TGF-beta requires CTLA-4 early after T cell activation to induce FoxP3 and generate adaptive CD4+CD25+ regulatory cells.
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Acquisition of suppressive function by activated human CD4+ CD25- T cells is associated with the expression of CTLA-4 not FoxP3T cell receptor signalling in the control of regulatory T cell differentiation and functionInduced regulatory T cells: mechanisms of conversion and suppressive potentialMechanisms underlying the induction of regulatory T cells and its relevance in the adaptive immune response in parasitic infectionsCellular and molecular determinants for the development of natural and induced regulatory T cellsCTLA-4 trafficking and surface expressionThe Polyunsaturated Fatty Acids Arachidonic Acid and Docosahexaenoic Acid Induce Mouse Dendritic Cells Maturation but Reduce T-Cell Responses In VitroPD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumorsRegulatory T cells: mechanisms of differentiation and functionInduction of auto-reactive regulatory T cells by stimulation with immature autologous dendritic cells.GATA3-driven Th2 responses inhibit TGF-beta1-induced FOXP3 expression and the formation of regulatory T cells.CD8+ CD205+ splenic dendritic cells are specialized to induce Foxp3+ regulatory T cells.Therapeutic potential of TGF-β-induced CD4(+) Foxp3(+) regulatory T cells in autoimmune diseases.Induced T regulatory cells suppress osteoclastogenesis and bone erosion in collagen-induced arthritis better than natural T regulatory cells.Antigen-Pulsed CpG-ODN-Activated Dendritic Cells Induce Host-Protective Immune Response by Regulating the T Regulatory Cell Functioning in Leishmania donovani-Infected Mice: Critical Role of CXCL10.Regulatory T Cells in Allergy and Asthma.Synergistic effect of TGF-beta superfamily members on the induction of Foxp3+ TregVasoactive intestinal peptide induces cell cycle arrest and regulatory functions in human T cells at multiple levels.A novel pancreatic β-cell targeting bispecific-antibody (BsAb) can prevent the development of type 1 diabetes in NOD miceDendritic cell-directed CTLA-4 engagement during pancreatic beta cell antigen presentation delays type 1 diabetes.Secretory IgA in complex with Lactobacillus rhamnosus potentiates mucosal dendritic cell-mediated Treg cell differentiation via TLR regulatory proteins, RALDH2 and secretion of IL-10 and TGF-β.Pathogenesis of allergic airway inflammation.Control of Th2-mediated inflammation by regulatory T cells.TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo.An increase of CD83+ dendritic cells ex vivo correlates with increased regulatory T cells in patients with active eosinophilic granulomatosis and polyangiitis.An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells.Tumour cell generation of inducible regulatory T-cells in multiple myeloma is contact-dependent and antigen-presenting cell-independent.Role of CD4CD25FOXP3 Regulatory T Cells in Psoriasis.The role of the transcription factor Foxp3 in the development of regulatory T cells.The regulation of Foxp3 expression in regulatory CD4(+)CD25(+)T cells: multiple pathways on the road.Dysregulated expression of both the costimulatory CD28 and inhibitory CTLA-4 molecules in PB T cells of advanced cervical cancer patients suggests systemic immunosuppression related to disease progressionControl of regulatory T cell lineage commitment and maintenance.Blockade of LFA-1 augments in vitro differentiation of antigen-induced Foxp3⁺ Treg cells.Elevated levels of CD4(+)CD25(+)FoxP3(+) T cells in systemic sclerosis patients contribute to the secretion of IL-17 and immunosuppression dysfunction.Differential CTLA-4 expression in human CD4+ versus CD8+ T cells is associated with increased NFAT1 and inhibition of CD4+ proliferation.Costimulation couture: a designer approach to regulating autoimmunity.CTLA-4 (CD152) controls homeostasis and suppressive capacity of regulatory T cells in mice.Immunoregulatory pathways controlling progression of autoimmunity in NOD mice.Ctla-4 modulates the differentiation of inducible Foxp3+ Treg cells but IL-10 mediates their function in experimental autoimmune encephalomyelitis.T regulatory cells: aid or hindrance in the clearance of disease?
P2860
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P2860
TGF-beta requires CTLA-4 early after T cell activation to induce FoxP3 and generate adaptive CD4+CD25+ regulatory cells.
description
2006 nî lūn-bûn
@nan
2006 թուականի Մարտին հրատարակուած գիտական յօդուած
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2006 թվականի մարտին հրատարակված գիտական հոդված
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2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
name
TGF-beta requires CTLA-4 early ...... ve CD4+CD25+ regulatory cells.
@ast
TGF-beta requires CTLA-4 early ...... ve CD4+CD25+ regulatory cells.
@en
TGF-beta requires CTLA-4 early ...... ve CD4+CD25+ regulatory cells.
@nl
type
label
TGF-beta requires CTLA-4 early ...... ve CD4+CD25+ regulatory cells.
@ast
TGF-beta requires CTLA-4 early ...... ve CD4+CD25+ regulatory cells.
@en
TGF-beta requires CTLA-4 early ...... ve CD4+CD25+ regulatory cells.
@nl
prefLabel
TGF-beta requires CTLA-4 early ...... ve CD4+CD25+ regulatory cells.
@ast
TGF-beta requires CTLA-4 early ...... ve CD4+CD25+ regulatory cells.
@en
TGF-beta requires CTLA-4 early ...... ve CD4+CD25+ regulatory cells.
@nl
P2093
P1476
TGF-beta requires CTLA-4 early ...... ve CD4+CD25+ regulatory cells.
@en
P2093
David A Horwitz
J Dixon Gray
Ju Hua Wang
Kyoung Soo Kim
Song Guo Zheng
William Stohl
P304
P356
10.4049/JIMMUNOL.176.6.3321
P407
P577
2006-03-01T00:00:00Z