Epigenetic inactivation of inhibitor of differentiation 4 (Id4) correlates with prostate cancer
about
Id4 deficiency attenuates prostate development and promotes PIN-like lesions by regulating androgen receptor activity and expression of NKX3.1 and PTENInhibitor of differentiation 4 (ID4) inactivation promotes de novo steroidogenesis and castration-resistant prostate cancer.Evaluation of candidate spermatogonial markers ID4 and GPR125 in testes of adult human cadaveric organ donors.Distinct phenotypes of human prostate cancer cells associate with different adaptation to hypoxia and pro-inflammatory gene expression.Id4 promotes cell proliferation in hepatocellular carcinoma.Prostate cancer epigenome.Inhibitor of differentiation 4 (ID4): From development to cancerInactivation of ID4 promotes a CRPC phenotype with constitutive AR activation through FKBP52.Inhibitor of differentiation 4 (ID4) acts as an inhibitor of ID-1, -2 and -3 and promotes basic helix loop helix (bHLH) E47 DNA binding and transcriptional activity.Interferon inducible antiviral MxA is inversely associated with prostate cancer and regulates cell cycle, invasion and Docetaxel induced apoptosis.EZH2 dependent H3K27me3 is involved in epigenetic silencing of ID4 in prostate cancer.Id4 suppresses MMP2-mediated invasion of glioblastoma-derived cells by direct inactivation of Twist1 function.Id4 dependent acetylation restores mutant-p53 transcriptional activity.Id4 promotes senescence and sensitivity to doxorubicin-induced apoptosis in DU145 prostate cancer cells.Intra-tumoral delivery of functional ID4 protein via PCL/maltodextrin nano-particle inhibits prostate cancer growthID4 promotes AR expression and blocks tumorigenicity of PC3 prostate cancer cells.
P2860
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P2860
Epigenetic inactivation of inhibitor of differentiation 4 (Id4) correlates with prostate cancer
description
2012 nî lūn-bûn
@nan
2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Epigenetic inactivation of inh ...... orrelates with prostate cancer
@ast
Epigenetic inactivation of inh ...... orrelates with prostate cancer
@en
Epigenetic inactivation of inhibitor of differentiation 4
@nl
type
label
Epigenetic inactivation of inh ...... orrelates with prostate cancer
@ast
Epigenetic inactivation of inh ...... orrelates with prostate cancer
@en
Epigenetic inactivation of inhibitor of differentiation 4
@nl
prefLabel
Epigenetic inactivation of inh ...... orrelates with prostate cancer
@ast
Epigenetic inactivation of inh ...... orrelates with prostate cancer
@en
Epigenetic inactivation of inhibitor of differentiation 4
@nl
P2093
P2860
P356
P1433
P1476
Epigenetic inactivation of inh ...... orrelates with prostate cancer
@en
P2093
Divya Patel
Jaideep Chaudhary
Jason Carey
Pankaj Sharma
Swathi Chinaranagari
P2860
P304
P356
10.1002/CAM4.16
P407
P577
2012-08-02T00:00:00Z