Up-regulation of endothelial delta-like 4 expression correlates with vessel maturation in bladder cancer.
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Tumor angiogenesis: pericytes and maturation are not to be ignoredTips, stalks, tubes: notch-mediated cell fate determination and mechanisms of tubulogenesis during angiogenesisAntibody drug-conjugates targeting the tumor vasculature: Current and future developmentsDll1- and dll4-mediated notch signaling are required for homeostasis of intestinal stem cellsA novel method of differential gene expression analysis using multiple cDNA libraries applied to the identification of tumour endothelial genes.Spatially addressed combinatorial protein libraries for recombinant antibody discovery and optimization.Expression of vascular notch ligand delta-like 4 and inflammatory markers in breast cancerDelta-like ligand 4 (Dll4) predicts the prognosis of clear cell renal cell carcinoma, and anti-Dll4 suppresses tumor growth in vivo.The antiangiogenic 16K prolactin impairs functional tumor neovascularization by inhibiting vessel maturation.Delta-like ligand 4: A predictor of poor prognosis in clear cell renal cell carcinomaDelta-like ligand 4-Notch signaling regulates bone marrow-derived pericyte/vascular smooth muscle cell formationBiological roles of the Delta family Notch ligand Dll4 in tumor and endothelial cells in ovarian cancer.Interleukin-6 Stimulates Defective Angiogenesis.Endothelial Dll4 overexpression reduces vascular response and inhibits tumor growth and metastasization in vivoInfluence of vascular endothelial growth factor single nucleotide polymorphisms on non-small cell lung cancer tumor angiogenesis.A notch1 ectodomain construct inhibits endothelial notch signaling, tumor growth, and angiogenesis.Moving beyond VEGF for anti-angiogenesis strategies in gynecologic cancerA phase I study of the combination of ro4929097 and cediranib in patients with advanced solid tumours (PJC-004/NCI 8503).Clinical implications of DLL4 expression in gastric cancerIntrinsic selectivity of Notch 1 for Delta-like 4 over Delta-like 1.Implications of Dll4-Notch signaling activation in primary glioblastoma multiforme.Notch signaling regulates tumor angiogenesis by diverse mechanisms.VEGF and Delta-Notch: interacting signalling pathways in tumour angiogenesis.Expression of delta-like ligand 4 (Dll4) and markers of hypoxia in colon cancer.The Notch ligand Delta-like 4 (DLL4) as a target in angiogenesis-based cancer therapy?Role of Notch signaling in colorectal cancer.Notch regulation of tumor angiogenesis.Notch signalling in solid tumours: a little bit of everything but not all the time.Dll4-Notch signaling as a therapeutic target in tumor angiogenesis.Novel targets for VEGF-independent anti-angiogenic drugs.Current status and future prospects for anti-angiogenic therapies in cancer.Notch functions in developmental and tumour angiogenesis by diverse mechanisms.JAGGED1 signaling regulates hemangioma stem cell-to-pericyte/vascular smooth muscle cell differentiation.Vesicular trafficking mechanisms in endothelial cells as modulators of the tumor vasculature and targets of antiangiogenic therapies.Notch1 stimulation induces a vascularization switch with pericyte-like cell differentiation of glioblastoma stem cells.IFNγ-responsiveness of endothelial cells leads to efficient angiostasis in tumours involving down-regulation of Dll4.Inhibition of ADAM-17 more effectively down-regulates the Notch pathway than that of γ-secretase in renal carcinoma.Targeting DLL4 in tumors shows preclinical activity but potentially significant toxicity.DLL4 as a predictor of pelvic lymph node metastasis and a novel prognostic biomarker in patients with early-stage cervical cancer.MicroRNA-30a as a prognostic factor in urothelial carcinoma of bladder inhibits cellular malignancy by antagonising Notch1.
P2860
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P2860
Up-regulation of endothelial delta-like 4 expression correlates with vessel maturation in bladder cancer.
description
2006 nî lūn-bûn
@nan
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Up-regulation of endothelial d ...... maturation in bladder cancer.
@ast
Up-regulation of endothelial d ...... maturation in bladder cancer.
@en
Up-regulation of endothelial d ...... maturation in bladder cancer.
@nl
type
label
Up-regulation of endothelial d ...... maturation in bladder cancer.
@ast
Up-regulation of endothelial d ...... maturation in bladder cancer.
@en
Up-regulation of endothelial d ...... maturation in bladder cancer.
@nl
prefLabel
Up-regulation of endothelial d ...... maturation in bladder cancer.
@ast
Up-regulation of endothelial d ...... maturation in bladder cancer.
@en
Up-regulation of endothelial d ...... maturation in bladder cancer.
@nl
P2093
P1476
Up-regulation of endothelial d ...... maturation in bladder cancer.
@en
P2093
David W Cranston
Graham Steers
Ji-Liang Li
Karena Le Monnier
Mark Rochester
Michael S Dobbie
Nilay S Patel
Richard Poulsom
P304
P356
10.1158/1078-0432.CCR-06-0285
P407
P577
2006-08-01T00:00:00Z