Rapid emergence of protease inhibitor resistance in hepatitis C virus.
about
Targeted DNA mutagenesis for the cure of chronic viral infectionsHepatitis C virus protease inhibitor-resistance mutations: our experience and reviewTreatment of chronic hepatitis C with direct-acting antivirals: The role of resistanceHepatitis C genotype 4: The past, present, and futureProfile of paritaprevir/ritonavir/ombitasvir plus dasabuvir in the treatment of chronic hepatitis C virus genotype 1 infectionHCV Kinetic Models and Their Implications in Drug DevelopmentViral kinetic modeling: state of the artEvolutionary rescue: linking theory for conservation and medicineModelling hepatitis C therapy--predicting effects of treatmentFuture classes of hepatitis C virus therapeutic agentsPredicting resistance mutations using protein design algorithmsThe Molecular Basis of Drug Resistance against Hepatitis C Virus NS3/4A Protease InhibitorsThe FDA-approved drug sofosbuvir inhibits Zika virus infectionA novel small molecule inhibitor of hepatitis C virus entryMathematical model of viral kinetics in vitro estimates the number of E2-CD81 complexes necessary for hepatitis C virus entryCellular growth kinetics distinguish a cyclophilin inhibitor from an HSP90 inhibitor as a selective inhibitor of hepatitis C virusProbing of exosites leads to novel inhibitor scaffolds of HCV NS3/4A proteinaseHCV genotypes are differently prone to the development of resistance to linear and macrocyclic protease inhibitorsSpontaneous clearance of viral infections by mesoscopic fluctuationsDeep sequencing analysis of HCV NS3 resistance-associated variants and mutation linkage in liver transplant recipientsA novel compound from the mushroom Cryptoporus volvatus inhibits porcine reproductive and respiratory syndrome virus (PRRSV) in vitroA quantitative high-resolution genetic profile rapidly identifies sequence determinants of hepatitis C viral fitness and drug sensitivityHepatitis C virus cell-cell transmission and resistance to direct-acting antiviral agentsIntact dendritic cell pathogen-recognition receptor functions associate with chronic hepatitis C treatment-induced viral clearanceA new stochastic model for subgenomic hepatitis C virus replication considers drug resistant mutantsA hepatitis C virus infection model with time-varying drug effectiveness: solution and analysisModeling viral evolutionary dynamics after telaprevir-based treatmentRational Design and Adaptive Management of Combination Therapies for Hepatitis C Virus InfectionAnalysis of Dengue Virus Genetic Diversity during Human and Mosquito Infection Reveals Genetic ConstraintsMultiple Introduction and Naturally Occuring Drug Resistance of HCV among HIV-Infected Intravenous Drug Users in Yunnan: An Origin of China's HIV/HCV EpidemicsHepatitis C viral evolution in genotype 1 treatment-naïve and treatment-experienced patients receiving telaprevir-based therapy in clinical trialsNatural HCV variants with increased replicative fitness due to NS3 helicase mutations in the C-terminal helix α18Treatment of hepatitis C with an interferon-based lead-in phase: a perspective from mathematical modellingReplication vesicles are load- and choke-points in the hepatitis C virus lifecycle.The hepatitis C virus NS5A inhibitor daclatasvir has a dual mode of action and leads to a new virus half-life estimateRibavirin-induced anemia in hepatitis C virus patients undergoing combination therapy.Small molecules targeting hepatitis C virus-encoded NS5A cause subcellular redistribution of their target: insights into compound modes of action.A new model to produce infectious hepatitis C virus without the replication requirement.Using pharmacokinetic and viral kinetic modeling to estimate the antiviral effectiveness of telaprevir, boceprevir, and pegylated interferon during triple therapy in treatment-experienced hepatitis C virus-infected cirrhotic patientsA viral dynamic model for treatment regimens with direct-acting antivirals for chronic hepatitis C infection.
P2860
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P2860
Rapid emergence of protease inhibitor resistance in hepatitis C virus.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Rapid emergence of protease inhibitor resistance in hepatitis C virus.
@ast
Rapid emergence of protease inhibitor resistance in hepatitis C virus.
@en
Rapid emergence of protease inhibitor resistance in hepatitis C virus.
@nl
type
label
Rapid emergence of protease inhibitor resistance in hepatitis C virus.
@ast
Rapid emergence of protease inhibitor resistance in hepatitis C virus.
@en
Rapid emergence of protease inhibitor resistance in hepatitis C virus.
@nl
prefLabel
Rapid emergence of protease inhibitor resistance in hepatitis C virus.
@ast
Rapid emergence of protease inhibitor resistance in hepatitis C virus.
@en
Rapid emergence of protease inhibitor resistance in hepatitis C virus.
@nl
P2860
P1476
Rapid emergence of protease inhibitor resistance in hepatitis C virus.
@en
P2093
Harel Dahari
Libin Rong
P2860
P304
P356
10.1126/SCITRANSLMED.3000544
P407
P577
2010-05-01T00:00:00Z