSchema#string

Hung-I Harry Chen

http://www.w3.org/2001/XMLSchema#string

Jason R Plyler

http://www.w3.org/2001/XMLSchema#string

Jeffrey Dome

http://www.w3.org/2001/XMLSchema#string

Jennifer Rebeles

http://www.w3.org/2001/XMLSchema#string

Kalyan C Buddavarapu

http://www.w3.org/2001/XMLSchema#string

Manjeet K Rao

http://www.w3.org/2001/XMLSchema#string

Peter Hornsby

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P2860

The Hallmarks of Cancer

Selective activation of Akt1 by mammalian target of rapamycin complex 2 regulates cancer cell migration, invasion, and metastasis

Akt/PKB regulates actin organization and cell motility via Girdin/APE

Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

Combinatorial microRNA target predictions

Mammalian microRNAs predominantly act to decrease target mRNA levels

Oncomirs - microRNAs with a role in cancer

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

MicroRNAs: genomics, biogenesis, mechanism, and function

TrkB binds and tyrosine-phosphorylates Tiam1, leading to activation of Rac1 and induction of changes in cellular morphology

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e52397

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scholarly article

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10.1371/JOURNAL.PONE.0052397

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12

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7

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Alexander Pertsemlidis

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2012-12-21T00:00:00Z

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234043861

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23285024

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3528651

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