Structural requirements for cub domain containing protein 1 (CDCP1) and Src dependent cell transformation
about
CDCP1 identifies a CD146 negative subset of marrow fibroblasts involved with cytokine production.Cell line and patient-derived xenograft models reveal elevated CDCP1 as a target in high-grade serous ovarian cancer.CUB domain-containing protein 1 and the epidermal growth factor receptor cooperate to induce cell detachment.CDCP1 cleavage is necessary for homodimerization-induced migration of triple-negative breast cancer.New crossroads for potential therapeutic intervention in cancer - intersections between CDCP1, EGFR family members and downstream signaling pathways.Antibody mediated CDCP1 degradation as mode of action for cancer targeted therapy.The PDGFRβ/ERK1/2 pathway regulates CDCP1 expression in triple-negative breast cancer.
P2860
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P2860
Structural requirements for cub domain containing protein 1 (CDCP1) and Src dependent cell transformation
description
2012 nî lūn-bûn
@nan
2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Structural requirements for cu ...... dependent cell transformation
@ast
Structural requirements for cu ...... dependent cell transformation
@en
Structural requirements for cub domain containing protein 1
@nl
type
label
Structural requirements for cu ...... dependent cell transformation
@ast
Structural requirements for cu ...... dependent cell transformation
@en
Structural requirements for cub domain containing protein 1
@nl
prefLabel
Structural requirements for cu ...... dependent cell transformation
@ast
Structural requirements for cu ...... dependent cell transformation
@en
Structural requirements for cub domain containing protein 1
@nl
P2093
P2860
P1433
P1476
Structural requirements for cu ...... dependent cell transformation
@en
P2093
Birgit Bossenmaier
Gerhard Niederfellner
Gwendlyn Kollmorgen
Reiner Lammers
P2860
P304
P356
10.1371/JOURNAL.PONE.0053050
P407
P577
2012-12-31T00:00:00Z