Microglia mediate the clearance of soluble Abeta through fluid phase macropinocytosis.
about
Apolipoproteins E and J interfere with amyloid-beta uptake by primary human astrocytes and microglia in vitroHuman APOE genotype affects intraneuronal Aβ1-42 accumulation in a lentiviral gene transfer modelMechanisms of Aβ Clearance and Degradation by Glial CellsTDP-43: a new player on the AD field?The low-density lipoprotein receptor-related protein 1 and amyloid-β clearance in Alzheimer's diseaseTargeting microglial K(ATP) channels to treat neurodegenerative diseases: a mitochondrial issueApolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer diseaseFrom development to dysfunction: microglia and the complement cascade in CNS homeostasisInteraction between therapeutic interventions for Alzheimer's disease and physiological Aβ clearance mechanismsInnate immunity in Alzheimer's disease: a complex affairFunctional impairment of microglia coincides with Beta-amyloid deposition in mice with Alzheimer-like pathologyDisruption of arterial perivascular drainage of amyloid-β from the brains of mice expressing the human APOE ε4 alleleCCL2 accelerates microglia-mediated Abeta oligomer formation and progression of neurocognitive dysfunctionThe yin and yang of microgliaThe pathogenic implication of abnormal interaction between apolipoprotein E isoforms, amyloid-beta peptides, and sulfatides in Alzheimer's diseaseThe ubiquitin proteasome system in glia and its role in neurodegenerative diseasesSingle-walled carbon nanotubes alleviate autophagic/lysosomal defects in primary glia from a mouse model of Alzheimer's diseaseAmyloid-β-induced astrocytic phagocytosis is mediated by CD36, CD47 and RAGEHeparan sulphate proteoglycan and the low-density lipoprotein receptor-related protein 1 constitute major pathways for neuronal amyloid-beta uptake.Neuronal clearance of amyloid-β by endocytic receptor LRP1.Low-density lipoprotein receptor represents an apolipoprotein E-independent pathway of Aβ uptake and degradation by astrocytesPhagocytic clearance in neurodegeneration.Mechanisms of U87 astrocytoma cell uptake and trafficking of monomeric versus protofibril Alzheimer's disease amyloid-β proteinsMicroglia activated with the toll-like receptor 9 ligand CpG attenuate oligomeric amyloid {beta} neurotoxicity in in vitro and in vivo models of Alzheimer's disease.Attenuating astrocyte activation accelerates plaque pathogenesis in APP/PS1 mice.Arf6 controls beta-amyloid production by regulating macropinocytosis of the Amyloid Precursor Protein to lysosomesEfavirenz promotes β-secretase expression and increased Aβ1-40,42 via oxidative stress and reduced microglial phagocytosis: implications for HIV associated neurocognitive disorders (HAND).Inflammation, microglia, and Alzheimer's disease.Viewing ageing eyes: diverse sites of amyloid Beta accumulation in the ageing mouse retina and the up-regulation of macrophages.Viable mouse gene ablations that robustly alter brain Aβ levels are rare.Robust uptake of magnetic nanoparticles (MNPs) by central nervous system (CNS) microglia: implications for particle uptake in mixed neural cell populationsEnhancing astrocytic lysosome biogenesis facilitates Aβ clearance and attenuates amyloid plaque pathogenesisMicroglia activation and anti-inflammatory regulation in Alzheimer's diseaseSuppressed accumulation of cerebral amyloid {beta} peptides in aged transgenic Alzheimer's disease mice by transplantation with wild-type or prostaglandin E2 receptor subtype 2-null bone marrowAging reduces glial uptake and promotes extracellular accumulation of Aβ from a lentiviral vector.Glycogen synthase kinase-3 and p38 MAPK are required for opioid-induced microglia apoptosisDevelopment of non-viral vehicles for targeted gene transfer into microglia via the integrin receptor CD11b.Inhibiting ACAT1/SOAT1 in microglia stimulates autophagy-mediated lysosomal proteolysis and increases Aβ1-42 clearanceSUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease.Macrophage Migration Inhibitory Factor is subjected to glucose modification and oxidation in Alzheimer's Disease.
P2860
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P2860
Microglia mediate the clearance of soluble Abeta through fluid phase macropinocytosis.
description
2009 nî lūn-bûn
@nan
2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Microglia mediate the clearance of soluble Abeta through fluid phase macropinocytosis.
@ast
Microglia mediate the clearance of soluble Abeta through fluid phase macropinocytosis.
@en
Microglia mediate the clearance of soluble Abeta through fluid phase macropinocytosis.
@nl
type
label
Microglia mediate the clearance of soluble Abeta through fluid phase macropinocytosis.
@ast
Microglia mediate the clearance of soluble Abeta through fluid phase macropinocytosis.
@en
Microglia mediate the clearance of soluble Abeta through fluid phase macropinocytosis.
@nl
prefLabel
Microglia mediate the clearance of soluble Abeta through fluid phase macropinocytosis.
@ast
Microglia mediate the clearance of soluble Abeta through fluid phase macropinocytosis.
@en
Microglia mediate the clearance of soluble Abeta through fluid phase macropinocytosis.
@nl
P2093
P2860
P1476
Microglia mediate the clearance of soluble Abeta through fluid phase macropinocytosis.
@en
P2093
C Y Daniel Lee
Gary E Landreth
Jessica Koenigsknecht-Talboo
Qingguang Jiang
Shweta Mandrekar
P2860
P304
P356
10.1523/JNEUROSCI.5572-08.2009
P407
P577
2009-04-01T00:00:00Z