Microbicidal/cytotoxic proteins of neutrophils are deficient in two disorders: Chediak-Higashi syndrome and "specific" granule deficiency. - Wikidata - wikimedia - TriplyDB

Microbicidal/cytotoxic proteins of neutrophils are deficient in two disorders: Chediak-Higashi syndrome and "specific" granule deficiency.

Microbicidal/cytotoxic proteins of neutrophils are deficient in two disorders: Chediak-Higashi syndrome and "specific" granule deficiency.

http://www.wikidata.org/entity/Q34555280

about

Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity Neutrophil-specific granule deficiency results from a novel mutation with loss of function of the transcription factor CCAAT/enhancer binding protein epsilon Congenital defects in neutrophil dynamics Interactions between neutrophil-derived antimicrobial peptides and airway epithelial cells Resistance to host antimicrobial peptides is necessary for Salmonella virulence Manual annotation and analysis of the defensin gene cluster in the C57BL/6J mouse reference genome.Comparative genomics and host resistance against infectious diseases Enhancement of neonatal innate defense: effects of adding an N-terminal recombinant fragment of bactericidal/permeability-increasing protein on growth and tumor necrosis factor-inducing activity of gram-negative bacteria tested in neonatal cord bloo Animal antimicrobial peptides: an overview.Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases.In vitro killing of oral Capnocytophaga by granule fractions of human neutrophils is associated with cathepsin G activity.Antibiotic proteins of human neutrophils.Host defence peptides: antimicrobial and immunomodulatory activity and potential applications for tackling antibiotic-resistant infections.Antimicrobial peptides: properties and applicability.Selective defect in myeloid cell lactoferrin gene expression in neutrophil specific granule deficiency Monocyte-chemotactic activity of defensins from human neutrophils.Skin fibroblasts from individuals with Chediak-Higashi Syndrome (CHS) exhibit hyposensitive immunogenic response.In vitro studies on the antimicrobial peptide human beta-defensin 9 (HBD9): signalling pathways and pathogen-related response (an American Ophthalmological Society thesis).In vitro sensitivity of oral, gram-negative, facultative bacteria to the bactericidal activity of human neutrophil defensins.Human α-defensin expression is not dependent on CCAAT/enhancer binding protein-ε in a murine model.Infections in patients with inherited defects in phagocytic function.The role of defensins in lung biology and therapy.The antimicrobial propeptide hCAP-18 plasma levels in neutropenia of various aetiologies: a prospective study.Psoriatic scales: a promising source for the isolation of human skin-derived antimicrobial proteins.The PhoQ-activating potential of antimicrobial peptides contributes to antimicrobial efficacy and is predictive of the induction of bacterial resistance.Identification of human neutrophil-derived cathepsin G and azurocidin/CAP37 as chemoattractants for mononuclear cells and neutrophils.Stimulus-dependent impairment of the neutrophil oxidative burst response in lactoferrin-deficient mice.Differential killing of Actinobacillus actinomycetemcomitans and Capnocytophaga spp. by human neutrophil granule components.Human antimicrobial proteins effectors of innate immunity.Susceptibility to infectious diseases based on antimicrobial peptide production.Resistance to antimicrobial peptides in Gram-negative bacteria.Immune modulation by multifaceted cationic host defense (antimicrobial) peptides.Diverse functions of defensins and other antimicrobial peptides in periodontal tissues.Immunodeficiency as a component of recognizable syndromes.The giant organelles in beige and Chediak-Higashi fibroblasts are derived from late endosomes and mature lysosomes.Killing of staphylococci by θ-defensins involves membrane impairment and activation of autolytic enzymes The human cationic host defense peptide LL-37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system.Approach to the child with recurrent infections.H1 histones contribute to candidacidal activities of human epidermal extract.Vitamin D3 induces pro-LL-37 expression in myeloid precursors from patients with severe congenital neutropenia.

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P2860

Microbicidal/cytotoxic proteins of neutrophils are deficient in two disorders: Chediak-Higashi syndrome and "specific" granule deficiency.

http://www.wikidata.org/entity/Q34555280

description

1988 nî lūn-bûn

@nan

1988 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

1988 թվականի օգոստոսին հրատարակված գիտական հոդված

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1988年の論文

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1988年論文

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1988年論文

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1988年論文

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1988年論文

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1988年論文

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1988年论文

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name

Microbicidal/cytotoxic protein ...... "specific" granule deficiency.

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Microbicidal/cytotoxic protein ...... "specific" granule deficiency.

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Microbicidal/cytotoxic protein ...... "specific" granule deficiency.

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Microbicidal/cytotoxic protein ...... "specific" granule deficiency.

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Microbicidal/cytotoxic protein ...... "specific" granule deficiency.

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Microbicidal/cytotoxic protein ...... "specific" granule deficiency.

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Microbicidal/cytotoxic protein ...... "specific" granule deficiency.

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Microbicidal/cytotoxic protein ...... "specific" granule deficiency.

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Microbicidal/cytotoxic protein ...... "specific" granule deficiency.

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Journal of Clinical Investigation

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Microbicidal/cytotoxic protein ...... "specific" granule deficiency.

@en

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J A Metcalf

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J I Gallin

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L A Boxer

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R I Lehrer

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P2860

Defensins. Natural peptide antibiotics of human neutrophils

Measurement of protein using bicinchoninic acid

Neutrophil-mediated injury to endothelial cells. Enhancement by endotoxin and essential role of neutrophil elastase

Abnormal bactericidal, metabolic, and lysosomal functions of Chediak-Higashi Syndrome leukocytes

ELECTRON MICROSCOPE STUDIES ON THE DEGRANULATION OF RABBIT PERITONEAL LEUKOCYTES DURING PHAGOCYTOSIS.

Human neutrophil-specific granule deficiency: a model to assess the role of neutrophil-specific granules in the evolution of the inflammatory response.

Chédiak-Higashi syndrome neutrophils are characterized by the absence of both normal azurophilic granules.

Cytotoxicity for tumor cells of cationic proteins from human neutrophil granules

Specific protease deficiency in polymorphonuclear leukocytes of Chédiak-Higashi syndrome and beige mice.

Lysosomal elastase and cathepsin G in beige mice. Neutrophils of beige (Chediak-Higashi) mice selectively lack lysosomal elastase and cathepsin G.

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552-556

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10.1172/JCI113631

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2

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82

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20315602

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2841356

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303547

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