High glucose induced alteration of SIRTs in endothelial cells causes rapid aging in a p300 and FOXO regulated pathway.
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The endothelium abridges insulin resistance to premature agingRole of Sirtuins in Linking Metabolic Syndrome with DepressionCellular senescence in aging and age-related disease: from mechanisms to therapyRedox regulation of FoxO transcription factorsSIRTain regulators of premature senescence and accelerated agingCellular and molecular biology of aging endothelial cellsRedox regulation of endothelial cell fateIncreased Oxidative and Nitrative Stress Accelerates Aging of the Retinal Vasculature in the Diabetic RetinaHyperglycemia causes cellular senescence via a SGLT2- and p21-dependent pathway in proximal tubules in the early stage of diabetic nephropathy.Functional genetic variants within the SIRT2 gene promoter in acute myocardial infarction.PLK2 Plays an Essential Role in High D-Glucose-Induced Apoptosis, ROS Generation and Inflammation in Podocytes.The Role of SIRT1 in Diabetic Kidney Disease.Stiffness memory of EA.hy926 endothelial cells in response to chronic hyperglycemiaHigh glucose induced oxidative stress and apoptosis in cardiac microvascular endothelial cells are regulated by FoxO3a.Effects of nutritional components on agingSirt1 deletion leads to enhanced inflammation and aggravates endotoxin-induced acute kidney injurySIRT1 is a regulator in high glucose-induced inflammatory response in RAW264.7 cells.Sirtuins, aging, and cardiovascular risks.Metformin and Resveratrol Inhibited High Glucose-Induced Metabolic Memory of Endothelial Senescence through SIRT1/p300/p53/p21 PathwayThe Histone Deacetylase Sirtuin 1 Is Reduced in Systemic Sclerosis and Abrogates Fibrotic Responses by Targeting Transforming Growth Factor β Signaling.Targeting FoxO1 with AS1842856 suppresses adipogenesis.SIRT3 Mediates the Antioxidant Effect of Hydrogen Sulfide in Endothelial Cells.Mild endothelial dysfunction in Sirt3 knockout mice fed a high-cholesterol diet: protective role of a novel C/EBP-β-dependent feedback regulation of SOD2SIRT6 protects against endothelial dysfunction and atherosclerosis in miceA steroid like phytochemical Antcin M is an anti-aging reagent that eliminates hyperglycemia-accelerated premature senescence in dermal fibroblasts by direct activation of Nrf2 and SIRT-1.Molecular biology of atherosclerosis.Common neurodegenerative pathways in obesity, diabetes, and Alzheimer's disease.Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts.Retinal Diseases Associated with Oxidative Stress and the Effects of a Free Radical Scavenger (Edaravone).The role of dietary carbohydrates in organismal aging.AGEs Decreased SIRT3 Expression and SIRT3 Activation Protected AGEs-Induced EPCs' Dysfunction and Strengthened Anti-oxidant Capacity.Stachydrine ameliorates high-glucose induced endothelial cell senescence and SIRT1 downregulation.Emerging Roles for MicroRNAs in Diabetic Microvascular Disease: Novel Targets for Therapy.Sirt1 Inhibits Oxidative Stress in Vascular Endothelial Cells.5-methoxytryptophan protects MSCs from stress induced premature senescence by upregulating FoxO3a and mTOR.Short-term High Dose of Quercetin and Resveratrol Alters Aging Markers in Human Kidney Cells.Evaluation of Energy Balance on Human Telomerase Reverse Transcriptase (hTERT) Alternative Splicing by Semi-quantitative RT-PCR in Human Umbilical Vein Endothelial Cells.Biochemical characterization of sirtuin 6 in the brain and its involvement in oxidative stress response.Oxidative stress induces endothelial cell senescence via downregulation of Sirt6.SIRT1 reduction causes renal and retinal injury in diabetes through endothelin 1 and transforming growth factor β1.
P2860
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P2860
High glucose induced alteration of SIRTs in endothelial cells causes rapid aging in a p300 and FOXO regulated pathway.
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
High glucose induced alteratio ...... 00 and FOXO regulated pathway.
@ast
High glucose induced alteratio ...... 00 and FOXO regulated pathway.
@en
High glucose induced alteratio ...... 00 and FOXO regulated pathway.
@nl
type
label
High glucose induced alteratio ...... 00 and FOXO regulated pathway.
@ast
High glucose induced alteratio ...... 00 and FOXO regulated pathway.
@en
High glucose induced alteratio ...... 00 and FOXO regulated pathway.
@nl
prefLabel
High glucose induced alteratio ...... 00 and FOXO regulated pathway.
@ast
High glucose induced alteratio ...... 00 and FOXO regulated pathway.
@en
High glucose induced alteratio ...... 00 and FOXO regulated pathway.
@nl
P2093
P2860
P1433
P1476
High glucose induced alteratio ...... 00 and FOXO regulated pathway.
@en
P2093
Rokhsana Mortuza
Shali Chen
Subhrojit Sen
P2860
P304
P356
10.1371/JOURNAL.PONE.0054514
P407
P577
2013-01-16T00:00:00Z