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The somatotrope as a metabolic sensor: deletion of leptin receptors causes obesity.

The somatotrope as a metabolic sensor: deletion of leptin receptors causes obesity.

http://www.wikidata.org/entity/Q34548913

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Developments in our understanding of the effects of growth hormone on white adipose tissue from mice: implications to the clinic.Selective deletion of leptin receptors in gonadotropes reveals activin and GnRH-binding sites as leptin targets in support of fertility Cellular and molecular specificity of pituitary gland physiology.Adipocyte versus pituitary leptin in the regulation of pituitary hormones: somatotropes develop normally in the absence of circulating leptin.The use of three-dimensional printing to produce in vitro slice chambers Energy homeostasis targets chromosomal reconfiguration of the human GH1 locus Cytochrome P450 1B1: An unexpected modulator of liver fatty acid homeostasis Giant mice reveal new roles for GH in regulating the adipose immune microenvironment.Sex Differences in Somatotrope Dependency on Leptin Receptors in Young Mice: Ablation of LEPR Causes Severe Growth Hormone Deficiency and Abdominal Obesity in Males.The intricate role of growth hormone in metabolism.Does the pituitary somatotrope play a primary role in regulating GH output in metabolic extremes?Ablation of leptin signaling to somatotropes: changes in metabolic factors that cause obesity Ghrelin restoration of function in vitro in somatotropes from male mice lacking the Janus kinase (JAK)-binding site of the leptin receptor.Adipocyte Versus Somatotrope Leptin: Regulation of Metabolic Functions in the Mouse.The GH/IGF-1 axis in obesity: pathophysiology and therapeutic considerations.Maternal obesity programs reduced leptin signaling in the pituitary and altered GH/IGF1 axis function leading to increased adiposity in adult sheep offspring.Adipokines (Leptin, Adiponectin, Resistin) Differentially Regulate All Hormonal Cell Types in Primary Anterior Pituitary Cell Cultures from Two Primate Species Delta-like protein 1 in the pituitary-adipose axis in the adult male mouse.A Sex-Dependent, Tropic Role for Leptin in the Somatotrope as a Regulator of POU1F1 and POU1F1-Dependent Hormones Leptin Regulation of Gonadotrope Gonadotropin-Releasing Hormone Receptors As a Metabolic Checkpoint and Gateway to Reproductive Competence.The Growth Hormone Receptor: Mechanism of Receptor Activation, Cell Signaling, and Physiological Aspects.

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P2860

The somatotrope as a metabolic sensor: deletion of leptin receptors causes obesity.

http://www.wikidata.org/entity/Q34548913

description

2010 nî lūn-bûn

@nan

2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

The somatotrope as a metabolic sensor: deletion of leptin receptors causes obesity.

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The somatotrope as a metabolic sensor: deletion of leptin receptors causes obesity.

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The somatotrope as a metabolic sensor: deletion of leptin receptors causes obesity.

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The somatotrope as a metabolic sensor: deletion of leptin receptors causes obesity.

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The somatotrope as a metabolic sensor: deletion of leptin receptors causes obesity.

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The somatotrope as a metabolic sensor: deletion of leptin receptors causes obesity.

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The somatotrope as a metabolic sensor: deletion of leptin receptors causes obesity.

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The somatotrope as a metabolic sensor: deletion of leptin receptors causes obesity.

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The somatotrope as a metabolic sensor: deletion of leptin receptors causes obesity.

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The somatotrope as a metabolic sensor: deletion of leptin receptors causes obesity

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Amanda Charlesworth

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Anessa Haney

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Christopher Crane

http://www.w3.org/2001/XMLSchema#string

Dana Gaddy

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Gwen V Childs

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Helen Benes

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Michael Cozart

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Mohsin Syed

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Nisreen Akel

http://www.w3.org/2001/XMLSchema#string

Noor Akhter

http://www.w3.org/2001/XMLSchema#string

P2860

Positional cloning of the mouse obese gene and its human homologue

A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men

Congenital leptin deficiency is associated with severe early-onset obesity in humans

Role of leptin in the neuroendocrine response to fasting

Regulation of growth hormone secretion by signals produced by the adipose tissue.

Neuroendocrine regulation and actions of leptin.

Effects of recombinant leptin therapy in a child with congenital leptin deficiency.

Fasting regulates hypothalamic neuropeptide Y, agouti-related peptide, and proopiomelanocortin in diabetic mice independent of changes in leptin or insulin.

Leptin and the pituitary.

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69-81

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scholarly article

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10.1210/EN.2010-0498

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1

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152

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Rhonda D Kineman

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2010-11-17T00:00:00Z

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47811781

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21084451

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