Chromosome integrity at a double-strand break requires exonuclease 1 and MRX
about
Relative contribution of four nucleases, CtIP, Dna2, Exo1 and Mre11, to the initial step of DNA double-strand break repair by homologous recombination in both the chicken DT40 and human TK6 cell linesTel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand BreaksAnticheckpoint pathways at telomeres in yeast.Coincident resection at both ends of random, γ-induced double-strand breaks requires MRX (MRN), Sae2 (Ctp1), and Mre11-nucleaseDynamics of double strand breaks and chromosomal translocationsFunctional interplay between the 53BP1-ortholog Rad9 and the Mre11 complex regulates resection, end-tethering and repair of a double-strand break.Correct end use during end joining of multiple chromosomal double strand breaks is influenced by repair protein RAD50, DNA-dependent protein kinase DNA-PKcs, and transcription context.Recombinational repair of radiation-induced double-strand breaks occurs in the absence of extensive resection.The sister chromatid cohesion pathway suppresses multiple chromosome gain and chromosome amplification.Structurally distinct Mre11 domains mediate MRX functions in resection, end-tethering and DNA damage resistance.
P2860
Q28269335-92D792A5-D2E6-49E7-B648-3ED53B86A2F0Q28550291-D8D6623C-32DA-4FB1-8530-A6EC297B32C5Q34161536-A0F1C368-8B15-41C7-A0AF-EF49CA99A7B6Q34650076-CCAA8BFA-674E-4B84-865A-EED75856A4E8Q34894253-AD9ADF83-7E53-4A01-98F6-BB02693E5318Q35539921-6F3CDDFB-8AD0-46CE-AE24-49FAE3C1B8E1Q35604928-2B662EE8-B0BF-40B5-843E-B788D39C0B2BQ36532628-DCA4254E-54EB-4C74-B0C0-4CEC46A16D46Q37557416-21D63683-7E06-4907-AFCA-614DFAB678D2Q50113705-73E58F1B-9E95-4926-91AF-981C5248DD57
P2860
Chromosome integrity at a double-strand break requires exonuclease 1 and MRX
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Chromosome integrity at a double-strand break requires exonuclease 1 and MRX
@ast
Chromosome integrity at a double-strand break requires exonuclease 1 and MRX
@en
Chromosome integrity at a double-strand break requires exonuclease 1 and MRX
@nl
type
label
Chromosome integrity at a double-strand break requires exonuclease 1 and MRX
@ast
Chromosome integrity at a double-strand break requires exonuclease 1 and MRX
@en
Chromosome integrity at a double-strand break requires exonuclease 1 and MRX
@nl
prefLabel
Chromosome integrity at a double-strand break requires exonuclease 1 and MRX
@ast
Chromosome integrity at a double-strand break requires exonuclease 1 and MRX
@en
Chromosome integrity at a double-strand break requires exonuclease 1 and MRX
@nl
P2093
P2860
P1433
P1476
Chromosome integrity at a double-strand break requires exonuclease 1 and MRX
@en
P2093
Elaine Yeh
Jim Westmoreland
Kerry Bloom
Michael A Resnick
Wataru Nakai
P2860
P304
P356
10.1016/J.DNAREP.2010.10.004
P577
2010-11-05T00:00:00Z