Microbicidal/cytotoxic proteins of neutrophils are deficient in two disorders: Chediak-Higashi syndrome and "specific" granule deficiency.
about
Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activityNeutrophil-specific granule deficiency results from a novel mutation with loss of function of the transcription factor CCAAT/enhancer binding protein epsilonCongenital defects in neutrophil dynamicsInteractions between neutrophil-derived antimicrobial peptides and airway epithelial cellsResistance to host antimicrobial peptides is necessary for Salmonella virulenceManual annotation and analysis of the defensin gene cluster in the C57BL/6J mouse reference genome.Comparative genomics and host resistance against infectious diseasesEnhancement of neonatal innate defense: effects of adding an N-terminal recombinant fragment of bactericidal/permeability-increasing protein on growth and tumor necrosis factor-inducing activity of gram-negative bacteria tested in neonatal cord blooAnimal antimicrobial peptides: an overview.Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases.In vitro killing of oral Capnocytophaga by granule fractions of human neutrophils is associated with cathepsin G activity.Antibiotic proteins of human neutrophils.Host defence peptides: antimicrobial and immunomodulatory activity and potential applications for tackling antibiotic-resistant infections.Antimicrobial peptides: properties and applicability.Selective defect in myeloid cell lactoferrin gene expression in neutrophil specific granule deficiencyMonocyte-chemotactic activity of defensins from human neutrophils.Skin fibroblasts from individuals with Chediak-Higashi Syndrome (CHS) exhibit hyposensitive immunogenic response.In vitro studies on the antimicrobial peptide human beta-defensin 9 (HBD9): signalling pathways and pathogen-related response (an American Ophthalmological Society thesis).In vitro sensitivity of oral, gram-negative, facultative bacteria to the bactericidal activity of human neutrophil defensins.Human α-defensin expression is not dependent on CCAAT/enhancer binding protein-ε in a murine model.Infections in patients with inherited defects in phagocytic function.The role of defensins in lung biology and therapy.The antimicrobial propeptide hCAP-18 plasma levels in neutropenia of various aetiologies: a prospective study.Psoriatic scales: a promising source for the isolation of human skin-derived antimicrobial proteins.The PhoQ-activating potential of antimicrobial peptides contributes to antimicrobial efficacy and is predictive of the induction of bacterial resistance.Identification of human neutrophil-derived cathepsin G and azurocidin/CAP37 as chemoattractants for mononuclear cells and neutrophils.Stimulus-dependent impairment of the neutrophil oxidative burst response in lactoferrin-deficient mice.Differential killing of Actinobacillus actinomycetemcomitans and Capnocytophaga spp. by human neutrophil granule components.Human antimicrobial proteins effectors of innate immunity.Susceptibility to infectious diseases based on antimicrobial peptide production.Resistance to antimicrobial peptides in Gram-negative bacteria.Immune modulation by multifaceted cationic host defense (antimicrobial) peptides.Diverse functions of defensins and other antimicrobial peptides in periodontal tissues.Immunodeficiency as a component of recognizable syndromes.The giant organelles in beige and Chediak-Higashi fibroblasts are derived from late endosomes and mature lysosomes.Killing of staphylococci by θ-defensins involves membrane impairment and activation of autolytic enzymesThe human cationic host defense peptide LL-37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system.Approach to the child with recurrent infections.H1 histones contribute to candidacidal activities of human epidermal extract.Vitamin D3 induces pro-LL-37 expression in myeloid precursors from patients with severe congenital neutropenia.
P2860
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P2860
Microbicidal/cytotoxic proteins of neutrophils are deficient in two disorders: Chediak-Higashi syndrome and "specific" granule deficiency.
description
1988 nî lūn-bûn
@nan
1988 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Microbicidal/cytotoxic protein ...... "specific" granule deficiency.
@ast
Microbicidal/cytotoxic protein ...... "specific" granule deficiency.
@en
Microbicidal/cytotoxic protein ...... "specific" granule deficiency.
@nl
type
label
Microbicidal/cytotoxic protein ...... "specific" granule deficiency.
@ast
Microbicidal/cytotoxic protein ...... "specific" granule deficiency.
@en
Microbicidal/cytotoxic protein ...... "specific" granule deficiency.
@nl
prefLabel
Microbicidal/cytotoxic protein ...... "specific" granule deficiency.
@ast
Microbicidal/cytotoxic protein ...... "specific" granule deficiency.
@en
Microbicidal/cytotoxic protein ...... "specific" granule deficiency.
@nl
P2093
P2860
P356
P1476
Microbicidal/cytotoxic protein ...... "specific" granule deficiency.
@en
P2093
J A Metcalf
J I Gallin
R I Lehrer
P2860
P304
P356
10.1172/JCI113631
P407
P50
P577
1988-08-01T00:00:00Z