The nitric oxide prodrug JS-K is effective against non-small-cell lung cancer cells in vitro and in vivo: involvement of reactive oxygen species.
about
Fifty years of diazeniumdiolate research. From laboratory curiosity to broad-spectrum biomedical advancesPeroxiredoxin 1 - an antioxidant enzyme in cancerCross-linking protein glutathionylation mediated by O2-arylated bis-diazeniumdiolate "Double JS-K".Synthesis and characterization of a multi-arm poly(acrylic acid) star polymer for application in sustained delivery of cisplatin and a nitric oxide prodrug.Cellular distribution studies of the nitric oxide-generating antineoplastic prodrug O(2) -(2,4-dinitrophenyl)1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate formulated in Pluronic P123 micelles.JS-K promotes apoptosis by inducing ROS production in human prostate cancer cellsEffect of a Pluronic(®) P123 formulation on the nitric oxide-generating drug JS-K.JS-K, a glutathione S-transferase-activated nitric oxide donor with antineoplastic activity in malignant gliomas.A reactive oxygen species activation mechanism contributes to JS-K-induced apoptosis in human bladder cancer cells.Activation of the c-Jun N-terminal kinase/activating transcription factor 3 (ATF3) pathway characterizes effective arylated diazeniumdiolate-based nitric oxide-releasing anticancer prodrugs.Nitrosothiol-Trapping-Based Proteomic Analysis of S-Nitrosylation in Human Lung Carcinoma CellsStructural modifications modulate stability of glutathione-activated arylated diazeniumdiolate prodrugs.Bioinformatics analysis reveals biophysical and evolutionary insights into the 3-nitrotyrosine post-translational modification in the human proteomeN-(2-Hydroxypropyl)methacrylamide Copolymer-Drug Conjugates for Combination Chemotherapy of Acute Myeloid LeukemiaThiol Modification By Pharmacologically Active Agents of the Diazeniumdiolate ClassNitric oxide-releasing prodrug triggers cancer cell death through deregulation of cellular redox balance.Decoding nitric oxide release rates of amine-based diazeniumdiolates.Nitric oxide (NO) releasing poly ADP-ribose polymerase 1 (PARP-1) inhibitors targeted to glutathione S-transferase P1-overexpressing cancer cells.Oxidative stress in oncohematologic diseases: an update.JS-K, a GST-activated nitric oxide donor prodrug, enhances chemo-sensitivity in renal carcinoma cells and prevents cardiac myocytes toxicity induced by Doxorubicin.CYP3A5 mediates bioactivation and cytotoxicity of tetrandrine.Effect of hesperidin on mice bearing Ehrlich solid carcinoma maintained on doxorubicin.Evaluation of nestin in lung adenocarcinoma: relation to VEGF and Bcl-2.The nitric oxide donor JS-K sensitizes U87 glioma cells to repetitive irradiation.Glutathione S -transferase π: a potential role in antitumor therapy
P2860
Q27015464-3E2749A2-F776-4BEE-9664-C4A69099C2EFQ28070359-A4757FF5-63C3-463A-9246-84A918981C9BQ30422929-9B599800-BE3B-4044-BB1A-07D66CA731FAQ31019887-28369314-2440-4E33-8DE3-47849F52BF90Q33565776-2DB4DD3D-F837-47E0-AE7C-44A774E25CB6Q33598148-C8DF8EE3-E3F1-487F-81E7-C023224C4771Q35175551-8A2C3CA2-ECDF-4E9F-9EAA-3423DBB2636EQ35658977-CF3B1B2C-23B8-49D3-9852-6A4BB2231A17Q36149908-D17E1022-CE64-4AB1-AA27-BA7936E5FC76Q36175366-1849F79B-D1DF-4408-ACF2-B80FDF399647Q36247835-27C08830-F766-4E22-9876-A5B10A33CECBQ36664227-2C7C9DDF-CF61-4DA5-9019-52D9180E7437Q36702406-5C41864A-169A-4B39-B5F8-90D64D5A7CC7Q36722841-C135FD33-41CE-498E-88D2-1592EB828905Q36754617-F88D0067-6EB0-437E-A998-811321B30DF8Q37133470-51CA22F5-E013-4DF7-A71F-BF0D90B7E365Q37149496-9A6DF065-C74A-41EE-99F0-87D12C7514DBQ37697400-86894985-F5C8-49C8-AD83-2337343C831BQ38115588-A3D4EA43-0EFD-4AEB-88C6-2EECDA615B5CQ38700491-D4021BCA-EEFF-4FAD-B676-83BA6FAACF16Q38841240-CE599B83-941D-4753-B7AB-945E8350598DQ46350707-10AB74A0-6D50-4C36-8815-A3DA1BBF2D97Q46495496-D3183B90-615D-403D-A2CF-A53CF498641DQ48222651-EFCEFE1A-6712-4106-9D4E-DE43545C1812Q58694500-05BC3FBE-6881-4E14-AA5E-C8BC8A791489
P2860
The nitric oxide prodrug JS-K is effective against non-small-cell lung cancer cells in vitro and in vivo: involvement of reactive oxygen species.
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The nitric oxide prodrug JS-K ...... nt of reactive oxygen species.
@ast
The nitric oxide prodrug JS-K ...... nt of reactive oxygen species.
@en
The nitric oxide prodrug JS-K ...... nt of reactive oxygen species.
@nl
type
label
The nitric oxide prodrug JS-K ...... nt of reactive oxygen species.
@ast
The nitric oxide prodrug JS-K ...... nt of reactive oxygen species.
@en
The nitric oxide prodrug JS-K ...... nt of reactive oxygen species.
@nl
prefLabel
The nitric oxide prodrug JS-K ...... nt of reactive oxygen species.
@ast
The nitric oxide prodrug JS-K ...... nt of reactive oxygen species.
@en
The nitric oxide prodrug JS-K ...... nt of reactive oxygen species.
@nl
P2093
P2860
P356
P1476
The nitric oxide prodrug JS-K ...... nt of reactive oxygen species.
@en
P2093
Anna E Maciag
Harinath Chakrapani
Joseph E Saavedra
Ken M Kosak
Larry K Keefer
Lucy M Anderson
Nicole L Morris
Paul J Shami
Ryan J Holland
P2860
P304
P356
10.1124/JPET.110.174904
P407
P577
2010-10-20T00:00:00Z