Glycogen synthase kinase 3: an emerging therapeutic target.
about
GSK-3 Inhibitors: Preclinical and Clinical Focus on CNSGlycogen synthase kinase 3: more than a namesakeWNT7a induces E-cadherin in lung cancer cellsGSK-3: tricks of the trade for a multi-tasking kinaseGlycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeuticsChronic over-nutrition and dysregulation of GSK3 in diseasesInhibition of glioblastoma growth by the thiadiazolidinone compound TDZD-8Possible role of the glycogen synthase kinase-3 signaling pathway in trimethyltin-induced hippocampal neurodegeneration in miceNFAT/Fas signaling mediates the neuronal apoptosis and motor side effects of GSK-3 inhibition in a mouse model of lithium therapyInsulin signaling regulates a functional interaction between adenomatous polyposis coli and cytoplasmic dynein.Akt: A Therapeutic Target in Hepatic Ischemia-Reperfusion Injury.Identification of a glycogen synthase kinase-3β inhibitor that attenuates hyperactivity in CLOCK mutant mice.Control of neuronal ion channel function by glycogen synthase kinase-3: new prospective for an old kinase.Glycogen synthase kinase 3 alpha and 3 beta have distinct functions during cardiogenesis of zebrafish embryo.Silencing glycogen synthase kinase-3beta inhibits acetaminophen hepatotoxicity and attenuates JNK activation and loss of glutamate cysteine ligase and myeloid cell leukemia sequence 1.Tissue-specific analysis of glycogen synthase kinase-3α (GSK-3α) in glucose metabolism: effect of strain variation.Thyroid states regulate subcellular glucose phosphorylation activity in male mice.Dynamin I phosphorylation by GSK3 controls activity-dependent bulk endocytosis of synaptic vesicles.Different susceptibility to neurodegeneration of dorsal and ventral hippocampal dentate gyrus: a study with transgenic mice overexpressing GSK3β.Phosphorylation of tau protein over time in rats subjected to transient brain ischemia.Phosphorylation of LCRMP-1 by GSK3β promotes filopoda formation, migration and invasion abilities in lung cancer cellsMolecular basis of lithium action: integration of lithium-responsive signaling and gene expression networks.Glycogen synthase kinase 3β (GSK3β) modulates antiviral activity of zinc-finger antiviral protein (ZAP).Hepatitis C virus E2 protein involve in insulin resistance through an impairment of Akt/PKB and GSK3β signaling in hepatocytes.Physiological and pathological changes in glucose regulate brain Akt and glycogen synthase kinase-3.Cdc42-mediated inhibition of GSK-3β improves angio-architecture and lumen formation during VEGF-driven pathological angiogenesis.ON01210.Na (Ex-RAD®) mitigates radiation damage through activation of the AKT pathway.CG0009, a novel glycogen synthase kinase 3 inhibitor, induces cell death through cyclin D1 depletion in breast cancer cells.Distinct molecular regulation of glycogen synthase kinase-3alpha isozyme controlled by its N-terminal region: functional role in calcium/calpain signaling.Mitochondrial hexokinase II promotes neuronal survival and acts downstream of glycogen synthase kinase-3.The role of glycogen synthase kinase-3 in insulin resistance and type 2 diabetes.Glycogen-synthase kinase-3beta is decreased in peripheral blood mononuclear cells of patients with mild cognitive impairmentObesity, insulin resistance, and Alzheimer's disease.Citrus flavonoids luteolin, apigenin, and quercetin inhibit glycogen synthase kinase-3β enzymatic activity by lowering the interaction energy within the binding cavity.Deregulation of the phosphatidylinositol-3 kinase signaling cascade is associated with neurodegeneration in Npc1-/- mouse brain.The paradoxical pro- and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways.In vivo regulation of GSK3 phosphorylation by cholinergic and NMDA receptors.Challenges and opportunities with glycogen synthase kinase-3 inhibitors for insulin resistance and Type 2 diabetes treatment.Novel concepts in insulin regulation of hepatic gluconeogenesis.Neuroprotective actions of ghrelin and growth hormone secretagogues.
P2860
Q21129334-208BB998-E1CF-4D27-87CA-DC0E3762E396Q24315635-29FA84AD-33D4-4272-B06A-7BC2A006E6E6Q24317695-03D3C893-92C5-44F8-ACBF-B94CC2235B9CQ24624069-82DBF8D6-80BE-401A-974C-192BCD1115A9Q24685475-105562CF-02ED-4286-B9BA-87DE264B5FE2Q26738964-E1BF1A4A-9563-45B3-B804-1A6A4288671EQ28476019-388D3F1F-4350-49BC-B76A-3C7201DE3C3DQ28535092-C6B4D891-8FA1-4141-B4F5-55F0C8FA63EDQ28586033-584B9A01-2F56-4E27-AA74-6EA2B26C07F3Q28910200-DB5E124E-0CD7-4DDA-941C-3B5A5CCA5E8EQ30248771-EF7DBB65-5CF2-49AB-B0FC-A1D0F9492746Q30464459-68330CE9-860F-4AA6-9193-2F1B54DAADE2Q30465622-B108A972-F567-4C9F-92C8-D335D8CD4492Q33293406-6ECECDBD-E2BE-4E47-9CC1-424CCD7BC310Q33707120-0F0CBE56-3C66-44D2-9D0C-D395B1BC459FQ33799189-E2CCCBE0-D3FF-47F2-934F-F118D44791C2Q33904219-FCE374EA-58B5-4A61-87FE-653C9747B04FQ33948657-13B9588D-9BEF-40F5-9DBA-3F22AB1DC5ECQ34071884-EFB84058-22E9-4195-B5FF-071CC1C30E88Q34095784-4EAA9383-3B91-4357-9332-C77F55A8C1D2Q34171261-DDDE5528-F079-4FC6-A0B0-C0DC4FF0661AQ34180376-AE05DE3E-021A-4C33-ACF7-4065BBE7128CQ34238255-84DFDA99-B125-48D7-8CD3-71541576383AQ34312988-ADC625FE-54D2-44C2-A412-C1172E5489CDQ34338701-3711ECAD-CC13-43B2-A778-966FD25455E1Q34491380-F668E798-B163-4A12-A4C9-6ACAE1CFC26CQ34625756-616E70BF-D4BF-43D1-8B80-F2AD3BD53373Q34658396-D0D565E9-AA4E-4F75-B489-BFC60BAA4D67Q34787299-69A8CCBA-B171-4C3E-8159-32FA4353D638Q34888702-F7334B06-1F0E-4D0F-AEF6-BE84AFBB1E94Q34974764-DE7FFF9E-1E31-493F-8484-44C59F6DBE37Q35028865-F368D75C-A279-4472-9AF6-B7B71F66E0A2Q35041925-20703098-D5D3-464F-BB1E-079E7B59448BQ35070396-1AA81421-797D-4814-ADDA-42466889C80CQ35085261-2B93148A-4CAB-4B77-B560-60295B2F157AQ35103813-BDADC501-9235-465D-A675-6C8CBFB5A502Q35103820-765DC223-CC4D-4FBE-8E46-77B458650858Q35207622-ED38220F-B7C1-4176-B7F0-C8DC16BBF929Q35213690-0CAC7144-6425-4176-8AE7-8F0BF565614FQ35237410-49AA461D-F525-496B-9625-F00951E1E43E
P2860
Glycogen synthase kinase 3: an emerging therapeutic target.
description
2002 nî lūn-bûn
@nan
2002 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մարտին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Glycogen synthase kinase 3: an emerging therapeutic target.
@ast
Glycogen synthase kinase 3: an emerging therapeutic target.
@en
Glycogen synthase kinase 3: an emerging therapeutic target.
@nl
type
label
Glycogen synthase kinase 3: an emerging therapeutic target.
@ast
Glycogen synthase kinase 3: an emerging therapeutic target.
@en
Glycogen synthase kinase 3: an emerging therapeutic target.
@nl
prefLabel
Glycogen synthase kinase 3: an emerging therapeutic target.
@ast
Glycogen synthase kinase 3: an emerging therapeutic target.
@en
Glycogen synthase kinase 3: an emerging therapeutic target.
@nl
P1476
Glycogen synthase kinase 3: an emerging therapeutic target.
@en
P304
P356
10.1016/S1471-4914(01)02266-3
P577
2002-03-01T00:00:00Z