Mitochondrial telomerase protects cancer cells from nuclear DNA damage and apoptosis
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Cancer-Specific Telomerase Reverse Transcriptase (TERT) Promoter Mutations: Biological and Clinical ImplicationsTelomerase: The Devil InsideImplications of telomeres and telomerase in endometrial pathologyThe association between the TERT rs2736100 AC genotype and reduced risk of upper tract urothelial carcinomas in a Han Chinese populationRUG3 and ATM synergistically regulate the alternative splicing of mitochondrial nad2 and the DNA damage response in Arabidopsis thaliana.Crosstalk between apoptosis and autophagy: molecular mechanisms and therapeutic strategies in cancer.Telomere maintenance mechanisms in cancer: clinical implicationsEffects of mitochondrial translocation of telomerase on drug resistance in hepatocellular carcinoma cells.The role of telomerase protein TERT in Alzheimer's disease and in tau-related pathology in vitro.Impact of mitochondrial telomerase over-expression on drug resistance of hepatocellular carcinoma.Telomerase activity and telomere length in Daphnia.The DNA methylation inhibitor induces telomere dysfunction and apoptosis of leukemia cells that is attenuated by telomerase over-expression.Saccharomyces cerevisiae as a model for the study of extranuclear functions of mammalian telomeraseFucoidan Induces ROS-Dependent Apoptosis in 5637 Human Bladder Cancer Cells by Downregulating Telomerase Activity via Inactivation of the PI3K/Akt Signaling Pathway.Bortezomib-mediated down-regulation of telomerase and disruption of telomere homeostasis contributes to apoptosis of malignant cells.Telomerase Activity is Downregulated Early During Human Brain Development.Cancer prevention and therapy through the modulation of the tumor microenvironment.The role of telomeres and telomerase reverse transcriptase isoforms in pluripotency induction and maintenanceTERT rs2736100 genotypes are associated with differential risk of myeloproliferative neoplasms in Swedish and Chinese male patient populations.The emergence of the mitochondrial genome as a partial regulator of nuclear function is providing new insights into the genetic mechanisms underlying age-related complex disease.From radioresistance to radiosensitivity: In vitro evolution of L5178Y lymphoma.Genetic and epigenetic trends in telomere research: a novel way in immunoepigenetics.Berberine Regulated Lipid Metabolism in the Presence of C75, Compound C, and TOFA in Breast Cancer Cell Line MCF-7.Impaired telomerase activity hinders proliferation and in vitro transformation of Penaeus monodon lymphoid cells.Molecular mechanisms of mTOR regulation by stressQuantitative assessment of telomerase components in cancer cell lines.Mitochondrial redox system, dynamics, and dysfunction in lung inflammaging and COPD.Decreased mTOR signalling reduces mitochondrial ROS in brain via accumulation of the telomerase protein TERT within mitochondria.Telomerase and drug resistance in cancer.Telomerase reverse transcriptase promotes chemoresistance by suppressing cisplatin-dependent apoptosis in osteosarcoma cells.Systematic analysis of human telomeric dysfunction using inducible telosome/shelterin CRISPR/Cas9 knockout cellsZebrafish in oncology.Telomerase activity-independent function of telomerase reverse transcriptase is involved in acrylamide-induced neuron damage.Cell Biology of the Mitochondrion.Epigenetic silencing of miR-296 and miR-512 ensures hTERT dependent apoptosis protection and telomere maintenance in basal-type breast cancer cells.Acquired TERT promoter mutations stimulate TERT transcription in mantle cell lymphoma.Protein encoded in human telomerase RNA is involved in cell protective pathways
P2860
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P2860
Mitochondrial telomerase protects cancer cells from nuclear DNA damage and apoptosis
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2013 nî lūn-bûn
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2013 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Mitochondrial telomerase protects cancer cells from nuclear DNA damage and apoptosis
@ast
Mitochondrial telomerase protects cancer cells from nuclear DNA damage and apoptosis
@en
Mitochondrial telomerase protects cancer cells from nuclear DNA damage and apoptosis
@nl
type
label
Mitochondrial telomerase protects cancer cells from nuclear DNA damage and apoptosis
@ast
Mitochondrial telomerase protects cancer cells from nuclear DNA damage and apoptosis
@en
Mitochondrial telomerase protects cancer cells from nuclear DNA damage and apoptosis
@nl
prefLabel
Mitochondrial telomerase protects cancer cells from nuclear DNA damage and apoptosis
@ast
Mitochondrial telomerase protects cancer cells from nuclear DNA damage and apoptosis
@en
Mitochondrial telomerase protects cancer cells from nuclear DNA damage and apoptosis
@nl
P2093
P2860
P50
P1433
P1476
Mitochondrial telomerase protects cancer cells from nuclear DNA damage and apoptosis
@en
P2093
Chatchawan Singhapol
Deepali Pal
Mahendar Porika
P2860
P304
P356
10.1371/JOURNAL.PONE.0052989
P407
P577
2013-01-09T00:00:00Z