Thymoquinone up-regulates PTEN expression and induces apoptosis in doxorubicin-resistant human breast cancer cells
about
Thymoquinone: an emerging natural drug with a wide range of medical applicationsChloroform Extract of Rasagenthi Mezhugu, a Siddha Formulation, as an Evidence-Based Complementary and Alternative Medicine for HPV-Positive Cervical CancersThymoquinone inhibits autophagy and induces cathepsin-mediated, caspase-independent cell death in glioblastoma cellsNotch signaling is important for epithelial-mesenchymal transition induced by low concentrations of doxorubicin in osteosarcoma cell lines.Therapeutic Implications of Black Seed and Its Constituent Thymoquinone in the Prevention of Cancer through Inactivation and Activation of Molecular Pathways.Essential oils and their constituents as anticancer agents: a mechanistic view.Antibacterial activity of Thymoquinone, an active principle of Nigella sativa and its potency to prevent bacterial biofilm formation.Anticancer property of Bryophyllum pinnata (Lam.) Oken. leaf on human cervical cancer cellsCurcumin enhances the efficacy of chemotherapy by tailoring p65NFκB-p300 cross-talk in favor of p53-p300 in breast cancer.Chemoresistance to doxorubicin induces epithelial-mesenchymal transition via upregulation of transforming growth factor β signaling in HCT116 colon cancer cells.PI3K/Akt inhibition and down-regulation of BCRP re-sensitize MCF7 breast cancer cell line to mitoxantrone chemotherapy.Antagonism between curcumin and the topoisomerase II inhibitor etoposide: a study of DNA damage, cell cycle regulation and death pathways.Effect of total hydroalcholic extract of Nigella sativa and its n-hexane and ethyl acetate fractions on ACHN and GP-293 cell lines.Thymoquinone in the clinical treatment of cancer: Fact or fiction?Thymoquinone regulates gene expression levels in the estrogen metabolic and interferon pathways in MCF7 breast cancer cells.Plant volatiles: production, function and pharmacology.Immunity: plants as effective mediators.c-Fos is involved in inhibition of human bladder carcinoma T24 cells by brazilin.Thymoquinone Modulates Blood Coagulation in Vitro via Its Effects on Inflammatory and Coagulation Pathways.Insights into the molecular interactions of thymoquinone with histone deacetylase: evaluation of the therapeutic intervention potential against breast cancer.The combination of thymoquinone and paclitaxel shows anti-tumor activity through the interplay with apoptosis network in triple-negative breast cancer.DNA damage and inhibition of akt pathway in mcf-7 cells and ehrlich tumor in mice treated with 1,4-naphthoquinones in combination with ascorbate.Thymoquinone Pretreatment Overcomes the Insensitivity and Potentiates the Antitumor Effect of Gemcitabine Through Abrogation of Notch1, PI3K/Akt/mTOR Regulated Signaling Pathways in Pancreatic Cancer.Thymoquinone inhibits proliferation and invasion of human nonsmall-cell lung cancer cells via ERK pathway.Thymoquinone, a bioactive component of black caraway seeds, causes G1 phase cell cycle arrest and apoptosis in triple-negative breast cancer cells with mutant p53.Genistein induces G2/M arrest in gastric cancer cells by increasing the tumor suppressor PTEN expression.Thymoquinone induces mitochondria-mediated apoptosis in acute lymphoblastic leukaemia in vitro.Pronounced transcriptional regulation of apoptotic and TNF-NF-kappa-B signaling genes during the course of thymoquinone mediated apoptosis in HeLa cells.Anti-cancer properties and mechanisms of action of thymoquinone, the major active ingredient of Nigella sativa.Oridonin induces apoptosis, inhibits migration and invasion on highly-metastatic human breast cancer cells.Thymoquinone, as an anticancer molecule: from basic research to clinical investigation.Thymoquinone as an anticancer agent: evidence from inhibition of cancer cells viability and invasion in vitro and tumor growth in vivo.Arsenic trioxide induces G2/M arrest in hepatocellular carcinoma cells by increasing the tumor suppressor PTEN expression.Thymoquinone as a Potential Adjuvant Therapy for Cancer Treatment: Evidence from Preclinical Studies.Ars2 is overexpressed in human cholangiocarcinomas and its depletion increases PTEN and PDCD4 by decreasing microRNA-21.North African Medicinal Plants Traditionally Used in Cancer Therapy.Dietary Natural Products for Prevention and Treatment of Breast Cancer.Therapeutic Potential and Pharmaceutical Development of Thymoquinone: A Multitargeted Molecule of Natural Origin.Enhancing conventional chemotherapy drug cisplatin-induced anti-tumor effects on human gastric cancer cells both in vitro and in vivo by Thymoquinone targeting PTEN gene.Regulation of the tumor suppressor PTEN by natural anticancer compounds.
P2860
Q28085618-32F39817-9ABD-4051-B1AC-17F005C82A49Q28393213-8A5DDD5F-C849-46F1-B615-21FFBAD3D731Q28536969-EE4BCEF1-390B-4D6B-852F-A6EA80A51098Q33598608-D4A21106-BDB4-42CE-9C2B-7D0518D336ABQ33736242-A8365E26-1F4D-4DCC-8861-4F7032B54C75Q33805315-0B9D88B5-65ED-4703-8375-9E687F8F5962Q33871653-F2F4894A-BCAC-48FE-8A07-E5622726152EQ34190322-ACCC9822-0A54-40A6-9212-3E556CB4C2D7Q35604870-7C106F03-5B0E-4E89-9ABF-76133364B81CQ35628337-D5CDC961-4D0A-4BA1-8399-A311A5AFA106Q35763457-CB439F9D-411C-4263-9D20-A22B6EC3114AQ36289907-BA07A73A-0122-487F-99E9-A8DEE19D567FQ36534963-475A2152-515C-4A1D-95FD-3F8078D5B5DEQ37346510-2A258C24-56C7-4B54-BB7A-92BDF96A377AQ37404536-F7E4AFF4-0CF9-481F-B869-4E5619E2D34FQ37889127-E7C7F94F-6C2C-42A8-9069-8C15139F5D3FQ38190597-A75ED25C-7EF9-4FA9-ABCF-7EF6D8D4E851Q38464686-FCB8F4D6-637D-4219-98A5-C8E936A7842EQ38780835-632EE0B5-A368-4567-BE9D-57EC9C7BFE83Q38821833-F05C92FC-ED4B-4820-9E09-E7287AE0C80CQ38824990-CE27BB8E-98C7-4A08-91F6-C538F2C56E63Q38897164-F35A39CF-EFCE-4357-862D-4B32604706E2Q38945152-E636D392-02F0-4BE6-8503-89A46F31F672Q38954969-033E161F-6216-4D3F-821C-5681ABC483B1Q39020051-467D3CCC-0C54-4B44-BB88-BAAB56FBD0A9Q39093740-AE5AAC63-1935-4E78-ABE8-0C325301BF13Q39095981-E4EBEC82-0CCC-4736-B385-D64F4DB28B41Q39110492-BBD59210-44BC-4B6A-B6A6-83E27E7A4838Q39111541-721A0549-5815-4715-A528-3D1E818DF4BFQ39207391-C5F803E1-9E98-4BD1-BF61-E40FB4337D95Q39295835-95FD7B93-6C53-45C8-9419-8F979486C86BQ39315887-614DE508-F064-47B0-98BD-AA33948C8524Q39325807-3788655B-4C51-4AC6-8CA1-125E820B03E2Q39403430-A2215DBB-C418-4CB2-BD4F-25D3AB735200Q39418655-48914748-D588-4792-BB0A-3373E0AA365DQ39427056-34172C6E-C618-4024-AB76-638F720F8448Q39429454-F73ECE7C-002F-4688-9D48-0BE0BCC6C6CBQ42363810-03E23F43-D488-412F-B030-0F3713F094C1Q44295635-88CCE488-8B3B-431F-8181-13BE43DF754CQ47691876-9CC34265-B66B-440B-B5A0-CD0EE0D0BD42
P2860
Thymoquinone up-regulates PTEN expression and induces apoptosis in doxorubicin-resistant human breast cancer cells
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Thymoquinone up-regulates PTEN ...... tant human breast cancer cells
@ast
Thymoquinone up-regulates PTEN ...... tant human breast cancer cells
@en
Thymoquinone up-regulates PTEN ...... tant human breast cancer cells
@nl
type
label
Thymoquinone up-regulates PTEN ...... tant human breast cancer cells
@ast
Thymoquinone up-regulates PTEN ...... tant human breast cancer cells
@en
Thymoquinone up-regulates PTEN ...... tant human breast cancer cells
@nl
prefLabel
Thymoquinone up-regulates PTEN ...... tant human breast cancer cells
@ast
Thymoquinone up-regulates PTEN ...... tant human breast cancer cells
@en
Thymoquinone up-regulates PTEN ...... tant human breast cancer cells
@nl
P2093
P2860
P1433
P1476
Thymoquinone up-regulates PTEN ...... tant human breast cancer cells
@en
P2093
Altaf A Wani
Bassant M Barakat
Gulzar Wani
Ira Racoma
Mohamed A El-Mahdy
Qianzheng Zhu
Zubair I Shah
P2860
P356
10.1016/J.MRFMMM.2010.10.007
P407
P577
2010-10-30T00:00:00Z