Mitochondrial hexokinases, novel mediators of the antiapoptotic effects of growth factors and Akt.
about
Is there a role for carbohydrate restriction in the treatment and prevention of cancer?SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growthHexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channelsProtein kinases and phosphatases in the control of cell fateHexokinase-2 bound to mitochondria: cancer's stygian link to the "Warburg Effect" and a pivotal target for effective therapyAnalyses of resected human brain metastases of breast cancer reveal the association between up-regulation of hexokinase 2 and poor prognosisGlycogen synthase kinase-3 inhibition induces glioma cell death through c-MYC, nuclear factor-kappaB, and glucose regulationAKT/PKB signaling: navigating downstreamInsights into the Regulatory Role of Non-coding RNAs in Cancer MetabolismEnergy metabolic dysfunction as a carcinogenic factor in cancer cellsMetabolomics in rheumatic diseases: desperately seeking biomarkersDysregulated metabolism contributes to oncogenesisReview of aerobic glycolysis and its key enzymes - new targets for lung cancer therapyReprogramming of glucose metabolism in hepatocellular carcinoma: Progress and prospectsRegulation of succinate-ubiquinone reductase and fumarate reductase activities in human complex II by phosphorylation of its flavoprotein subunitLong-term supplementation with a cystine-based antioxidant delays loss of muscle mass in agingOxidant Mechanisms in Renal Injury and DiseaseHexokinase-II positively regulates glucose starvation-induced autophagy through TORC1 inhibitionAssessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge aheadQuantitative proteomics reveals cellular targets of celastrolCardiac-specific hexokinase 2 overexpression attenuates hypertrophy by increasing pentose phosphate pathway fluxThe role of Akt/protein kinase B subtypes in retinal ischemic preconditioningMyotonic dystrophy protein kinase (DMPK) prevents ROS-induced cell death by assembling a hexokinase II-Src complex on the mitochondrial surfaceVisualizing sweetness: increasingly diverse applications for fluorescent-tagged glucose bioprobes and their recent structural modificationsTubulin binding blocks mitochondrial voltage-dependent anion channel and regulates respirationHexokinase II-derived cell-penetrating peptide targets mitochondria and triggers apoptosis in cancer cellsIs Akt the "Warburg kinase"?-Akt-energy metabolism interactions and oncogenesis.Tumor suppressor p53 and estrogen receptors in nuclear-mitochondrial communication.Testosterone supplementation reverses sarcopenia in aging through regulation of myostatin, c-Jun NH2-terminal kinase, Notch, and Akt signaling pathways.Activation of mitochondrial ERK protects cancer cells from death through inhibition of the permeability transitionAkt and c-Myc differentially activate cellular metabolic programs and prime cells to bioenergetic inhibition.Mfn2 is critical for brown adipose tissue thermogenic functionLow dose of 2-deoxy-D-glucose kills acute lymphoblastic leukemia cells and reverses glucocorticoid resistance via N-linked glycosylation inhibition under normoxia.The miR-125a/HK2 axis regulates cancer cell energy metabolism reprogramming in hepatocellular carcinomaMitochondrial integrity: preservation through Akt/Pim-1 kinase signaling in the cardiomyocyteSimultaneous stimulation of glycolysis and gluconeogenesis by feeding in the anterior intestine of the omnivorous GIFT tilapia, Oreochromis niloticus.Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy?Quantitative changes in the mitochondrial proteome from subjects with mild cognitive impairment, early stage, and late stage Alzheimer's disease.Renal cortical hexokinase and pentose phosphate pathway activation through the EGFR/Akt signaling pathway in endotoxin-induced acute kidney injury.A mutation in an alternative untranslated exon of hexokinase 1 associated with hereditary motor and sensory neuropathy -- Russe (HMSNR).
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P2860
Mitochondrial hexokinases, novel mediators of the antiapoptotic effects of growth factors and Akt.
description
2006 nî lūn-bûn
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2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
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2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
name
Mitochondrial hexokinases, nov ...... cts of growth factors and Akt.
@ast
Mitochondrial hexokinases, nov ...... cts of growth factors and Akt.
@en
Mitochondrial hexokinases, nov ...... cts of growth factors and Akt.
@nl
type
label
Mitochondrial hexokinases, nov ...... cts of growth factors and Akt.
@ast
Mitochondrial hexokinases, nov ...... cts of growth factors and Akt.
@en
Mitochondrial hexokinases, nov ...... cts of growth factors and Akt.
@nl
prefLabel
Mitochondrial hexokinases, nov ...... cts of growth factors and Akt.
@ast
Mitochondrial hexokinases, nov ...... cts of growth factors and Akt.
@en
Mitochondrial hexokinases, nov ...... cts of growth factors and Akt.
@nl
P356
P1433
P1476
Mitochondrial hexokinases, nov ...... cts of growth factors and Akt.
@en
P2888
P304
P356
10.1038/SJ.ONC.1209595
P407
P577
2006-08-01T00:00:00Z
P5875
P6179
1038088299